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View article: Développement de modèles hybrides pour les réseaux métaboliques à l'échelle du génome
Développement de modèles hybrides pour les réseaux métaboliques à l'échelle du génome Open
Over the past two decades, the systems biology community has dedicated substantial efforts to constructing genome-scale metabolic models (GEMs), which offer detailed representations of an organism's entire metabolism. GEMs present metaboli…
View article: A neural-mechanistic hybrid approach improving the predictive power of genome-scale metabolic models
A neural-mechanistic hybrid approach improving the predictive power of genome-scale metabolic models Open
Constraint-based metabolic models have been used for decades to predict the phenotype of microorganisms in different environments. However, quantitative predictions are limited unless labor-intensive measurements of media uptake fluxes are…
View article: A versatile active learning workflow for optimization of genetic and metabolic networks
A versatile active learning workflow for optimization of genetic and metabolic networks Open
The study, engineering and application of biological networks require practical and efficient approaches. Current optimization efforts of these systems are often limited by wet lab labor and cost, as well as the lack of convenient, easily …
View article: Galaxy-SynBioCAD: Synthetic Biology Design Automation tools in Galaxy workflows
Galaxy-SynBioCAD: Synthetic Biology Design Automation tools in Galaxy workflows Open
Many computer-aided design tools are available for synthetic biology and metabolic engineering. Yet, these tools can be difficult to apprehend, sometimes requiring a level of expertise that limits their use by a wider community. Furthermor…
View article: Energy-Flow in bacterial growth
Energy-Flow in bacterial growth Open
We are replicating an experiment about energy flow in E. coli.