Ling‐Feng Wang
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View article: Low Geriatric Nutritional Risk Index Predicts Unfavorable Outcomes in Older Sudden Sensorineural Hearing Loss Patients
Low Geriatric Nutritional Risk Index Predicts Unfavorable Outcomes in Older Sudden Sensorineural Hearing Loss Patients Open
Importance Sudden sensorineural hearing loss (SSNHL) is associated with metabolic syndrome, central obesity, and albumin level. Malnutrition may adversely affect recovery in older patients with SSNHL, yet its clinical relevance remains und…
View article: The <scp>PI3K</scp> Inhibitor <scp>HCD</scp> Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways
The <span>PI3K</span> Inhibitor <span>HCD</span> Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways Open
Background 16‐hydroxycleroda‐3,13‐dien‐15,16‐olide (HCD), a compound isolated from Polyalthia longifolia var. pendula , has been identified as a PI3K inhibitor. P. longifolia var. pendula is recognized for its diverse pharmacological prope…
View article: Exploring the economic occupational health, safety, and fatal accidents in high-risk industries
Exploring the economic occupational health, safety, and fatal accidents in high-risk industries Open
View article: Efficient phosphorus removal using the La-based perovskite oxides: Role of B-site metal for modulating the surface electronic structure
Efficient phosphorus removal using the La-based perovskite oxides: Role of B-site metal for modulating the surface electronic structure Open
Highly efficient removal of phosphate from water bodies is of great importance to controlling eutrophication. Herein, the lanthanum-based perovskites (i.e., LaMnO3, LaFeO3) were synthesized and employed for phosphorus adsorption. Adsorptio…
View article: Dynamic change in silent sinus syndrome
Dynamic change in silent sinus syndrome Open
A 32-year-old male patient presented to the otolaryngology outpatient department after experiencing visible progressive facial misalignment for 3 weeks. He complained about the sunken appearance of his left eye and the asymmetric protrusio…
View article: Identification of genes related to growth and amino acid metabolism from the transcriptome profile of the liver of growing laying hens
Identification of genes related to growth and amino acid metabolism from the transcriptome profile of the liver of growing laying hens Open
The growing period is a critical period for the growth and development of hens and affects their production performance during the laying period. During the early stage of growing, bone and muscle growth is rapid, making it necessary to pr…
View article: Protective effect and possible mechanisms of geniposide for ischemia-reperfusion injury: A systematic review with meta-analysis and network pharmacology of preclinical evidence
Protective effect and possible mechanisms of geniposide for ischemia-reperfusion injury: A systematic review with meta-analysis and network pharmacology of preclinical evidence Open
View article: Study on integrated treatment of severe burn in batch patients
Study on integrated treatment of severe burn in batch patients Open
Objective: To explore the burn treatment and first aid flow mode in batch patients.Methods: A retrospective analysis was performed on the treatment experience of 10 or more patients in the group burn accident admitted to the Third Affiliat…
View article: Effects of Methyl Sulfonyl Methane and Selenium Yeast on Fatty Liver Syndrome in Laying Hens and Their Biological Mechanisms
Effects of Methyl Sulfonyl Methane and Selenium Yeast on Fatty Liver Syndrome in Laying Hens and Their Biological Mechanisms Open
The purpose of this study was to explore the effects of MSM and Se-Y on FLS in laying hens during the late peak laying period and the underlying biological mechanisms. Therefore 240 55-week-old Jing-fen No. 6 laying hens were randomly divi…
View article: Review, impact, and future of severe and extra-severe burn treatment in China
Review, impact, and future of severe and extra-severe burn treatment in China Open
China began using the colored liquid from tea and tincture to treat burns as early as the sixth century B.C., and records of Chinese medicine for the rescue and treatment of burns date from the Jin Dynasty to the Ming and Qing Dynasties. M…
View article: Glucocorticoid receptor (<i>NR3C1</i>) genetic polymorphisms and the outcomes of sudden sensorineural hearing loss
Glucocorticoid receptor (<i>NR3C1</i>) genetic polymorphisms and the outcomes of sudden sensorineural hearing loss Open
