Leonid I. Bubman
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View article: Comparative methods of sarcopenia diagnostics in geriatric practice
Comparative methods of sarcopenia diagnostics in geriatric practice Open
INTRODUCTION. One of the key processes that inevitably accompany aging is considered to be a variety of changes in body composition. As we age, lean tissue components (in particular, skeletal muscles) decrease, while the content of adipose…
View article: Subclinical inflammation in very old and long-living patients with coronary artery disease
Subclinical inflammation in very old and long-living patients with coronary artery disease Open
BACKGROUND . With aging, the concentration of proinflammatory mediators increases even in the absence of signs of inflammation (“inflammaging”). AIM. To determine the serum concentration of tumor necrosis factor-alpha (TNF-α) and interleuk…
View article: Body composition in long-living patients: sarcopenia, obesity and osteoporosis
Body composition in long-living patients: sarcopenia, obesity and osteoporosis Open
BACKGROUND . Studies on body composition in long-living patients, especially using dual-energy absorptiometry, are almost unknown. AIM. To investigate body composition in patients over 90 years old (long-living patients) with coronary arte…
View article: Leptin in very old and long-living patients with coronary artery disease
Leptin in very old and long-living patients with coronary artery disease Open
BACKGROUND . Leptin is involved in the development of some age-related pathological conditions, in particular, metabolic syndrome, obesity, diabetes mellitus and atherosclerosis. Considering the population aging and high prevalence of card…
View article: Laboratory markers of inflammatory activity in patients with combat limb injuries
Laboratory markers of inflammatory activity in patients with combat limb injuries Open
The study aim – to investigate laboratory markers of inflammatory activity (C-reactive protein, ESR, leukocytes and leukocyte indices, interleukin-6 and ferritin) in patients with combat limb injuries. Materials and methods. The prospectiv…
View article: Local negative pressure wound therapy in patients with combat limb injuries: one-center experience
Local negative pressure wound therapy in patients with combat limb injuries: one-center experience Open
Objective . To study the effectiveness and safety of negative pressure wound therapy in patients with combat limb injuries. Material and methods . 248 patients who suffered of combat injuries of lower and/or upper extremities for 4–58 days…
View article: Venous thromboembolic complications in wounded with combat-related extremity injuries
Venous thromboembolic complications in wounded with combat-related extremity injuries Open
Цель исследования: изучить частоту и характер венозных тромбоэмболических осложнений (ВТЭО) у пациентов с боевыми ранениями конечностей. Материалы и методы. В проспективное наблюдательное исследование включены 290 пациентов, перенесших ран…
View article: Negative pressure wound therapy in patients with combat limb injuries: literature review
Negative pressure wound therapy in patients with combat limb injuries: literature review Open
The review reflects modern vision about combat injuries. Particular attention is paid to injuries of the extremities and methods of their treatment. Despite advances in surgical techniques and medical technology, treating extremity combat …
View article: Hyperglycemia in patients with combat injuries
Hyperglycemia in patients with combat injuries Open
Aim. To investigate the prevalence and some aspects of the carbohydrate metabolism pathology in patients with combat limb injuries. Materials and methods. 210 patients who suffered from combat injuries of the lower and/or upper extremities…
View article: Heart rhythm disturbances and blood pressure profile in patients with combat injuries
Heart rhythm disturbances and blood pressure profile in patients with combat injuries Open
Aim. To investigate possible rhythm and conduction disturbances, as well as the blood pressure (BP) profile in young and middle-aged patients with combat wounds. Materials and methods. The cross-sectional study enrolled 102 patients who su…
View article: Microbial landscape of wounds in patients with combat trauma of extremities
Microbial landscape of wounds in patients with combat trauma of extremities Open
Objective. To analyze the profile of bacterial pathogens in patients with extremities wounds resulting from mine-blast injuries, and their susceptibility to antibacterial drugs. Materials and methods. The prospective observational study en…
View article: Osteoporosis and body composition in old patients with amputated lower limbs
Osteoporosis and body composition in old patients with amputated lower limbs Open
