Explanipedia

Incidence and Outcomes of Brain Metastasis in Pleural Mesothelioma in the Era of Immunotherapy Open

Margaret Stalker, Suzanne Walker, Emily S. Lebow, Emily Ling-Lin Pai, Alan G. Watts , et al. · 2025

In this retrospective study, clinically significant BM was most prevalent in those exposed to IO and not seen in those receiving chemotherapy despite similar mOS between the groups. Brain imaging should be considered before starting IO in …

Guidelines for Pathologic Diagnosis of Mesothelioma: 2023 Update of the Consensus Statement From the International Mesothelioma Interest Group Open

Aliya N. Husain, David B. Chapel, Richard Attanoos, Mary Beth Beasley, Luka Brčić , et al. · 2024

Context.— Mesothelioma is an uncommon tumor that can be difficult to diagnose. Objective.— To provide updated, practical guidelines for the pathologic diagnosis of mesothelioma. Data Sources.— Pathologists involved in the International Mes…

Transcriptional profiles of pulmonary artery endothelial cells in pulmonary hypertension Open

Navneet Singh, Carsten Eickhoff, Augusto García-Agúndez, Paul Bertone, Sunita S. Paudel , et al. · 2023

Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes…

Serotonin reduction in post-acute sequelae of viral infection Open

Andrea C. Wong, Ashwarya S. Devason, Iboro C. Umana, Timothy Cox, Lenka Dohnalová , et al. · 2023

Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells Open

Andrew R. Haas, Ryan Golden, Leslie A. Litzky, Boris Engels, Linlin Zhao , et al. · 2023

Supplementary Table 1 from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Summary of tumor mutation and T cell function

Data from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Cancer progression is marked by dysfunctional tumor-infiltrating lymphocytes (TIL) with high inhibitory receptor (IR) expression. Because IR blockade has led to clinical responses in some patients with non–small cell lung cancer (NSCLC), w…

Supplementary Table 1 from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Summary of tumor mutation and T cell function

Supplementary Figures from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Supplementary Figures 1-7

Data from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Cancer progression is marked by dysfunctional tumor-infiltrating lymphocytes (TIL) with high inhibitory receptor (IR) expression. Because IR blockade has led to clinical responses in some patients with non–small cell lung cancer (NSCLC), w…

Supplementary Methods from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Description of Flow Cytometric Methods, and killing assays.

Supplementary Figures from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Supplementary Figures 1-7

Supplementary Methods from Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer Open

Shaun O’Brien, Astero Klampatsa, Jeffrey C. Thompson, Marina C. Martinez, Wei–Ting Hwang , et al. · 2023

Description of Flow Cytometric Methods, and killing assays.

Supplementary Methods from Pilot and Feasibility Trial Evaluating Immuno-Gene Therapy of Malignant Mesothelioma Using Intrapleural Delivery of Adenovirus-IFNα Combined with Chemotherapy Open