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View article: Ultra-processed food intake is associated with altered glucose homeostasis in young adults with a history of overweight or obesity: a longitudinal study
Ultra-processed food intake is associated with altered glucose homeostasis in young adults with a history of overweight or obesity: a longitudinal study Open
UPF consumption may increase the risk for T2D among young adults. Our findings suggest that limiting UPF consumption could be an important strategy for T2D prevention in this population.
Integrated Spheroid-to-Population Framework for Evaluating PFHpA-Associated Metabolic Dysfunction and Steatotic Liver Disease Open
The rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), particularly among pediatric populations, requires identification of modifiable risk factors to control disease progression. Per- and polyfluoroalky…
View article: Prenatal Diet and Infant Growth From Birth to Age 24 Months
Prenatal Diet and Infant Growth From Birth to Age 24 Months Open
Importance Being born either small for gestational age (SGA) or large for gestational age (LGA) and experiencing rapid or slow growth after birth are associated with later-life obesity. Understanding the associations of dietary quality dur…
View article: Childhood exposure to non-persistent endocrine disruptors, glucocorticosteroids, and attentional function: A cross-sectional study based on the parametric g-formula
Childhood exposure to non-persistent endocrine disruptors, glucocorticosteroids, and attentional function: A cross-sectional study based on the parametric g-formula Open
Our results suggest that multiple EDCs might interfere with inattention and with the homeostasis of the HPA axis.
View article: Machine learning-based health environmental-clinical risk scores in European children
Machine learning-based health environmental-clinical risk scores in European children Open
Background Early life environmental stressors play an important role in the development of multiple chronic disorders. Previous studies that used environmental risk scores (ERS) to assess the cumulative impact of environmental exposures on…
View article: Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children
Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children Open
Importance Prenatal exposure to ubiquitous endocrine-disrupting chemicals (EDCs) may increase the risk of metabolic syndrome (MetS) in children, but few studies have studied chemical mixtures or explored underlying protein and metabolic si…
View article: Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis Open
Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid function test …
Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study Open
Results suggest that beverage consumption habits and food preparation are associated with differences in PFAS levels in young adults. This highlights the importance of diet in determining PFAS exposure and the necessity of public monitorin…
View article: Common genetic variants associated with urinary phthalate levels in children: a genome-wide study
Common genetic variants associated with urinary phthalate levels in children: a genome-wide study Open
Introduction Phthalates, or dieters of phthalic acid, are a ubiquitous type of plasticizer used in a variety of common consumer and industrial products. They act as endocrine disruptors and are associated with increased risk for several di…
Beyond the single-outcome approach: A comparison of outcome-wide analysis methods for exposome research Open
Outcome-wide analysis can offer several benefits, including increased power to detect weak signals and the ability to identify exposures with multiple effects on health, which may be good targets for preventive measures. Recently, advanced…
Postprandial Metabolite Profiles and Risk of Prediabetes in Young People: A Longitudinal Multicohort Study Open
OBJECTIVE Prediabetes in young people is an emerging epidemic that disproportionately impacts Hispanic populations. We aimed to develop a metabolite-based prediction model for prediabetes in young people with overweight/obesity at risk for…
<b>Postprandial metabolite profiles </b><b>and risk of </b><b>prediabetes in young persons</b><b>: a longitudinal multi-cohort study</b> Open
Objective: Prediabetes in young persons is an emerging epidemic that disproportionately impacts Hispanic populations. We aimed to develop a metabolite-based prediction model for prediabetes in young persons with overweight/obesity at risk …