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View article: Role and mechanism of Roux-en-Y gastric bypass in the treatment of diabetic urinary bladder hyperactivity by reducing TRPV1 and P2X3
Role and mechanism of Roux-en-Y gastric bypass in the treatment of diabetic urinary bladder hyperactivity by reducing TRPV1 and P2X3 Open
Guangyong Li, Shuai Ren, Bin-Cheng Huang, Jia-Jin Feng, Qiangqiang Wang , et al. · 2025
BACKGROUND Diabetes mellitus (DM) is linked to an earlier onset and heightened severity of urinary complications, particularly bladder dysfunction, which profoundly impacts patient quality of life. Overactive bladder (OAB) is a common stor…
View article: Enhancement of protein production in Aspergillus niger by engineering the antioxidant defense metabolism
Enhancement of protein production in Aspergillus niger by engineering the antioxidant defense metabolism Open
Xin Chen, Baoxiang Pan, Le-Yi Yu, Bin Wang, Li Pan · 2024
View article: Exploration of the Strategy for Improving the Expression of Heterologous Sweet Protein Monellin in Aspergillus niger
Exploration of the Strategy for Improving the Expression of Heterologous Sweet Protein Monellin in Aspergillus niger Open
Ke Li, Junwei Zheng, Le-Yi Yu, Bin Wang, Li Pan · 2023
Aspergillus niger is a primary cell factory for food-grade protein (enzyme) production due to its strong protein secretion capacity and unique safety characteristics. The bottleneck issue for the current A. niger expression system is the d…
View article: Invasive micropapillary breast carcinoma: A retrospective study on the clinical imaging features and pathologic findings
Invasive micropapillary breast carcinoma: A retrospective study on the clinical imaging features and pathologic findings Open
Jiarui Nangong, Zhongquan Cheng, Le-Yi Yu, Xiaodan Zheng, Guoqian Ding · 2022
Purpose To describe the clinical imaging and pathological features of invasive micropapillary breast carcinoma (IMPC), including breast mammography, sonography, magnetic resonance imaging (MRI), and molecular imaging findings. Patients and…
View article: A Special Phenotype of Aconidial Aspergillus niger SH2 and Its Mechanism of Formation via CRISPRi
A Special Phenotype of Aconidial Aspergillus niger SH2 and Its Mechanism of Formation via CRISPRi Open
Le-Yi Yu, Lin-Xiang Li, Linlin Yao, Junwei Zheng, Bin Wang , et al. · 2022
The complex morphological structure of Aspergillus niger influences its production of proteins, metabolites, etc., making the genetic manipulation and clonal purification of this species increasingly difficult, especially in aconidial Aspe…
View article: Impact of overexpressing NADH kinase on glucoamylase production in <i>Aspergillus niger</i>
Impact of overexpressing NADH kinase on glucoamylase production in <i>Aspergillus niger</i> Open
Lin-Xiang Li, Le-Yi Yu, Bin Wang, Li Pan · 2022
Glucoamylase has a wide range of applications in the production of glucose, antibiotics, amino acids, and other fermentation industries. Fungal glucoamylase, in particular, has attracted much attention because of its wide application in di…
View article: Screening of probiotics with efficient α-glucosidase inhibitory ability and study on the structure and function of its extracellular polysaccharide
Screening of probiotics with efficient α-glucosidase inhibitory ability and study on the structure and function of its extracellular polysaccharide Open
Jiabin Wang, Le-Yi Yu, Xu Zeng, Junwei Zheng, Bin Wang , et al. · 2021
View article: A Study on Prevalence and Characterization of Bacillus cereus in Ready-to-Eat Foods in China
A Study on Prevalence and Characterization of Bacillus cereus in Ready-to-Eat Foods in China Open
Shubo Yu, Pengfei Yu, Juan Wang, Chun Li, Hui Guo , et al. · 2020
Bacillus cereus is widely distributed in different food products and can cause a variety of symptoms associated with food poisoning. Since ready-to-eat (RTE) foods are not commonly sterilized by heat treatment before consumption,




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