Leon Botes
YOU?
Author Swipe
View article: ‘I don’t think I really realised how different the ‘new normal’ would be’—a qualitative study with cancer survivors to inform the development of survivorship centres
‘I don’t think I really realised how different the ‘new normal’ would be’—a qualitative study with cancer survivors to inform the development of survivorship centres Open
Many people experience a wide range of health and wellbeing issues after cancer, which could be addressed by various supportive care services. The purpose of this study was to identify the needs of cancer survivors and carers by exploring …
View article: Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in <i>BRCA1</i> and <i>BRCA2</i>
Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in <i>BRCA1</i> and <i>BRCA2</i> Open
PURPOSE It is uncertain whether, and to what extent, hormonal contraceptives increase breast cancer (BC) risk for germline BRCA1 or BRCA2 mutation carriers. METHODS Using pooled observational data from four prospective cohort studies, asso…
View article: Pregnancy-Related Factors and Breast Cancer Risk for Women Across a Range of Familial Risk
Pregnancy-Related Factors and Breast Cancer Risk for Women Across a Range of Familial Risk Open
Importance Few studies have investigated whether the associations between pregnancy-related factors and breast cancer (BC) risk differ by underlying BC susceptibility. Evidence regarding variation in BC risk is critical to understanding BC…
View article: Cancer Risks Associated With <i>TP53</i> Pathogenic Variants: Maximum Likelihood Analysis of Extended Pedigrees for Diagnosis of First Cancers Beyond the Li-Fraumeni Syndrome Spectrum
Cancer Risks Associated With <i>TP53</i> Pathogenic Variants: Maximum Likelihood Analysis of Extended Pedigrees for Diagnosis of First Cancers Beyond the Li-Fraumeni Syndrome Spectrum Open
PURPOSE Establishing accurate age-related penetrance figures for the broad range of cancer types that occur in individuals harboring a pathogenic germline variant in the TP53 gene is essential to determine the most effective clinical manag…