Leona Berndt
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View article: Insights into a water-mediated catalytic triad architecture in CE20 carbohydrate esterases
Insights into a water-mediated catalytic triad architecture in CE20 carbohydrate esterases Open
View article: Reprogramming of bacterial virulence by lysine acetylation
Reprogramming of bacterial virulence by lysine acetylation Open
Gram-negative bacteria use a plethora of virulence factors to infect eukaryotic cells. CE-clan protease-related virulence factors were reported to act as deubiquitinases/ubiquitin-like specific proteases. Some have an additional acetyltran…
View article: Marine <i>Bacteroidetes</i> enzymatically digest xylans from terrestrial plants
Marine <i>Bacteroidetes</i> enzymatically digest xylans from terrestrial plants Open
Marine Bacteroidetes that degrade polysaccharides contribute to carbon cycling in the ocean. Organic matter, including glycans from terrestrial plants, might enter the oceans through rivers. Whether marine bacteria degrade structurally rel…
View article: Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus
Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus Open
The bacterial chalcone isomerase (CHI) from Eubacterium ramulus catalyses the first step in a flavanone-degradation pathway by a reverse Michael addition. The overall fold and the constitution of the active site of the enzyme completely di…
View article: Diversification by CofC and Control by CofD Govern Biosynthesis and Evolution of Coenzyme F <sub>420</sub> and Its Derivative 3PG-F <sub>420</sub>
Diversification by CofC and Control by CofD Govern Biosynthesis and Evolution of Coenzyme F <sub>420</sub> and Its Derivative 3PG-F <sub>420</sub> Open
The microbial cofactor F 420 is crucial for processes like methanogenesis, antibiotics biosynthesis, drug resistance, and biocatalysis. Recently, a novel derivative of F 420 (3PG-F 420 ) was discovered, enabling the production and use of F…
View article: Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F<sub>420</sub> and its derivative 3PG-F<sub>420</sub>
Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F<sub>420</sub> and its derivative 3PG-F<sub>420</sub> Open
Coenzyme F 420 is a microbial redox cofactor that is increasingly used for biocatalytic applications. Recently, diversified biosynthetic routes to F 420 and the discovery of a derivative, 3PG-F 420 , were reported. 3PG-F 420 is formed via …
View article: Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate Open
View article: Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9
Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9 Open
In flowering plant plastids and mitochondria, multiple organellar RNA editing factor (MORF/RIP) proteins are required at most sites for efficient C to U RNA editing catalyzed by the RNA editosome. MORF proteins harbor a conserved stretch o…