Lev A. Matveev
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View article: Geophysics-Inspired Nonlinear Stress–Strain Law for Biological Tissues and Its Applications in Compression Optical Coherence Elastography
Geophysics-Inspired Nonlinear Stress–Strain Law for Biological Tissues and Its Applications in Compression Optical Coherence Elastography Open
We propose a nonlinear stress–strain law to describe nonlinear elastic properties of biological tissues using an analogy with the derivation of nonlinear constitutive laws for cracked rocks. The derivation of such a constitutive equation h…
View article: Computationally efficient adaptive optimization of vector-method parameters for phase-sensitive strain estimation in optical coherence elastography
Computationally efficient adaptive optimization of vector-method parameters for phase-sensitive strain estimation in optical coherence elastography Open
A new method for automatic adaptive optimization of strain estimation in phase-sensitive optical coherence tomography (OCT) is introduced. More specifically, this paper focuses on optimizing the estimation of strain using the vector method…
View article: K-Space Approach in Optical Coherence Tomography: Rigorous Digital Transformation of Arbitrary-Shape Beams, Aberration Elimination and Super-Refocusing beyond Conventional Phase Correction Procedures
K-Space Approach in Optical Coherence Tomography: Rigorous Digital Transformation of Arbitrary-Shape Beams, Aberration Elimination and Super-Refocusing beyond Conventional Phase Correction Procedures Open
For the most popular method of scan formation in Optical Coherence Tomography (OCT) based on plane-parallel scanning of the illuminating beam, we present a compact but rigorous K-space description in which the spectral representation is us…
View article: Features of blood supply of urethral tissues in women with primary urethral pain syndrome
Features of blood supply of urethral tissues in women with primary urethral pain syndrome Open
Introduction. Primary urethral pain syndrome (PUPS) is a part of chronic primary pelvic pain syndrome with predominant localisation of pain in the urethra. The pathogenesis of PUPS has not been adequately studied and there are no unified g…
View article: Multimodal OCT Control for Early Histological Signs of Vulvar Lichen Sclerosus Recurrence after Systemic PDT: Pilot Study
Multimodal OCT Control for Early Histological Signs of Vulvar Lichen Sclerosus Recurrence after Systemic PDT: Pilot Study Open
Photodynamic therapy (PDT) is a modern treatment for severe or treatment-resistant vulvar lichen sclerosus (VLS). The chronic and recurrent nature of VLS requires control of recurrences at an early stage. In this paper, a non-invasive mult…
View article: Side-by-Side OCE-Study of Elasticity and SHG-Characterization of Collagen Fibers in Breast Cancer Tissue before and after Chemotherapy
Side-by-Side OCE-Study of Elasticity and SHG-Characterization of Collagen Fibers in Breast Cancer Tissue before and after Chemotherapy Open
In the recent years promising results have been shown by the use of Compression optical coherence elastography (C-OCE) as a new optical biopsy approach to morphological assessment/diagnostics of human breast cancer using differences in ela…
View article: Compression OCT-elastography combined with speckle-contrast analysis as an approach to the morphological assessment of breast cancer tissue
Compression OCT-elastography combined with speckle-contrast analysis as an approach to the morphological assessment of breast cancer tissue Open
Currently, optical biopsy technologies are being developed for rapid and label-free visualization of biological tissue with micrometer-level resolution. They can play an important role in breast-conserving surgery guidance, detection of re…
View article: Numerical Study of Supra-Wavelength Axial Motion Compensation in Contact-Mode Optical Coherence Angiography Using Fourier-Shift Procedures
Numerical Study of Supra-Wavelength Axial Motion Compensation in Contact-Mode Optical Coherence Angiography Using Fourier-Shift Procedures Open
Label-free angiographic methods based on optical coherence tomography (OCT) visualize blood vessels utilizing detection of red blood cells motion against surrounding static tissue. However, in practice, the surrounding tissue is never stil…
View article: Mapping Large Strains in Phase-Sensitive OCT: Key Role of Supra-Pixel Displacement Tracking in Incremental Strain Evaluation
Mapping Large Strains in Phase-Sensitive OCT: Key Role of Supra-Pixel Displacement Tracking in Incremental Strain Evaluation Open
Displacement tracking is an important step in realization of compression optical coherence elastography (C-OCE), especially in the context of obtaining nonlinear stress-strain dependences and subsequent evaluation of the tissue Young's mod…
View article: Novel Elastography-Inspired Approach to Angiographic Visualization in Optical Coherence Tomography
Novel Elastography-Inspired Approach to Angiographic Visualization in Optical Coherence Tomography Open
In this paper, we present a new approach to contrast-agent-free angiographic visualization in optical coherence tomography (OCT). The proposed approach has much in common with imaging of local interframe strains in OCT-based elastography a…
View article: Nonlinear Elasticity Assessment with Optical Coherence Elastography for High-Selectivity Differentiation of Breast Cancer Tissues
Nonlinear Elasticity Assessment with Optical Coherence Elastography for High-Selectivity Differentiation of Breast Cancer Tissues Open
Soft biological tissues, breast cancer tissues in particular, often manifest pronounced nonlinear elasticity, i.e., strong dependence of their Young’s modulus on the applied stress. We showed that compression optical coherence elastography…
View article: Optical Coherence Tomography Angiography and Attenuation Imaging for Label-Free Observation of Functional Changes in the Intestine after Sympathectomy: A Pilot Study
Optical Coherence Tomography Angiography and Attenuation Imaging for Label-Free Observation of Functional Changes in the Intestine after Sympathectomy: A Pilot Study Open
