Lesley Voss
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View article: Trends in Community Antibiotic Dispensing for Children and Young People in Aotearoa New Zealand, 2010–2019: Implications for Antimicrobial Stewardship
Trends in Community Antibiotic Dispensing for Children and Young People in Aotearoa New Zealand, 2010–2019: Implications for Antimicrobial Stewardship Open
Aim To analyse trends in community systemic antibiotic dispensing to children and young people (0–14 years) in New Zealand between 2010 and 2019. Methods Dispensing data were retrieved from the National Pharmaceuticals Collection and popul…
View article: Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic data, and key evidence gaps
Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic data, and key evidence gaps Open
Summary: Gram-negative bacterial infections remain a major cause of morbidity and mortality in children and neonates globally, compounded by the rise of antimicrobial resistance. Barriers to paediatric antibiotic licencing lead to reduced …
View article: Does Adjunctive Clindamycin Have a Role in <i>Staphylococcus aureus</i> Bacteremia? A Protocol for the Adjunctive Treatment Domain of the <i>Staphylococcus aureus</i> Network Adaptive Platform (SNAP) Randomized Controlled Trial
Does Adjunctive Clindamycin Have a Role in <i>Staphylococcus aureus</i> Bacteremia? A Protocol for the Adjunctive Treatment Domain of the <i>Staphylococcus aureus</i> Network Adaptive Platform (SNAP) Randomized Controlled Trial Open
Background The use of adjunctive antibiotics directed against exotoxin production in Staphylococcus aureus bacteremia (SAB) is widespread, and it is recommended in many guidelines, but this is based on limited evidence. Existing guidelines…
View article: Early Oral Antibiotic Switch in <i>Staphylococcus aureus</i> Bacteraemia: The <i>Staphylococcus aureus</i> Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol
Early Oral Antibiotic Switch in <i>Staphylococcus aureus</i> Bacteraemia: The <i>Staphylococcus aureus</i> Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol Open
Background Staphylococcus aureus bloodstream infection (bacteremia) is traditionally treated with at least 2 weeks of intravenous (IV) antibiotics in adults, 3–7 days in children, and often longer for those with complicated disease. The cu…
View article: Group A <i>Streptococcus</i> Primary Peritonitis in Children, New Zealand
Group A <i>Streptococcus</i> Primary Peritonitis in Children, New Zealand Open
Group A Streptococcus (GAS) primary peritonitis is a rare cause of pediatric acute abdomen (sudden onset of severe abdominal pain); only 26 pediatric cases have been reported in the English language literature since 1980. We discuss 20 add…
View article: Multisystem Inflammatory Syndrome in New Zealand Children
Multisystem Inflammatory Syndrome in New Zealand Children Open
New Zealand (NZ) initially adopted an elimination approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pre-Omicron variant, the NZ pediatric population was immunologically naïve to SARS-CoV-2. This study, utilizing nat…
View article: Surveillance of pediatric parapneumonic effusion/empyema in New Zealand
Surveillance of pediatric parapneumonic effusion/empyema in New Zealand Open
Aim The incidence of childhood empyema has been increasing in some developed countries despite the introduction of pneumococcal vaccination. This study aimed to document the incidence, bacterial pathogens, and morbidity/mortality of parapn…
View article: Which Personal Protective Equipment Should I Use while Caring for Children Attending the ED? Paediatric Emergency Procedures in the COVID-19 Era and Beyond
Which Personal Protective Equipment Should I Use while Caring for Children Attending the ED? Paediatric Emergency Procedures in the COVID-19 Era and Beyond Open
ObjectivesTo determine recommendations for the use of personal protective equipment (PPE) based on transmission risk for paediatric procedures in the Emergency Department during the COVID-19 pandemic. MethodsTwo survey rounds were conducte…
View article: Pediatric <i>Staphylococcus aureus</i> Bacteremia: Clinical Spectrum and Predictors of Poor Outcome
Pediatric <i>Staphylococcus aureus</i> Bacteremia: Clinical Spectrum and Predictors of Poor Outcome Open
Background Staphylococcus aureus is a common cause of bacteremia, yet the epidemiology and predictors of poor outcome remain inadequately defined in childhood. Methods ISAIAH (Invasive Staphylococcus aureus Infections and Hospitalizations …
View article: 1138. Script for Pediatrics: Creating a Smartphone Application to Improve Antimicrobial Prescribing
1138. Script for Pediatrics: Creating a Smartphone Application to Improve Antimicrobial Prescribing Open
Background When considering antimicrobial stewardship (AMS) interventions, pediatrics is an important and often overlooked group. By 5 years of age, 97% of New Zealand (NZ) children have received antibiotics (median 8 antibiotic courses/ch…
View article: 2328. Community-Onset Invasive Bacterial Infections in Infants Under 3 Months–10 Years of Experience in Auckland, New Zealand
2328. Community-Onset Invasive Bacterial Infections in Infants Under 3 Months–10 Years of Experience in Auckland, New Zealand Open
BACKGROUND: Serious infections remain the leading cause of death in the first year of life. Sepsis in neonatal intensive care units is well described but infants with bacterial infections presenting from the community has not previously be…
View article: Public health action following an outbreak of toxigenic cutaneous diphtheria in an Auckland refugee resettlement centre
Public health action following an outbreak of toxigenic cutaneous diphtheria in an Auckland refugee resettlement centre Open
Global forced displacement has climbed to unprecedented levels due largely to regional conflict. Degraded public health services leave displaced people vulnerable to multiple environmental and infectious hazards including vaccine preventab…
View article: Antibiotic prophylaxis and neonatal surgical site infection
Antibiotic prophylaxis and neonatal surgical site infection Open
Surgical site infection (SSI) is associated with significant morbidity.1 Although neonates are particularly vulnerable to infection, there are limited data on perioperative antibiotic prophylaxis in the neonatal period and recent guideline…
View article: Summary of position statement on refugee and asylum‐seeker health
Summary of position statement on refugee and asylum‐seeker health Open
Refugee and asylum-seeker children have particular physical and mental health needs as a result of their forced migration experience, and they face barriers to comprehensive health care. The RACP supports a comprehensive health assessment …