Background The glucocorticoid receptor gene ( NR3C1) encodes the receptor to which cortisol and other glucocorticoids bind. Steroids in either oral, intratympanic, or intravascular forms are the treatment of choice for sudden sensorineural…
View article: Growth Regulated Oncogene-α Upregulates TNF-α and COX-2 and Activates NOD1/RIPK2 mediated-MAPK Pathway in Head and Neck Squamous Cell Carcinoma
Growth Regulated Oncogene-α Upregulates TNF-α and COX-2 and Activates NOD1/RIPK2 mediated-MAPK Pathway in Head and Neck Squamous Cell Carcinoma Open
Purpose: The long-term prognosis and survival rate of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) are poor, although the identification of specific biomarkers that reveal its nature and aggres…
View article: Effect of <scp>KRAS</scp> mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer
Effect of <span>KRAS</span> mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer Open
Background In the occurrence and development of colorectal cancer, p53 is an important regulator downstream of the MAPK signaling pathway and plays an important role in inhibiting abnormal proliferation signals generated by KRAS mutations.…
View article: Evaluation of Stroke Risk in Patients With Atrial Fibrillation Using Morphological and Hemodynamic Characteristics
Evaluation of Stroke Risk in Patients With Atrial Fibrillation Using Morphological and Hemodynamic Characteristics Open
Background It is well known that the thrombus triggering stroke in patients with atrial fibrillation (AF) mainly comes from the left atrial appendage (LAA). This study aims to characterize the morphological and hemodynamic parameters and e…
View article: Accumulation of Experience and Newly Developed Devices Can Improve the Safety and Voice Outcome of Total Thyroidectomy for Graves’ Disease
Accumulation of Experience and Newly Developed Devices Can Improve the Safety and Voice Outcome of Total Thyroidectomy for Graves’ Disease Open
Total thyroidectomy (TT) in patients with Graves’ disease is challenging even for an experienced thyroid surgeon. This study aimed to investigate the accumulation of experience and applying newly developed devices on major complications an…
View article: Secondary primary malignancy in patients with head and neck squamous cell carcinoma: 27-year experience from the perspective of diagnostic tools
Secondary primary malignancy in patients with head and neck squamous cell carcinoma: 27-year experience from the perspective of diagnostic tools Open
Background The survival rate of head and neck squamous cell carcinoma (HNSCC) patients with secondary primary malignancy (SPM) showed no significant improvement for decades, however, the impact of advances in diagnostic tools is rarely men…
View article: A fully automatic artificial intelligence–based CT image analysis system for accurate detection, diagnosis, and quantitative severity evaluation of pulmonary tuberculosis
A fully automatic artificial intelligence–based CT image analysis system for accurate detection, diagnosis, and quantitative severity evaluation of pulmonary tuberculosis Open
View article: Improving Voice Outcomes After Thyroid Surgery – Review of Safety Parameters for Using Energy-Based Devices Near the Recurrent Laryngeal Nerve
Improving Voice Outcomes After Thyroid Surgery – Review of Safety Parameters for Using Energy-Based Devices Near the Recurrent Laryngeal Nerve Open
Technological advances in thyroid surgery have rapidly increased in recent decades. Specifically, recently developed energy-based devices (EBDs) enable simultaneous dissection and sealing tissue. EBDs have many advantages in thyroid surger…
View article: New Developments in Anterior Laryngeal Recording Technique During Neuromonitored Thyroid and Parathyroid Surgery
New Developments in Anterior Laryngeal Recording Technique During Neuromonitored Thyroid and Parathyroid Surgery Open
A recurrent laryngeal nerve (RLN) injury resulting in vocal fold paralysis and dysphonia remains a major source of morbidity after thyroid and parathyroid surgeries. Intraoperative neural monitoring (IONM) is increasingly accepted as an ad…
View article: Study on the mechanism of microporous sheep ADM combined with hUCMSC in promoting wound healing
Study on the mechanism of microporous sheep ADM combined with hUCMSC in promoting wound healing Open
Objective: To explore the therapeutic mechanism of microporous sheep acellular dermal matrix (ADM) combined with human umbilical cord mesenchymal stem cell (hUCMSC) to promote the healing of full-thickness skin defect.Methods: hUCMSC was c…