The study aim was to investigate bone mineral density (BMD) and body composition in old patients with amputated lower limbs. Materials and methods . This work is a cross-sectional study, which enrolled 31 patients, who underwent amputation…
View article: Microbial landscape of pressure ulcers in patients with severe injuries of the central nervous system
Microbial landscape of pressure ulcers in patients with severe injuries of the central nervous system Open
Research goal. To investigate the incidence of pressure ulcers and the structure of bacterial pathogens in young patients who have suffered severe trauma to the brain or spinal cord. Materials and methods. The prospective observational stu…
View article: «Locomotive syndrome» in patients in the geriatric hospital
«Locomotive syndrome» in patients in the geriatric hospital Open
The study aim was to analyze the prevalence and course of locomotive syndrome in patients in the geriatric hospital. Materials and methods. This work was a cross-sectional study performed on the basis of the Moscow War Veterans Hospital N3…
View article: Hematological indices – a new marker of inflammation in old patients and centenarians with trophic ulcers of lower extremities
Hematological indices – a new marker of inflammation in old patients and centenarians with trophic ulcers of lower extremities Open
Aim. To study the significance of various hematological indices as markers of laboratory inflammatory activity in patients with trophic ulcers of the lower extremities and compare them with similar indices in old patients with coronary art…
View article: Interleukin-6 in old patients with trophic ulcers of the lower extremities
Interleukin-6 in old patients with trophic ulcers of the lower extremities Open
Aim. To study the pathogenetic role of interleukin-6 (IL-6) in old patients with trophic ulcers of the lower extremities. Methods. The study enrolled 66 patients suffered from trophic ulcers of the lower extremities. The mean age of study …
View article: VITAMIN D IN VARIOUS AGE-RELATED PATHOLOGY IN CENTENARIANS AND VERY ELDERLY PATIENTS WITH CORONARY ARTERY DISEASE
VITAMIN D IN VARIOUS AGE-RELATED PATHOLOGY IN CENTENARIANS AND VERY ELDERLY PATIENTS WITH CORONARY ARTERY DISEASE Open
Introduction. Vitamin D deficiency is associated with many pathological conditions. The elderly is at high risk of vitamin D deficiency due to their reduced ability to produce vitamin D precursors in the skin. Aim. To analyze 25-Hydroxycal…
View article: INTERLEUKIN-6 – MARKER OF SUBCLINICAL INFLAMMATION IN VERY ELDERLY PATIENTS AND CENTENARIANS WITH CORONARY ARTERY DISEASE
INTERLEUKIN-6 – MARKER OF SUBCLINICAL INFLAMMATION IN VERY ELDERLY PATIENTS AND CENTENARIANS WITH CORONARY ARTERY DISEASE Open
Introduction. Interleukin-6 is a cytokine involved in the regulation of immune reactions, in the processes of hematopoiesis and inflammation. Levels of interleukin-6 in the blood correlate with the development of senile asthenia. Aim. The …
View article: Trophic ulcers of the lower extremities in centenarians: are there any features?
Trophic ulcers of the lower extremities in centenarians: are there any features? Open
Aim. To compare various clinical and laboratory parameters in centenarians and old patients with trophic ulcers of the lower extremities. Materials and methods. 100 patients were enrolled in the cross-sectional study; 45 centenarians with …
View article: Thyroid hormones in centenarians in coronary artery disease
Thyroid hormones in centenarians in coronary artery disease Open
Aim. To analyze the relationship of thyroid hormones with various clinical and laboratory parameters in centenarians with coronary artery disease (CAD) based on the determination of the blood concentration of thyroid-stimulating hormone (T…
View article: Calcium and osteoporosis in old and very old patients with coronary artery disease
Calcium and osteoporosis in old and very old patients with coronary artery disease Open
im. To analyze the relationship between calcium and various clinical and laboratory parameters in old and very old patients with coronary artery disease (CAD) based on the determination of the blood concentration of ionized calcium and dai…
View article: Hematological indices – a possible marker of subclinical inflammation in very elderly patients and centenarians
Hematological indices – a possible marker of subclinical inflammation in very elderly patients and centenarians Open
Aim. To study the possibility of using hematological indices as markers of subclinical inflammation in very elderly patients and centenarians with coronary artery disease (CAD). Materials and Methods: The cross-sectional study enrolled 127…
View article: Bilateral internal carotid artery occlusion: case report
Bilateral internal carotid artery occlusion: case report Open