We present in this study optical coherence tomography angiography (OCTA) and OCT attenuation imaging (OCTAI) for in vivo non-destructive visualization of intramural blood and lymphatic vessels of the intestine wall. Rabbit small intestine …
View article: Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study
Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study Open
The aims of this study are (i) to compare ultrasound strain elastography (US-SE) and compression optical coherence elastography (C-OCE) in characterization of elastically linear phantoms, (ii) to evaluate factors that can cause discrepancy…
View article: Optical Coherence Elastography as a Tool for Studying Deformations in Biomaterials: Spatially-Resolved Osmotic Strain Dynamics in Cartilaginous Samples
Optical Coherence Elastography as a Tool for Studying Deformations in Biomaterials: Spatially-Resolved Osmotic Strain Dynamics in Cartilaginous Samples Open
This paper presents a recently developed variant of phase-resolved Optical Coherence Elastography (OCE) enabling non-contact visualization of transient local strains of various origins in biological tissues and other materials. In this wor…
View article: Real-Time Strain and Elasticity Imaging in Phase-Sensitive Optical Coherence Elastography Using a Computationally Efficient Realization of the Vector Method
Real-Time Strain and Elasticity Imaging in Phase-Sensitive Optical Coherence Elastography Using a Computationally Efficient Realization of the Vector Method Open
We present a real-time realization of OCT-based elastographic mapping local strains and distribution of the Young’s modulus in biological tissues, which is in high demand for biomedical usage. The described variant exploits the principle o…
View article: Flexible Computationally Efficient Platform for Simulating Scan Formation in Optical Coherence Tomography with Accounting for Arbitrary Motions of Scatterers
Flexible Computationally Efficient Platform for Simulating Scan Formation in Optical Coherence Tomography with Accounting for Arbitrary Motions of Scatterers Open
A computationally efficient and fairly realistic model of OCT-scan formation in spectral-domain optical coherence tomography is described. The model is based on the approximation of discrete scatterers and ballistic character of scattering…
View article: Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study
Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study Open
The possibility to assess molecular-biological and morphological features of particular breast cancer types can improve the precision of resection margin detection and enable accurate determining of the tumor aggressiveness, which is impor…
View article: Quantitative Mapping of Strains and Young Modulus Based on Phase-Sensitive OCT
Quantitative Mapping of Strains and Young Modulus Based on Phase-Sensitive OCT Open
In this chapter we consider mapping of local strains and tissue elasticity in optical coherence tomography (OCT) based on analysis of phase-sensitive OCT scans. Conventional structural OCT scans correspond to spatially resolved mapping of …
View article: Computationally efficient model of OCT scan formation by focused beams and its usage to demonstrate a novel principle of OCTangiography
Computationally efficient model of OCT scan formation by focused beams and its usage to demonstrate a novel principle of OCTangiography Open
A computationally highly efficient full-wave model of OCT-scan formation by focused beams in spectral-domain optical coherence tomography (OCT) is presented. Similarly to some previous models, it is based on summation of fields scattered b…
View article: In vivo assessment of functional and morphological alterations in tumors under treatment using OCT-angiography combined with OCT-elastography
In vivo assessment of functional and morphological alterations in tumors under treatment using OCT-angiography combined with OCT-elastography Open
Emerging methods of anti-tumor therapies require new approaches to tumor response evaluation, especially enabling label-free diagnostics and in vivo utilization. Here, to assess the tumor early reaction and predict its long-term response, …
View article: Method for<i>in vivo</i>assessment of cancer tissue inhomogeneity and accurate histology-like morphological segmentation based on Optical Coherence Elastography
Method for<i>in vivo</i>assessment of cancer tissue inhomogeneity and accurate histology-like morphological segmentation based on Optical Coherence Elastography Open
We present a non-invasive method based on Optical Coherence Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents, in particular, monitoring of morphological alterations during both tumor development and…
View article: Multimodal Optical Coherence Tomography: Imaging of Blood and Lymphatic Vessels of the Vulva
Multimodal Optical Coherence Tomography: Imaging of Blood and Lymphatic Vessels of the Vulva Open
The aim of the study was to test the method of optical coherence tomography (OCT) for its ability to obtain images of blood and lymphatic vessels of the vulva.Materials and Methods.The study was performed using a multimodal optical coheren…
View article: Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography
Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography Open
Analysis of semi-transparent low scattering biological structures in optical coherence tomography (OCT) has been actively pursued in the context of lymphatic imaging, with most approaches relying on the relative absence of signal as a mean…
View article: Stabilization of the Scanning Pattern for Three-Dimensional Phase-Sensitive OCT Modalities: Angiography, Relaxography, and Monitoring of Slow Processes
Stabilization of the Scanning Pattern for Three-Dimensional Phase-Sensitive OCT Modalities: Angiography, Relaxography, and Monitoring of Slow Processes Open
New modalities of optical coherence tomography (OCT) are based not only on the analysis of light beam scattering by biological tissues, but also, to a greater extent, on the assessment of spatio-temporal changes in the speckle structure (b…