Leiying Zhang
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View article: Biomechanical impact of hyperlipidemia on blood flow and vascular pressure: A computational and in vivo analysis
Biomechanical impact of hyperlipidemia on blood flow and vascular pressure: A computational and in vivo analysis Open
Hyperlipidemia is a major contributor to cardiovascular diseases, impacting vascular function by altering hemodynamic parameters such as blood flow velocity and vascular pressure. This study investigated these effects using Doppler ultraso…
View article: Knockdown of CENPM activates cGAS-STING pathway to inhibit ovarian cancer by promoting pyroptosis
Knockdown of CENPM activates cGAS-STING pathway to inhibit ovarian cancer by promoting pyroptosis Open
Objective We aimed to screen novel gene signatures for ovarian cancer (OC) and explore the role of biomarkers in OC via regulating pyroptosis using bioinformatics analysis. Methods Differentially expressed genes (DEGs) of OC were screened …
View article: Traboulsi syndrome: A case report
Traboulsi syndrome: A case report Open
View article: Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity
Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity Open
View article: Intrahepatic cholestasis of pregnancy can increase the risk of metabolic disorders: A meta-analysis
Intrahepatic cholestasis of pregnancy can increase the risk of metabolic disorders: A meta-analysis Open
Background: Gestational diabetes mellitus (GDM) and preeclampsia (PE) are common complications during pregnancy. Studies indicated that abnormal bile acid metabolism is related to its pathogenesis. Intrahepatic cholestasis of pregnancy (IC…
View article: The efficacy of therapeutic apheresis in patients with refractory neuromyelitis optica spectrum disorders: a single-center retrospective study
The efficacy of therapeutic apheresis in patients with refractory neuromyelitis optica spectrum disorders: a single-center retrospective study Open
Patients treated with LPE showed improved neurological function comparable to that reported with TPE treatment. No superiority was shown for either of the apheresis techniques.
View article: Changes in Complement Levels and Activity of Red Blood Cells, Fresh Frozen Plasma, and Platelet Concentrates During Storage
Changes in Complement Levels and Activity of Red Blood Cells, Fresh Frozen Plasma, and Platelet Concentrates During Storage Open
View article: Expression of Dual-Specificity Phosphatase 2 (DUSP2) in Patients with Serous Ovarian Carcinoma and in SKOV3 and OVCAR3 Cells In Vitro
Expression of Dual-Specificity Phosphatase 2 (DUSP2) in Patients with Serous Ovarian Carcinoma and in SKOV3 and OVCAR3 Cells In Vitro Open
BACKGROUND Ovarian cancer commonly presents at a late stage and is associated with poor prognosis. The most common histological subtype is serous ovarian carcinoma. Dual-specificity phosphatase 2 (DUSP2) is a protein phosphatase and substr…
View article: Induction of Pluripotent Stem Cell-Derived Cardiomyocyte Toxicity by Supernatant of Long Term-Stored Red Blood Cells in Vitro
Induction of Pluripotent Stem Cell-Derived Cardiomyocyte Toxicity by Supernatant of Long Term-Stored Red Blood Cells in Vitro Open
Background/Aims: Preserved red blood cells (RBCs) in vitro undergo a series of morphological, functional and metabolic changes during storage. RBC metabolites accumulate over time during storage, the toxicity of the supernatants of RBCs (S…
View article: Red Blood Cell Transfusion and Functional Dose
Red Blood Cell Transfusion and Functional Dose Open
Objective:The objective is to study the relationship between cell age and function in the process of the red blood cell (RBC) normal metabolism and investigate the functional changes of red blood cells in the preservation process.