Liang Kang
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View article: Dynamic Arginine Methylation of YBX1 Relay Controls Its Phase Separation and Chemoradiotherapy Resistance in Rectal Cancer
Dynamic Arginine Methylation of YBX1 Relay Controls Its Phase Separation and Chemoradiotherapy Resistance in Rectal Cancer Open
Although neoadjuvant chemoradiotherapy is the standard treatment and significantly improves prognosis of locally advanced rectal cancer, patients may develop primary or secondary therapy resistance. Here, through functional screening, we i…
View article: Efficient Parallel Computing Algorithms for Robotic Manipulator Kinematics
Efficient Parallel Computing Algorithms for Robotic Manipulator Kinematics Open
A method for compiling object schemes is proposed, which allows constructing algorithms for calculating the kinematic parameters of robotic manipulators. Examples of compiling object schemes for calculating the velocities and accelerations…
View article: Neoadjuvant treatment of IBI310 plus sintilimab in locally advanced MSI-H/dMMR colon cancer: A randomized phase 1b study
Neoadjuvant treatment of IBI310 plus sintilimab in locally advanced MSI-H/dMMR colon cancer: A randomized phase 1b study Open
Although neoadjuvant immunotherapy showed promising efficacy in locally advanced microsatellite instability-high or mismatch repair-deficient (MSI-H/dMMR) colon cancer, whether dual immune checkpoint inhibition provides additional benefit …
View article: Phosphorylation of KIAA1429 promotes oxaliplatin resistance through activating the FZD7-Wnt signaling in BRAFV600E-mutated colorectal cancer
Phosphorylation of KIAA1429 promotes oxaliplatin resistance through activating the FZD7-Wnt signaling in BRAFV600E-mutated colorectal cancer Open
Background The current standard therapeutic approach for colorectal cancer (CRC) is surgical operation and oxaliplatin (OXA)-based neoadjuvant chemotherapy. However, the acquisition of oxaliplatin resistance leads to an unfavorable prognos…
View article: Effects of gut microbiota in breast cancer
Effects of gut microbiota in breast cancer Open
Breast cancer (BC) stands as the predominant form of cancer affecting women globally, with its etiology rooted in a complex interplay of factors. Emerging research underscores the significant impact of microbiota on the development of BC. …
View article: Semantic-Aware Visual Information Transmission With Key Information Extraction Over Wireless Networks
Semantic-Aware Visual Information Transmission With Key Information Extraction Over Wireless Networks Open
The advent of 6G networks demands unprecedented levels of intelligence, adaptability, and efficiency to address challenges such as ultra-high-speed data transmission, ultra-low latency, and massive connectivity in dynamic environments. Tra…
View article: Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer
Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer Open
Importance Previous studies have demonstrated the advantages of short-term histopathological outcomes and complications associated with transanal total mesorectal excision (TME) compared with laparoscopic TME. However, the long-term oncolo…
View article: Angptl3 Promotes Colorectal Carcinoma Progression and Metastasis Through Regulating Col1a2 Transcription Via Interacting with Integrin Αvβ3
Angptl3 Promotes Colorectal Carcinoma Progression and Metastasis Through Regulating Col1a2 Transcription Via Interacting with Integrin Αvβ3 Open
View article: Transanal endoscopic local resection versus radical excision in the treatment of massive rectal gastrointestinal stromal tumors: striving for therapeutic advantages
Transanal endoscopic local resection versus radical excision in the treatment of massive rectal gastrointestinal stromal tumors: striving for therapeutic advantages Open
Objectives: To compare the therapeutic advantages of transanal endoscopic local resection (taLR) and transabdominal radical resection (tbRR) in the treatment of massive gastrointestinal stromal tumors (GIST). Design: Single-center retrospe…
View article: Artificial Intelligence-Based Algorithm for Pathological Response Assessment to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Multi-Center Derived Platform Can Shrink a Mountainous Task into a Molehill
Artificial Intelligence-Based Algorithm for Pathological Response Assessment to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Multi-Center Derived Platform Can Shrink a Mountainous Task into a Molehill Open
View article: Effect of Baduanjin exercise on acute myocardial infarction in patients with anxiety and depression after percutaneous coronary intervention: A randomized controlled trial
Effect of Baduanjin exercise on acute myocardial infarction in patients with anxiety and depression after percutaneous coronary intervention: A randomized controlled trial Open
Background: Acute myocardial infarction (AMI) is the most severe type of coronary heart disease and patients often require percutaneous coronary intervention (PCI). However, anxiety and depression are common complications of PCI. Methods: …
View article: Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Materials were used in the research.
View article: Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 exerts an immunomodulatory effect through YTHDF2-CXCL10 axis.
View article: Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 expression is positively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 is highly expressed in CRC tissues compared to tumor-adjacent tissue regardless of MMR status.
View article: Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
CXCL10 is indispensable for KRT7-mediated improved responsiveness to ICIs.
View article: Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
YTHDF2 expression is negatively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 1 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 is highly expressed in CRC tissues compared to tumor-adjacent tissue regardless of MMR status.
View article: Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Detailed descriptions of supplementary figures.
View article: Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 5-7 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
YTHDF2 expression is negatively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Legends from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Detailed descriptions of supplementary figures.
View article: Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 3-4 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 expression is positively correlated with CD3+ and CD8+ densities in tumor parenchyma and invasive margin in CRC.
View article: Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 has no effect on proliferation, migration and invasion of CRC cells.
View article: Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 8 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 exerts an immunomodulatory effect through YTHDF2-CXCL10 axis.
View article: Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 9 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
CXCL10 is indispensable for KRT7-mediated improved responsiveness to ICIs.
View article: Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Fig. 2 from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
KRT17 has no effect on proliferation, migration and invasion of CRC cells.
View article: Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer
Supplementary Tables from KRT17 promotes T-lymphocyte infiltration through the YTHDF2-CXCL10 axis in colorectal cancer Open
Materials were used in the research.
View article: Postoperative urinary retention following transanal versus laparoscopic total mesorectal excision for rectal cancer: A randomized trial report from an experienced center
Postoperative urinary retention following transanal versus laparoscopic total mesorectal excision for rectal cancer: A randomized trial report from an experienced center Open
Background: Transanal total mesorectal excision has emerged as a potential solution to certain limitations associated with laparoscopic total mesorectal excision in rectal cancer patients. Differences in surgical approaches have raised que…
View article: The treatment efficacy for Patients Undergoing Combined Transanal-Transabdominal Endoscopic Resection of Colorectal Anastomosis Stenosis
The treatment efficacy for Patients Undergoing Combined Transanal-Transabdominal Endoscopic Resection of Colorectal Anastomosis Stenosis Open
Background: Combined transanal- transabdominal resection of anastomotic stenosis has the potential to restore bowel continuity for patients with instead of suffered colorectal anastomosis stenosis. The objective of this study was to assess…
View article: Knowledge domain and emerging trends in anxiety and depression after myocardial infarction research during 2002–2022: Bibliometric and visualized analysis
Knowledge domain and emerging trends in anxiety and depression after myocardial infarction research during 2002–2022: Bibliometric and visualized analysis Open