Leanne M. Redman
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View article: Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain: a systematic review and meta-analysis
Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain: a systematic review and meta-analysis Open
View article: Association between physical activity energy expenditure and markers of healthspan during prolonged calorie restriction in individuals without obesity: observations from the CALERIE™ phase 2 randomized controlled trial
Association between physical activity energy expenditure and markers of healthspan during prolonged calorie restriction in individuals without obesity: observations from the CALERIE™ phase 2 randomized controlled trial Open
Background It is unclear how physical activity energy expenditure (PAEE) influences calorie restriction (CR)-induced benefits in individuals without obesity. We examined associations between PAEE and healthspan markers and physical activit…
View article: LIFE-Moms: effects of multicomponent lifestyle randomized control trial on physical activity during pregnancy in women with overweight and obesity
LIFE-Moms: effects of multicomponent lifestyle randomized control trial on physical activity during pregnancy in women with overweight and obesity Open
Background This report details the effect of LIFE-Mom’s multicomponent lifestyle interventions on physical activity (PA) and inactivity time across pregnancy (2nd and 3rd trimesters) and their effect on gestational weight gain (GWG) and ma…
View article: Examining the Impact of a Codeveloped Multicomponent Mobile eHealth Lifestyle Intervention on Physical Activity and Its Association With Gestational Weight Gain in Underserved Women: A Statewide Randomized Controlled Trial
Examining the Impact of a Codeveloped Multicomponent Mobile eHealth Lifestyle Intervention on Physical Activity and Its Association With Gestational Weight Gain in Underserved Women: A Statewide Randomized Controlled Trial Open
Background Underserved pregnant women have a greater risk of excessive or inadequate gestational weight gain (GWG) and adverse perinatal outcomes. In the United States, the Special Supplemental Nutrition Program for Women, Infants, and Chi…
View article: Metabolic Health and Heterogenous Outcomes of Prenatal Interventions
Metabolic Health and Heterogenous Outcomes of Prenatal Interventions Open
Importance Prenatal intensive behavioral therapy (IBT) interventions that promote adequate gestational weight gain (GWG) have had variable and mostly modest effects on clinically relevant maternal and infant outcomes. It is unknown whether…
View article: Effect of caloric restriction on organ size and its contribution to metabolic adaptation: an ancillary analysis of CALERIE 2
Effect of caloric restriction on organ size and its contribution to metabolic adaptation: an ancillary analysis of CALERIE 2 Open
Caloric restriction (CR) can enhance human health, though underlying mechanisms, particularly related to energy expenditure, remain unclear. This ancillary investigation of the only randomized controlled trial of long-term CR in normal-wei…
View article: Energy expenditure and obesity across the economic spectrum
Energy expenditure and obesity across the economic spectrum Open
Global economic development has been associated with an increased prevalence of obesity and related health problems. Increased caloric intake and reduced energy expenditure are both cited as development-related contributors to the obesity …
View article: Exploring Individual Factors Affecting Endothelial Function Response Variability in Aging: Implications for Precision Nutrition
Exploring Individual Factors Affecting Endothelial Function Response Variability in Aging: Implications for Precision Nutrition Open
Aging is a major non-modifiable risk factor for cardiovascular disease (CVD), in part due to its detrimental effects on vascular endothelial function. Dietary interventions, including those rich in plant-based components or following dieta…
View article: The Effects of a Co-developed Perinatal e-health Intervention for Underserved Women on Maternal Diet: A Secondary Analysis of the “SmartMoms in WIC” Randomized Clinical Trial
The Effects of a Co-developed Perinatal e-health Intervention for Underserved Women on Maternal Diet: A Secondary Analysis of the “SmartMoms in WIC” Randomized Clinical Trial Open
View article: Strategies and Challenges for Recruitment of Young Healthy Participants in the Dietary Approaches for Longevity and Health (DiAL Health) Pilot Trial
Strategies and Challenges for Recruitment of Young Healthy Participants in the Dietary Approaches for Longevity and Health (DiAL Health) Pilot Trial Open
View article: The Impact of Diet Quality During Long-Term Caloric Restriction on Blood Pressure: An Analysis of CALERIE™ 2
The Impact of Diet Quality During Long-Term Caloric Restriction on Blood Pressure: An Analysis of CALERIE™ 2 Open
View article: Effect of Caloric Restriction on Organ Size and Its Contribution to Metabolic Adaptation: An Ancillary Analysis of CALERIE 2
Effect of Caloric Restriction on Organ Size and Its Contribution to Metabolic Adaptation: An Ancillary Analysis of CALERIE 2 Open
View article: The Effect of Leptin Phenotypes on Weight Change and Energy Expenditure Responses to Acute and Prolonged Positive or Negative Energy Balance
The Effect of Leptin Phenotypes on Weight Change and Energy Expenditure Responses to Acute and Prolonged Positive or Negative Energy Balance Open
View article: A Survey Examining the Association Between Perceived Pain and Mediterranean Diet Eating Pattern in Individuals With Endometriosis
A Survey Examining the Association Between Perceived Pain and Mediterranean Diet Eating Pattern in Individuals With Endometriosis Open
View article: Author Correction: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake
Author Correction: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake Open
View article: Trends in adverse pregnancy outcomes in Louisiana, 2017 to 2022
Trends in adverse pregnancy outcomes in Louisiana, 2017 to 2022 Open
View article: The effect of a leptin phenotype on weight change and energy expenditure responses to acute and prolonged energetic stressors
The effect of a leptin phenotype on weight change and energy expenditure responses to acute and prolonged energetic stressors Open
