Leon Lufkin
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View article: Nonlinear dynamics of localization in neural receptive fields
Nonlinear dynamics of localization in neural receptive fields Open
Localized receptive fields -- neurons that are selective for certain contiguous spatiotemporal features of their input -- populate early sensory regions of the mammalian brain. Unsupervised learning algorithms that optimize explicit sparsi…
View article: Sharp Information-Theoretic Thresholds for Shuffled Linear Regression
Sharp Information-Theoretic Thresholds for Shuffled Linear Regression Open
This paper studies the problem of shuffled linear regression, where the correspondence between predictors and responses in a linear model is obfuscated by a latent permutation. Specifically, we consider the model $y = Π_* X β_* + w$, where…
View article: A stronger association of depression with rheumatoid arthritis in presence of obesity and hypertriglyceridemia
A stronger association of depression with rheumatoid arthritis in presence of obesity and hypertriglyceridemia Open
Background Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic and systemic inflammation. Recent research underscores the role of chronic inflammation in multiple common RA comorbidities such as depression, obesity…
View article: A stronger association of depression with rheumatoid arthritis in presence of obesity and hypertriglyceridemia
A stronger association of depression with rheumatoid arthritis in presence of obesity and hypertriglyceridemia Open
Background Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic and systemic inflammation. Recent research underscores the role of chronic inflammation in multiple common RA comorbidities such as depression, obesity…
View article: Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival
Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival Open
Regenerative medicine aims to repair degenerate tissue through cell refurbishment with minimally invasive procedures. Adipose tissue (FAT)-derived stem or stromal cells are a convenient autologous choice for many regenerative cell therapy …
View article: Emergent organization of receptive fields in networks of excitatory and inhibitory neurons
Emergent organization of receptive fields in networks of excitatory and inhibitory neurons Open
Local patterns of excitation and inhibition that can generate neural waves are studied as a computational mechanism underlying the organization of neuronal tunings. Sparse coding algorithms based on networks of excitatory and inhibitory ne…
View article: A Bayesian Model to Analyze the Association of Rheumatoid Arthritis With Risk Factors and Their Interactions
A Bayesian Model to Analyze the Association of Rheumatoid Arthritis With Risk Factors and Their Interactions Open
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that commonly manifests as destructive joint inflammation but also affects multiple other organ systems. The pathogenesis of RA is complex where a variety of factors including como…
View article: A Bayesian Model for Prediction of Rheumatoid Arthritis from Risk Factors
A Bayesian Model for Prediction of Rheumatoid Arthritis from Risk Factors Open
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that typically manifests as destructive joint inflammation but also affects multiple other organ systems. The pathogenesis of RA is complex where a variety of factors including com…