Lena E. Winestone
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View article: Survival after first relapse of pediatric B-ALL differs by insurance type: A real-world analysis from the recall-1 study
Survival after first relapse of pediatric B-ALL differs by insurance type: A real-world analysis from the recall-1 study Open
BACKGROUND Children exposed to poverty during frontline therapy for B-lymphoblastic leukemia (B-ALL) experience inferior overall survival (OS), higher relapse rates, and earlier relapse than their peers. Real-world data describing treatmen…
View article: Table S1 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S1 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia Genomic Subtype Description.
View article: Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestries (25% Interval) as Continuous Variables with Pathway Alteration using Logistic Regression Models for Each Pathway.
View article: Table S2 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S2 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia subtype by Categorical Genetic Ancestry
View article: Table S10 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S10 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Detailed clinical data
View article: Table S6 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S6 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestry (25% interval) as Continuous Variables with Survival Outcomes.
View article: Table S9 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S9 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of NOTCH pathway alteration with Survival Outcomes stratified by categorical genetic ancestry.
View article: Table S3 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S3 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestries (25% Interval) as Continuous Variables with Biologic Subtype (TAL1 DP-like as reference subtype) Using Multinomial Regression Model.
View article: Table S7 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S7 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Types of Reported Events by Genetic Ancestry.
View article: Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia Pathway Alterations by Categorical Genetic Ancestry
View article: Supplementary Figures S1-S11 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Supplementary Figures S1-S11 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Supplementary Figure S1. T-ALL subtype classifying driver genes among individuals of European, Admixed American, and African ancestry. Supplementary Figure S2. T-ALL subtype classifying driver genes among patients with Early T-cell Precurs…
View article: Table S8 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S8 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Frequency of Genetic Alterations of Genes in the NOTCH Pathway by Ancestry.
View article: Lower Neighborhood Socioeconomic Status Is Associated With Intensive Care Unit Admission at Initial Presentation in Children With Acute Leukemia
Lower Neighborhood Socioeconomic Status Is Associated With Intensive Care Unit Admission at Initial Presentation in Children With Acute Leukemia Open
Background Lower socioeconomic status (SES) and minority race and ethnicity are associated with lower overall survival in pediatric leukemia. Higher acuity at initial presentation is associated with mortality during induction chemotherapy.…
View article: Supplementary Figures S1-S11 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Supplementary Figures S1-S11 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Supplementary Figure S1. T-ALL subtype classifying driver genes among individuals of European, Admixed American, and African ancestry. Supplementary Figure S2. T-ALL subtype classifying driver genes among patients with Early T-cell Precurs…
View article: Table S2 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S2 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia subtype by Categorical Genetic Ancestry
View article: Table S7 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S7 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Types of Reported Events by Genetic Ancestry.
View article: Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S4 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia Pathway Alterations by Categorical Genetic Ancestry
View article: Data from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Data from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
The influence of genetic ancestry on genomics in T-cell acute lymphoblastic leukemia (T-ALL) has not been fully explored. We examined the impact of genetic ancestry on multiomic alterations, survival outcomes, and risk stratification. Amon…
View article: Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S5 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestries (25% Interval) as Continuous Variables with Pathway Alteration using Logistic Regression Models for Each Pathway.
View article: Table S8 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S8 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Frequency of Genetic Alterations of Genes in the NOTCH Pathway by Ancestry.
View article: Table S1 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S1 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
T-cell Acute Lymphoblastic Leukemia Genomic Subtype Description.
View article: Table S6 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S6 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestry (25% interval) as Continuous Variables with Survival Outcomes.
View article: Table S3 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S3 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of Genetic Ancestries (25% Interval) as Continuous Variables with Biologic Subtype (TAL1 DP-like as reference subtype) Using Multinomial Regression Model.
View article: Table S9 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S9 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Association of NOTCH pathway alteration with Survival Outcomes stratified by categorical genetic ancestry.
View article: Table S10 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia
Table S10 from Impact of Genetic Ancestry on Genomics and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia Open
Detailed clinical data
View article: Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children’s Oncology Group report
Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children’s Oncology Group report Open
Pediatric Hispanic and Black patients with newly diagnosed B-cell acute lymphoblastic leukemia (B-ALL) experience worse overall survival (OS). We hypothesized that differential outcomes by race and ethnicity following relapse may contribut…
View article: Real-world outcomes of infections following tisagenlecleucel in patients with B-cell ALL: a CIBMTR analysis
Real-world outcomes of infections following tisagenlecleucel in patients with B-cell ALL: a CIBMTR analysis Open
Tisagenlecleucel (tisa-cel) is a CD19-directed chimeric antigen receptor T-cell therapy for relapsed/refractory precursor B-cell acute lymphoblastic leukemia (R/R B-ALL). We report infectious complications for 100 days (D100) following tis…
View article: Impact of neighborhood archetypes on overall mortality among young patients with acute leukemia in California
Impact of neighborhood archetypes on overall mortality among young patients with acute leukemia in California Open
Introduction Residence in lower socioeconomic neighborhoods is associated with lower survival in children, adolescents, and young adults with leukemia. We sought to evaluate the impact of neighborhood archetypes on acute lymphoblastic leuk…
View article: High Melphalan Exposure Increases the Risk of Graft-Versus-Host Disease in Pediatric Patients Undergoing Alpha-Beta T-Cell Depleted Haploidentical Transplantation
High Melphalan Exposure Increases the Risk of Graft-Versus-Host Disease in Pediatric Patients Undergoing Alpha-Beta T-Cell Depleted Haploidentical Transplantation Open
High melphalan exposure predicted by a validated population PK model is associated with an increased likelihood of developing ES and subsequently acute and chronic GVHD. Given that a substantial number of patients already require adjustmen…