Explanipedia

Radiation De-Escalation in Older Women with Early-Stage ER+/HER2– Invasive Breast Cancer Open

Drew Neish, Astrid Botty van den Bruele, Akiko Chiba, Lesly A. Dossett, E. Shelley Hwang · 2025

Background National recommendations since 2004 have allowed for omission of post-lumpectomy radiotherapy for patients ≥70 years old with early-stage estrogen receptor positive (ER+)/human epidermal growth factor receptor 2-negative (HER2–)…

Characterizing Surveillance Recommendations From National Comprehensive Cancer Network Guidelines Open

Alison S. Baskin, Alina Keshwani, Manvir Bains, Christina Fleischer, Lesly A. Dossett · 2025

This quality improvement study examines National Comprehensive Cancer Network clinical guidelines for cancer surveillance by type and characterizes specificity and length of recommended treatments.

Evaluating Variation in Lymph Node Sampling During Sentinel Lymph Node Biopsy for Melanoma Open

Crystal D. Taylor, Vanessa Niba, Alison S. Baskin, Nicole M. Mott, Erin Kim , et al. · 2025

Background The operative standard for melanoma, implemented by the Commission on Cancer (CoC), addresses margin width and excision depth, but does not collect information on sentinel lymph node biopsy (SLNB). However, SLNB, an implemented …

Perspectives on Commission on Cancer Standard 5.8 on Lung Cancer: A Qualitative Study Open

Alison S. Baskin, Michael D. Stover, Manvir Bains, Kelsey B. Montgomery, Wendelyn M. Oslock , et al. · 2025

Mixed opinions regarding Standard 5.8 align with currently low national compliance rates. Participants emphasized the need for additional evidence to support the standard, underscoring the importance of future prospective studies. Support …

National Variation in Implementation of Sentinel Lymph Node Biopsy for Clinically Node-Positive Patients Undergoing Neoadjuvant Therapy Open

Crystal D. Taylor, Ton Wang, Brandy Sinco, Melissa Pilewskie, Tasha M. Hughes , et al. · 2025

American College of Surgeons Operative Standards and Breast Cancer Outcomes Open

Crystal D. Taylor, Ton Wang, Alison S. Baskin, Brandy Sinco, Tasha M. Hughes , et al. · 2024

Importance The American College of Surgeons (ACS) operative standards were established to detail critical elements of cancer surgery, reduce technical variation, and improve outcomes. Two of the 6 operative standards target adequate axilla…

Redefining Cancer Screening Coverage—Screening to Diagnosis Open

Crystal D. Taylor, A. Mark Fendrick, Lesly A. Dossett · 2024

This Viewpoint discusses financial barriers for additional diagnostic steps after patients receive abnormal cancer screening test results.

Operative Standards for Cancer Surgery: Will Synoptic Reporting Really Improve Cancer Outcomes? Open

Ton Wang, H. Gilbert Welch, Lesly A. Dossett · 2024

INTRODUCTION For most early-stage solid tumors, high-quality surgery represents the greatest potential for cure. While considerable attention has been given to the quality of diagnostic staging and adjuvant therapy, relatively little atten…

Unpacking overuse of androgen deprivation therapy for prostate cancer to inform de-implementation strategies Open

Ted A. Skolarus, Sarah T. Hawley, Jane Forman, Anne Sales, Jordan B. Sparks , et al. · 2024

Background Many men with prostate cancer will be exposed to androgen deprivation therapy (ADT). While evidence-based ADT use is common, ADT is also used in cases with no or limited evidence resulting in more harm than benefit, i.e., overus…

Behavioral Interventions on Surgeons’ Preoperative Decision-Making: A Scoping Review and Critical Analysis Open

Alexis G. Antunez, Katherine Rowe, Paul Bain, Gerard M. Doherty, Lesly A. Dossett · 2023

Targets for De-implementation of Unnecessary Testing Before Low-Risk Surgery: A Qualitative Study Open

Caroline E. Richburg, Cecilia M. Pesavento, Andrew Vastardis, Alexis G. Antunez, Valerie Gavrila , et al. · 2023

Surgical Care for Racial and Ethnic Minorities and Interventions to Address Inequities Open

Sidra Bonner, Chloé Powell, J. Stewart, Lesly A. Dossett · 2023

Objective: Racial and ethnic inequities in surgical care in the United States are well documented. Less is understood about evidence-based interventions that improve surgical care and reduce or eliminate inequities. In this review, we disc…

Correction: Learning from the “tail end” of de-implementation: the case of chemical castration for localized prostate cancer Open

Ted A. Skolarus, Jane Forman, Jordan B. Sparks, Tabitha Metreger, Sarah T. Hawley , et al. · 2023

Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists Open

Carl Sars, Helena Sackey, Jan Frisell, Paul W. Dickman, Fredrik Karlsson , et al. · 2023

Purpose Phyllodes tumors of the breast are rare fibroepithelial lesions that are classified as benign, borderline or malignant. There is little consensus on best practice for the work-up, management, and follow-up of patients with phyllode…

