Lesley Trask
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View article: Mechanotherapy: Modulating immune cell function in tissue regeneration and fibrosis
Mechanotherapy: Modulating immune cell function in tissue regeneration and fibrosis Open
Mechanotherapy - therapy which uses mechanical forces to produce a remedial or prophylactic effect - has great potential to improve therapeutic outcomes in the fields of regenerative medicine and drug delivery due to its adaptable and tuna…
View article: Exploring therapy transport from implantable medical devices using experimentally informed computational methods
Exploring therapy transport from implantable medical devices using experimentally informed computational methods Open
An experimentally informed device model capturing reduced factor transport resulting from the fibrous capsule (FC) and recovered using fluid flow.
View article: 335 Towards an implantable replenishable delivery device for natural killer cell and Tri-specific killer engager antibodies to the intraperitoneal space to treat ovarian cancer
335 Towards an implantable replenishable delivery device for natural killer cell and Tri-specific killer engager antibodies to the intraperitoneal space to treat ovarian cancer Open
Background Ovarian cancer (OC) global 5-year survival rate is <30% for advanced-stage disease. Natural killer (NK) cell immunotherapy and Tri-specific Killer Engager (TriKE) antibodies have shown promising pre-clinical results. As OC is pr…