Leptin is linked to body fat, but unexplained variation remains. This study challenges the idea that distinct leptin phenotypes—characterized by relatively high or low leptin concentration for a given level of body fat—affects energy expen…
View article: Examining the Impact of a Codeveloped Multicomponent Mobile eHealth Lifestyle Intervention on Physical Activity and Its Association With Gestational Weight Gain in Underserved Women: A Statewide Randomized Controlled Trial (Preprint)
Examining the Impact of a Codeveloped Multicomponent Mobile eHealth Lifestyle Intervention on Physical Activity and Its Association With Gestational Weight Gain in Underserved Women: A Statewide Randomized Controlled Trial (Preprint) Open
BACKGROUND Underserved pregnant women have a greater risk of excessive or inadequate gestational weight gain (GWG) and adverse perinatal outcomes. In the United States, the Special Supplemental Nutrition Program for Women, Infants, and Ch…
View article: Estimating energy requirements from Dietary Reference Intakes for pregnant people with obesity using wearables
Estimating energy requirements from Dietary Reference Intakes for pregnant people with obesity using wearables Open
Objective Estimating physical activity levels (PAL) is difficult outside of the laboratory, and patient‐reported PAL are often overestimated. Herein, we determine the importance of selecting the correct PAL when computing estimated energy …
View article: Validation of a novel approach to assess metabolic flexibility to a high‐fat meal in a whole‐body room calorimeter
Validation of a novel approach to assess metabolic flexibility to a high‐fat meal in a whole‐body room calorimeter Open
Objective Metabolic inflexibility to Western high‐fat diets may contribute to the obesity epidemic. However, validated methods for assessing metabolic flexibility (MetFlex) to high‐fat meals are currently lacking. The purpose of this study…
View article: Protocol for a randomised controlled trial of a weight maintenance intervention to promote fat loss in pregnant individuals with obesity
Protocol for a randomised controlled trial of a weight maintenance intervention to promote fat loss in pregnant individuals with obesity Open
Introduction In pregnancy, people with obesity or excess adiposity are prone to excess gestational weight gain (GWG) and have the highest risks for multiple maternal morbidities. Epidemiological studies suggest that the lowest incidence of…
View article: Effects of Infant Formula Supplemented With Prebiotics on the Gut Microbiome, Gut Environment, Growth Parameters, and Safety and Tolerance: A Systematic Review and Meta-Analysis
Effects of Infant Formula Supplemented With Prebiotics on the Gut Microbiome, Gut Environment, Growth Parameters, and Safety and Tolerance: A Systematic Review and Meta-Analysis Open
Context Prebiotics are often added to infant formulas to mimic the benefits of oligosaccharides found in human milk. Objective This systematic review and meta-analysis evaluated the effects of prebiotic-supplemented cow’s milk–based formul…
View article: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake
Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake Open
Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes wit…
View article: Racial disparities in gestational weight gain and adverse pregnancy outcomes among Black and White pregnant people with obesity
Racial disparities in gestational weight gain and adverse pregnancy outcomes among Black and White pregnant people with obesity Open
Objective This study of pregnant people with obesity examined two aims in testing the hypothesis that the COVID‐19 pandemic widened racial disparity in maternal health in high‐risk pregnancies; it compared by race both (1) gestational weig…
View article: The role of government assistance, housing, and employment on postpartum maternal health across income and race: a mixed methods study
The role of government assistance, housing, and employment on postpartum maternal health across income and race: a mixed methods study Open
This research spotlights the negative impact of large-scale events most affected both Black and low-income individuals' postpartum mental health, and the role of government assistance, stable housing, and secure employment in helping to al…
View article: Metabolic scaling, energy allocation tradeoffs, and the evolution of humans’ unique metabolism
Metabolic scaling, energy allocation tradeoffs, and the evolution of humans’ unique metabolism Open
All organisms use limited energy to grow, survive, and reproduce, necessitating energy allocation tradeoffs, but there is debate over how selection impacted metabolic budgets and tradeoffs in primates, including humans. Here, we develop a …
View article: Energy expenditure, metabolic adaptation, physical activity and energy intake following weight loss: comparison between bariatric surgery and low-calorie diet
Energy expenditure, metabolic adaptation, physical activity and energy intake following weight loss: comparison between bariatric surgery and low-calorie diet Open
Bariatric surgery-induced weight loss decreased TDEE at 8 weeks and 1 year, resulting in metabolic adaptation after 8 weeks that was reversed at 1 year. These changes were accompanied by an increase in physical activity.
View article: Prediction of individual weight loss using supervised learning: findings from the CALERIETM 2 study
Prediction of individual weight loss using supervised learning: findings from the CALERIETM 2 study Open
The prediction models could be implemented by practitioners and clinicians to support the decision of whether lifestyle interventions are sufficient or more aggressive interventions are needed for a given individual, thereby supporting bet…
View article: Precision Interventions Targeting the Maternal Metabolic Milieu for Healthy Pregnancies in Obesity
Precision Interventions Targeting the Maternal Metabolic Milieu for Healthy Pregnancies in Obesity Open
View article: Precision Nutrition for Management of Cardiovascular Disease Risk During Menopause
Precision Nutrition for Management of Cardiovascular Disease Risk During Menopause Open
Background: Women can spend up to 40% of their lives in the postmenopausal state. As women begin to transition into menopause, known as perimenopause, changes in hormonal concentrations and body composition dramatically increase overall ca…