Leyun Pan
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View article: Non-[18F]FDG PET-Radiopharmaceuticals in Oncology
Non-[18F]FDG PET-Radiopharmaceuticals in Oncology Open
Molecular imaging is a growing field, driven by technological advances, such as the improvement of PET-CT scanners through the introduction of digital detectors and scanners with an extended field of view, resulting in much higher sensitiv…
View article: Total Body PET-CT Protocols in Oncology
Total Body PET-CT Protocols in Oncology Open
Recently developed long axial field of view (LAFOV) PET-CT scanners, including total body scanners, are already in use in a few centers worldwide. These systems have some major advantages over standard axial field of view (SAFOV) PET-CT sc…
View article: Artificial intelligence–based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma
Artificial intelligence–based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma Open
Purpose Multiple myeloma (MM) is a highly heterogeneous disease with wide variations in patient outcome. [ 18 F]FDG PET/CT can provide prognostic information in MM, but it is hampered by issues regarding standardization of scan interpretat…
View article: Long axial field of view (LAFOV) PET-CT: implementation in static and dynamic oncological studies
Long axial field of view (LAFOV) PET-CT: implementation in static and dynamic oncological studies Open
Long axial field of view (LAFOV) PET-CT scanners have been recently developed and are already in clinical use in few centers worldwide. Although still limited, the hitherto acquired experience with these novel systems highlights an increas…
View article: Fractal and Multifractal Analysis of PET-CT Images for Therapy Assessment of Metastatic Melanoma Patients under PD-1 Inhibitors: A Feasibility Study
Fractal and Multifractal Analysis of PET-CT Images for Therapy Assessment of Metastatic Melanoma Patients under PD-1 Inhibitors: A Feasibility Study Open
Longitudinal whole-body PET-CT scans with F-18-fluorodeoxyglucose (18F-FDG) in patients suffering from metastatic melanoma were analyzed and the tracer distribution in patients was compared with that of healthy controls. Nineteen patients …
View article: Interim [18F]FDG PET/CT can predict response to anti-PD-1 treatment in metastatic melanoma
Interim [18F]FDG PET/CT can predict response to anti-PD-1 treatment in metastatic melanoma Open
Purpose In an attempt to identify biomarkers that can reliably predict long-term outcomes to immunotherapy in metastatic melanoma, we investigated the prognostic role of [ 18 F]FDG PET/CT, performed at baseline and early during the course …
View article: Multi-Path Dilated Residual Network for Nuclei Segmentation and Detection
Multi-Path Dilated Residual Network for Nuclei Segmentation and Detection Open
As a typical biomedical detection task, nuclei detection has been widely used in human health management, disease diagnosis and other fields. However, the task of cell detection in microscopic images is still challenging because the nuclei…
View article: Discussion on operative skills in the embolization of hydrosalpinx by hysteroscopic placement of a microcoil
Discussion on operative skills in the embolization of hydrosalpinx by hysteroscopic placement of a microcoil Open
This study aims to discuss the operative skills of hysteroscopic tubal embolization and reduce the occurrence of complications. Ninety-four patients were divided into group A and group B. The main surgical technique in group A: when the in…
View article: Automatic Classification of CAD ECG Signals With SDAE and Bidirectional Long Short-Term Network
Automatic Classification of CAD ECG Signals With SDAE and Bidirectional Long Short-Term Network Open
Coronary artery disease (CAD) has been one of main causes of heart diseases globally. The electrocardiogram (ECG) is a widely used diagnostic tool to monitor patients' heart activities, and medical personnel need to judge whether there are…
View article: Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape
Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape Open
This work represents an effort for the integrative, multilayered, signature-oriented analysis of CRC, in the context of radio-genomics, inferring a composite signature with promising results for patient stratification.
View article: <sup>68</sup>Ga-PSMA-11 PET/CT in prostate cancer local recurrence: impact of early images and parametric analysis.
<sup>68</sup>Ga-PSMA-11 PET/CT in prostate cancer local recurrence: impact of early images and parametric analysis. Open
68Ga-PSMA-11 PET/CT performed 60 min post tracer injection (p.i.) can underestimate prostate cancer (PC) local recurrence, due to high 68Ga-PSMA-11 urinary bladder accumulation. Aim of this analysis is to evaluate the complementary role of…
View article: Correction to: Imaging therapy response of gastrointestinal stromal tumors (GIST) with FDG PET, CT and MRI: a systematic review
Correction to: Imaging therapy response of gastrointestinal stromal tumors (GIST) with FDG PET, CT and MRI: a systematic review Open
The article "Imaging therapy response of gastrointestinal stromal tumors (GIST) with FDG PET, CT and MRI: a systematic review", written by Antonia Dimitrakopoulou-Strauss, Ulrich Ronellenfitsch, Caixia Cheng, Leyun Pan, Christos Sachpekidi…
View article: Imaging therapy response of gastrointestinal stromal tumors (GIST) with FDG PET, CT and MRI: a systematic review
Imaging therapy response of gastrointestinal stromal tumors (GIST) with FDG PET, CT and MRI: a systematic review Open
Purpose Improvement of the therapeutic approaches in gastrointestinal stromal tumors (GIST) by the introduction of targeted therapies requires appropriate diagnostic tools, which allow sufficient assessment of therapeutic response, includi…
View article: Fractal and multifractal analysis of PET/CT images of metastatic melanoma before and after treatment with ipilimumab.
Fractal and multifractal analysis of PET/CT images of metastatic melanoma before and after treatment with ipilimumab. Open
PET/CT with F-18-Fluorodeoxyglucose (FDG) images of patients suffering from metastatic melanoma have been analysed using fractal and multifractal analysis to assess the impact of monoclonal antibody ipilimumab treatment with respect to the…