View article: WITHDRAWN: Exosomes Derived from Bone Marrow Mesenchymal Stem Cell Preconditioned by Low-Intensity Pulsed Ultrasound Stimulation Promote Bone-Tendon Interface Fibrocartilage Regeneration and Ameliorate Rotator Cuff Fatty Infiltration
WITHDRAWN: Exosomes Derived from Bone Marrow Mesenchymal Stem Cell Preconditioned by Low-Intensity Pulsed Ultrasound Stimulation Promote Bone-Tendon Interface Fibrocartilage Regeneration and Ameliorate Rotator Cuff Fatty Infiltration Open
Fibrovascular scar healing of bone-tendon interface (BTI) instead of functional fibrocartilage regeneration is the main concern associated with unsatisfactory prognosis in rotator cuff repair. Mesenchymal stem cells exosomes have been repo…
View article: Effects of platelet-rich plasma on in vitro proliferation and migration of fibroblasts from human chronic refractory wound granulation tissue
Effects of platelet-rich plasma on in vitro proliferation and migration of fibroblasts from human chronic refractory wound granulation tissue Open
Objective: To observe the effects of platelet-rich plasma (PRP) on in vitro proliferation and migration of fibroblasts from human chronic refractory wound granulation tissue.Methods: Fibroblasts were separated from human chronic refractory…
View article: A Fully Automatic AI-based CT Image Analysis System for Accurate Detection, Diagnosis, and Quantitative Severity Evaluation of Pulmonary Tuberculosis
A Fully Automatic AI-based CT Image Analysis System for Accurate Detection, Diagnosis, and Quantitative Severity Evaluation of Pulmonary Tuberculosis Open
Background: Accurate and rapid diagnosis of pulmonary tuberculosis (TB) plays a crucial role in timely prevention and appropriate medical treatment to the disease. This study aims to develop and evaluate an artificial intelligence (AI)-bas…
View article: Association of sudden sensorineural hearing loss with dementia: a nationwide cohort study
Association of sudden sensorineural hearing loss with dementia: a nationwide cohort study Open
Background Impaired cochlear blood perfusion and microvascular damage can cause sudden sensorineural hearing loss (SSHL), which is a potential risk factor for dementia. This study explored the association between SSHL and dementia. Methods…
View article: Analysis of the impact of COVID-19 on some medical institutions in a certain region
Analysis of the impact of COVID-19 on some medical institutions in a certain region Open
Objective: This study is designed to analyze the impact of COVID-19 on hospitals in a certain region through the statistical comparison of outpatient, emergency and inpatient data of three representative AAA hospitals in this region from J…
View article: The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with sudden sensorineural hearing loss in a Taiwanese population: A case control study
The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with sudden sensorineural hearing loss in a Taiwanese population: A case control study Open
Background Sudden sensorineural hearing loss (SSNHL) is a disease with an unknown etiology; damage to the auditory nerve from inflammation due to viral infection or vascular incidents has been implicated. According to several studies, cyto…
View article: Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells
Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells Open
Prolonged treatment with cisplatin (CDDP) frequently develops chemoresistance. We have previously shown that p22phox, an endoplasmic reticulum (ER) membrane protein, confers CDDP resistance by blocking CDDP nuclear entry in oral squamous c…
View article: Peculiar anatomic variation of recurrent laryngeal nerve and EMG change in a patient with right substernal goiter and pre-operative vocal cord palsy—case report
Peculiar anatomic variation of recurrent laryngeal nerve and EMG change in a patient with right substernal goiter and pre-operative vocal cord palsy—case report Open
We report a patient with right substernal goiter and preoperative vocal cord palsy (VCP). During dissection, an anatomic variation of the recurrent laryngeal nerve (RLN) and a prolonged EMG were detected by intraoperative neuromonitoring (…
View article: Proactive measures for the pandemic <scp>COVID</scp>‐19 infection in outpatient clinics of Otolaryngology Department
Proactive measures for the pandemic <span>COVID</span>‐19 infection in outpatient clinics of Otolaryngology Department Open
The coronavirus disease 2019 (COVID-19) has become a serious pandemic. According to a report from Wuhan, China, 40 (29%) health professionals were among the first 138 patients to be consecutively hospitalized.1 The reported symptoms of COV…
View article: Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage Open