Explanipedia

Attention modulates hippocampal sharp-wave ripples in humans Open

Michał Domagała, Leila Chaieb, Charles E. Schroeder, Rainer Surges, Florian Mormann , et al. · 2025

Hippocampal sharp-wave ripples (SWRs) are high-frequency events critical for memory consolidation, typically studied during sleep and quiet wakefulness. Emerging evidence suggests that SWRs also occur during active behavior, yet their role…

Single‐Neuron Responses to Odor‐Related Words in the Human Amygdala Open

Marlene Derner, Leila Chaieb, Roy Cox, Valeri Borger · 2025

Human imaging studies suggest that visually presented words are processed by distributed networks beyond classical language areas, reflecting the properties related to their meanings. Based on human single‐neuron recordings, we investigate…

The role of mind wandering in memory consolidation: a status report Open

Leila Chaieb, Juergen Fell · 2025

Recent research has shown that memory consolidation (MC) is not only facilitated by sleep, in particular NREM sleep, but also by wakeful resting states. Mind wandering (MW) is a common phenomenon during waking state, especially during rest…

Hippocampal sharp wave ripples in human are modulated by attention Open

Michał Domagała, Leila Chaieb, Charles E. Schroeder, Rainer Surges, Florian Mormann , et al. · 2025

Side effects of monaural beat stimulation during sustained mental work on mind wandering and performance measures Open

Lucy Marlene Schmidt, Leila Chaieb, Marlene Derner, Thomas P. Reber, Juergen Fell · 2024

Excessive mind wandering (MW) contributes to the development and maintenance of psychiatric disorders. Previous studies have suggested that auditory beat stimulation may represent a method enabling a reduction of MW. However, little is kno…

Mind wandering in anxiety disorders: A status report Open

Juergen Fell, Leila Chaieb, Christian Hoppe · 2023

Many investigations have targeted the subject of worry in anxiety disorders. Worry can be regarded as a subtype of mind wandering (MW), which is undeliberate, perseverative, negatively-valenced, and mainly future-oriented. Nevertheless, un…

Auditory beat stimulation and behavioural variant of frontotemporal dementia: a case study Open

Leila Chaieb, Paweł Tacik, Michael T. Heneka, Juergen Fell · 2023

A growing number of studies suggest that auditory beat stimulation may be helpful in providing relief from symptoms of anxiety. However, evidence for this effect in clinical populations remains sparse. In this case study, we examined the e…

Modulation of Mind Wandering Using Monaural Beat Stimulation in Subjects With High Trait-Level Mind Wandering Open

Leila Chaieb, Sofie Krakau, Thomas P. Reber, Juergen Fell · 2022

Mind wandering (MW) refers to a state when attention shifts from the task at hand or current situation toward thoughts, feelings, and imaginations. This state is often accompanied by a decline in mood, and patients suffering from major dep…

On the relationship between mind wandering and mindfulness Open

Angelo Belardi, Leila Chaieb, Alodie Rey-Mermet, Florian Mormann, Nicolas Rothen , et al. · 2022

UCHL5 controls β-catenin destruction complex function through Axin1 regulation Open

Wonhee Han, Youngmu Koo, Leila Chaieb, Byeong‐Rak Keum, Jin‐Kwan Han · 2022

Mind wandering and depression: A status report Open

Leila Chaieb, Christian Hoppe, Juergen Fell · 2021

While many clinical studies and overviews on the contribution of rumination to depression exist, relatively little information regarding the role of mind wandering (MW) in general is available. Therefore, it remains an open question whethe…

On the Relationship between Mind Wandering and Mindfulness Open

Angelo Belardi, Leila Chaieb, Alodie Rey-Mermet, Florian Mormann, Nicolas Rothen , et al. · 2021

Mind wandering (MW) and mindfulness have both been reported to be vital moderators of psychological wellbeing. Here, we aim to examine how closely associated these phenomena are and evaluate the psychometrics of measures often used to quan…

Neural activity in the human anterior thalamus during natural vision Open

Marcin Leszczyński, Leila Chaieb, Tobias Staudigl, Simon Jonas Enkirch, Juergen Fell , et al. · 2021

Commentary: Mind-Wandering Changes in Dysphoria Open

Juergen Fell, Leila Chaieb · 2021

GENERAL COMMENTARY article Front. Psychiatry, 14 July 2021Sec. Mood Disorders https://doi.org/10.3389/fpsyt.2021.722819

Auditory Beat Stimulation Modulates Memory-Related Single-Neuron Activity in the Human Medial Temporal Lobe Open

Marlene Derner, Leila Chaieb, Gert Dehnen, Thomas P. Reber, Valeri Borger , et al. · 2021

Auditory beats are amplitude-modulated signals (monaural beats) or signals that subjectively cause the perception of an amplitude modulation (binaural beats). We investigated the effects of monaural and binaural 5 Hz beat stimulation on ne…

Low Intensity, Transcranial, Alternating Current Stimulation Reduces Migraine Attack Burden in a Home Application Set-Up: A Double-Blinded, Randomized Feasibility Study Open

Andrea Antal, Rebecca Bischoff, Caspar Stephani, Dirk Czesnik, Florian Klinker , et al. · 2020