ASO Visual Abstract: Surgeon Perspectives on Determinants of Same-Day Mastectomy: A Roadmap for Implementing Change Open

Brandon L. Ellsworth, Daniel J. Settecerri, Nicole M. Mott, Andrew Vastardis, Ahmad Hider , et al. · 2023

Surgeon Perspectives on Determinants of Same-Day Mastectomy: A Roadmap for Implementing Change Open

Brandon L. Ellsworth, Daniel J. Settecerri, Nicole M. Mott, Andrew Vastardis, Ahmad Hider , et al. · 2022

Prophylactic mastectomy and occult malignancy: Surgical and imaging considerations Open

Jessica Thompson, Brandy Sinco, Rachel L. McCaffrey, Alfred E. Chang, Michael S. Sabel , et al. · 2022

Background Sentinel node biopsy (SLNB) is not routinely recommended for patients undergoing prophylactic mastectomy (PM), yet omission remains a subject of debate among surgeons. A modern patient cohort was examined to determine occult mal…

Outcomes with adjuvant anti-PD-1 therapy in patients with sentinel lymph node-positive melanoma without completion lymph node dissection Open

Zeynep Eroglu, Kristy K. Broman, John F. Thompson, Amanda A. G. Nijhuis, Tina J. Hieken , et al. · 2022

Until recently, most patients with sentinel lymph node-positive (SLN+) melanoma underwent a completion lymph node dissection (CLND), as mandated in published trials of adjuvant systemic therapies. Following multicenter selective lymphadene…

Editorial Board Open

Herbert Chen, Paula Ferrada, Gregory D. Kennedy, A Brenessa, M Lindeman , et al. · 2022

204 Identifying Barriers to and Strategies for Implementing Same-Day Discharge after Mastectomy Open

Brandon L. Ellsworth, Daniel Settecerri, Ahmad Hider, Nicole M. Mott, Lesly A. Dossett , et al. · 2022

OBJECTIVES/GOALS: Same-day discharge (SDS) after mastectomy without reconstruction (MwoR) is cost-effective with equivalent complications rates when compared to patients discharged the day after surgery. Despite this, facilities SDS rates …

Opportunities and Challenges of Defining “Value” in Oncology Care Open

Nicole M. Mott, Lesly A. Dossett · 2022

Factors associated with disease‐free and abdominal recurrence‐free survival in abdominopelvic and retroperitoneal sarcomas Open

Brooke C. Bredbeck, Lia D. Delaney, Varun Kathawate, Cameron A. Harter, Jodi M. Wilkowski , et al. · 2022

Background and Objectives Retroperitoneal and abdominopelvic sarcomas are rare heterogeneous malignancies. The only therapy proven to improve disease‐free survival (DFS) is R0/R1 surgical resection. We sought to analyze whether additional …

ASO Visual Abstract: Review of Cancer-Specific Quality Measures Promoting the Avoidance of Low-Value Care Open

Brandon L. Ellsworth, Allan K. Metz, Nicole M. Mott, Ruby J. Kazemi, Michael D. Stover , et al. · 2022

De-escalation in breast cancer surgery Open

Sarah P. Shubeck, Monica Morrow, Lesly A. Dossett · 2022

Peace of Mind: A Role in Unnecessary Care? Open

Michelle Chen, Tasha M. Hughes, Lesly A. Dossett, Susan C. Pitt · 2021

Consider this excerpt from a real patient-surgeon conversation about treatment for a small, early-stage thyroid cancer and deliberating three equivalent treatment options: active surveillance, hemithyroidectomy, and total thyroidectomy.

Intersystem Medical Error Discovery: A Document Analysis of Ethical Guidelines. Open

Blake Duffy, Jacquelyn Miller, C. Ann Vitous, Lesly A. Dossett · 2021

Ethics codes provide little guidance on communication regarding IMED scenarios, and in some cases, the guidance is internally conflicting. National professional and patient safety organizations should work to provide a framework for provid…

Using Tailored Messages to Target Overuse of Low-Value Breast Cancer Care in Older Women Open

Lesly A. Dossett, Nicole M. Mott, Brooke C. Bredbeck, Ton Wang, Chad Jobin , et al. · 2021

Clinician Attitudes and Beliefs About Deintensifying Head and Neck Cancer Surveillance Open

Michelle Chen, Nicole M. Mott, Jacquelyn Miller, Ruby J. Kazemi, Michael D. Stover , et al. · 2021

In this qualitative study, clinicians revealed a willingness to consider altering cancer surveillance but expressed a need to maintain patient and clinician peace of mind, maintain the patient-clinician relationship, and ensure adequate mo…

Learning from the “tail end” of de-implementation: the case of chemical castration for localized prostate cancer Open

Ted A. Skolarus, Jane Forman, Jordan B. Sparks, Tabitha Metreger, Sarah T. Hawley , et al. · 2021

ASO Author Reflections: Adding up the Costs of Low-Value Breast Cancer Care Open

Brooke C. Bredbeck, Lesly A. Dossett · 2021

Lesly A. Dossett YOU? Author Swipe