Leonard T. Nguyen
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View article: Seropositivity to SARS-CoV-2 in Alberta, Canada in a post-vaccination period (March 2021–July 2021)
Seropositivity to SARS-CoV-2 in Alberta, Canada in a post-vaccination period (March 2021–July 2021) Open
Longitudinal surveillance of SARS-CoV-2 seropositivity with data linkage is valuable for decision-making during the pandemic.
View article: Pre-Vaccine Positivity of SARS-CoV-2 Antibodies in Alberta, Canada during the First Two Waves of the COVID-19 Pandemic
Pre-Vaccine Positivity of SARS-CoV-2 Antibodies in Alberta, Canada during the First Two Waves of the COVID-19 Pandemic Open
Using SARS-CoV-2 serology testing, we assessed the proportion of people in Alberta, Canada (population 4.4 million) positive for COVID-19 antibodies, indicating previous infection, during the first two waves of the COVID-19 pandemic (prior…
View article: Factors Associated with Hyponatremia in Patients Newly Prescribed Citalopram: A Retrospective Observational Study
Factors Associated with Hyponatremia in Patients Newly Prescribed Citalopram: A Retrospective Observational Study Open
View article: Title Assessing Potentially Inappropriate Medications in Seniors: Differences between American Geriatrics Society and STOPP Criteria, and Preventing Adverse Drug Reactions
Title Assessing Potentially Inappropriate Medications in Seniors: Differences between American Geriatrics Society and STOPP Criteria, and Preventing Adverse Drug Reactions Open
Key problems for seniors are their exposure to “potentially inappropriate medications” and “potential medication omissions”, which place them at risk for moderate, severe, or fatal adverse drug reactions. This study of 82,935 first admissi…
View article: Potentially Inappropriate Prescribing and Potential Prescribing Omissions in 82,935 Older Hospitalised Adults: Association with Hospital Readmission and Mortality within Six Months
Potentially Inappropriate Prescribing and Potential Prescribing Omissions in 82,935 Older Hospitalised Adults: Association with Hospital Readmission and Mortality within Six Months Open
Polypharmacy with “potentially inappropriate medications” (PIMs) and “potential prescribing omissions” (PPOs) are frequent among those 65 and older. We assessed PIMs and PPOs in a retrospective study of 82,935 patients ≥ 65 during their fi…
View article: Dataset of clinical laboratory tests according to ordering variance among family physicians in Calgary, Alberta, Canada
Dataset of clinical laboratory tests according to ordering variance among family physicians in Calgary, Alberta, Canada Open
View article: Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada
Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada Open
View article: Expression and Purification of Chemokine MIP-3α (CCL20) through a Calmodulin-Fusion Protein System
Expression and Purification of Chemokine MIP-3α (CCL20) through a Calmodulin-Fusion Protein System Open
Human macrophage inflammatory protein 3α (MIP-3α), also known as CCL20, is a 70 amino acid chemokine that selectively binds and activates chemokine receptor 6 (CCR6). This chemokine is responsible for inducing the migration of immature den…
View article: Incidence of chronic myeloid leukemia in Calgary, Alberta, Canada
Incidence of chronic myeloid leukemia in Calgary, Alberta, Canada Open
View article: Incidence of Myelodysplastic Syndromes in a Major Canadian Metropolitan Area
Incidence of Myelodysplastic Syndromes in a Major Canadian Metropolitan Area Open
Background Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders that can progress to acute myeloid leukemia. In many regions of the world, the epidemiology of MDS is poorly described. This study determine…
View article: Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study Open
View article: The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study
The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study Open
View article: Sociodemographic Correlates of Clinical Laboratory Test Expenditures in a Major Canadian City
Sociodemographic Correlates of Clinical Laboratory Test Expenditures in a Major Canadian City Open
There is variation in testing costs for patients among different sociodemographic variables.
View article: Structural and dynamic characterization of a freestanding acyl carrier protein involved in the biosynthesis of cyclic lipopeptide antibiotics
Structural and dynamic characterization of a freestanding acyl carrier protein involved in the biosynthesis of cyclic lipopeptide antibiotics Open
Friulimicin is a cyclic lipodecapeptide antibiotic that is produced by Actinoplanes friuliensis . Similar to the related lipopeptide drug daptomycin, the peptide skeleton of friulimicin is synthesized by a large multienzyme nonribosomal pe…
View article: Staphylokinase has distinct modes of interaction with antimicrobial peptides, modulating its plasminogen-activation properties
Staphylokinase has distinct modes of interaction with antimicrobial peptides, modulating its plasminogen-activation properties Open