Background: Low intensity, high-frequency transcranial alternating current stimulation (tACS) applied over the motor cortex decreases the amplitude of motor evoked potentials. This double-blind, placebo-controlled parallel group study aime…

Auditory beat stimulation modulates memory-related single-neuron activity in the human medial temporal lobe Open

Marlene Derner, Leila Chaieb, Gert Dehnen, TP Reber, Valeri Borger , et al. · 2020

Auditory beats are composed of two sine waves using nearby frequencies, which can either be applied as a superposed signal to both ears or to each ear separately. In the first case, the beat sensation results from hearing an amplitude-modu…

Patterns of single-neuron activity during associative recognition memory in the human medial temporal lobe Open

Marlene Derner, Gert Dehnen, Leila Chaieb, Thomas P. Reber, Valeri Borger , et al. · 2020

Electrophysiological activity in medial temporal lobe (MTL) structures is pivotal for declarative long-term memory. Single-neuron and microcircuit findings capitalizing on human microwire recordings from the medial temporal lobe are still …

Reduced past‐oriented mind wandering in left compared to right medial temporal lobe epilepsy Open

Sofie Krakau, Leila Chaieb, Christoph Helmstaedter, Randi von Wrede, Juergen Fell · 2020

Mind wandering refers to a shift of attention away from a task at hand to task‐unrelated thoughts. Several groups have shown increased activation of the left medial temporal lobe (MTL) before and during spontaneous thoughts suggesting that…

Eye movements modulate neural activity in the human anterior thalamus during visual active sensing Open

Marcin Leszczyński, Tobias Staudigl, Leila Chaieb, Simon Jonas Enkirch, Juergen Fell , et al. · 2020

Humans and other primates explore visual scenes by active sensing , using saccadic eye movements to relocate the fovea and sample different bits of information multiple times per second. Saccades induce a phase reset of ongoing neuronal os…

Author response for "Reduced past‐oriented mind wandering in left compared to right medial temporal lobe epilepsy" Open

Sofie Krakau, Leila Chaieb, Christoph Helmstaedter, Randi von Wrede, Juergen Fell · 2020

Eye movements modulate neural activity in the human anterior thalamus during visual active sensing Open

Marcin Leszczyński, Tobias Staudigl, Leila Chaieb, Simon Jonas Enkirch, Juergen Fell , et al. · 2020

New perspectives for the modulation of mind-wandering using transcranial electric brain stimulation Open

Leila Chaieb, Andrea Antal, Marlene Derner, Marcin Leszczyński, Juergen Fell · 2019

When our attention is decoupled from an ongoing task and becomes coupled to thoughts and feelings not being subject to task engagement, we are mind-wandering. This transient and pervasive mental process can occupy a considerable amount of …

Modulation of Item and Source Memory by Auditory Beat Stimulation: A Pilot Study With Intracranial EEG Open

Marlene Derner, Leila Chaieb, Rainer Surges, Bernhard P. Staresina, Juergen Fell · 2018

Auditory beat stimulation is an upcoming technique for non-invasive brain stimulation. Its influence on mediotemporal regions and memory processes has not yet been thoroughly investigated. A recent study suggests that auditory beats are ab…

Mind wandering simultaneously prolongs reactions and promotes creative incubation Open

Marcin Leszczyński, Leila Chaieb, Thomas P. Reber, Marlene Derner, Nikolai Axmacher , et al. · 2017

Mind wandering (MW) refers to the disengagement of attention from the external environment and the generation of thoughts unrelated to the task at hand. It is a ubiquitous cognitive process resulting in lapses of attention. MW imposes a ne…

The Impact of Monaural Beat Stimulation on Anxiety and Cognition Open

Leila Chaieb, Caroline Wilpert, Christian Hoppe, Nikolai Axmacher, Juergen Fell · 2017

Application of auditory beat stimulation has been speculated to provide a promising new tool with which to alleviate symptoms of anxiety and to enhance cognition. In spite of reportedly similar EEG effects of binaural and monaural beats, d…

Modulation of long-term memory using auditory beat stimulation Open

Leila Chaieb, Marlene Höhne, Bernhard P. Staresina, Christian E. Elger, Kevin G. Hampel , et al. · 2017

Memory encoding-related anterior hippocampal potentials are modulated by electric deep brain stimulation of the entorhinal area Open

Niels Hansen, Leila Chaieb, Bernhard P. Staresina, Kevin G. Hampel, Christian E. Elger , et al. · 2017

Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex Open

Leila Chaieb, Andrea Antal, Florentin Masurat, Walter Paulus · 2015

Near-infrared light stimulation of the brain has been claimed to improve deficits caused by traumatic brain injury and stroke. Here, we exploit the effect of transcranial near-infrared stimulation (tNIRS) as a tool to modulate cortical exc…

Prophylactic treatment in menstrual migraine: A proof-of-concept study Open

F. Wickmann, Caspar Stephani, Dirk Czesnik, Florian Klinker, Charles Timäus , et al. · 2015

The present study aimed to investigate the efficacy of repetitive cathodal direct current stimulation (rctDCS) over the visual cortex as a prophylactic treatment in patients with menstrual migraine. 20 female patients were recruited in thi…

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