Yu‐Chuan Li
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View article: Genomic Epidemiological Characteristics of Enteric Adenovirus F40 and F41 in Yantai, China, from 2022 to 2023
Genomic Epidemiological Characteristics of Enteric Adenovirus F40 and F41 in Yantai, China, from 2022 to 2023 Open
This study aims to investigate the genomic epidemiological characteristics of enteric adenovirus types F40 and F41 circulating in Yantai from August 2022 to August 2023, with a focus on genetic diversity, recombination events, and their po…
View article: Complement C3/C3a-CCL9 feedback loop orchestrates inflammatory crosstalk to accelerate aortic dissection
Complement C3/C3a-CCL9 feedback loop orchestrates inflammatory crosstalk to accelerate aortic dissection Open
Aortic dissection (AD) is a life-threatening vascular disease marked by severe inflammation and immune cell infiltration. While complement activation has been implicated, the specific roles of complement component 3 (C3) and its active fra…
View article: Epidemiological and phylogenetic characteristics of human metapneumovirus in Beijing, China, 2014–2024
Epidemiological and phylogenetic characteristics of human metapneumovirus in Beijing, China, 2014–2024 Open
In November 2024, there was an unusual surge in human metapneumovirus (hMPV) infection cases in Beijing. We performed an epidemiological investigation among cases with acute respiratory tract infection (ARTI). We enrolled ARTI cases from 3…
View article: Strategic Adjustment Tactics for Enterprises to Deal with Macroeconomic Fluctuation
Strategic Adjustment Tactics for Enterprises to Deal with Macroeconomic Fluctuation Open
Macroeconomic fluctuations pose systematic challenges to business operations, and their global conductivity, industrial restructuring and policy technology superposition significantly amplify uncertainty risks. Based on the dual perspectiv…
View article: Case Report: Observation of early-onset high myopia with fundus tessellation changes in Coffin–Siris syndrome 9 (CSS9) and literature review
Case Report: Observation of early-onset high myopia with fundus tessellation changes in Coffin–Siris syndrome 9 (CSS9) and literature review Open
Coffin-Siris syndrome 9 (CSS9), a rare congenital disorder caused by SRY-related HMG-box 11 gene ( SOX11 ) deficiency, is characterized by high phenotypic heterogeneity including a wide spectrum of organ anomalies. Pathogenic variants in S…
View article: MHSNet:An MoE-based Hierarchical Semantic Representation Network for Accurate Duplicate Resume Detection with Large Language Model
MHSNet:An MoE-based Hierarchical Semantic Representation Network for Accurate Duplicate Resume Detection with Large Language Model Open
To maintain the company's talent pool, recruiters need to continuously search for resumes from third-party websites (e.g., LinkedIn, Indeed). However, fetched resumes are often incomplete and inaccurate. To improve the quality of third-par…
View article: Changes in Knowledge and Attitudes Towards Mental Disorders in a Chinese Sample Population—A Web-based Approach
Changes in Knowledge and Attitudes Towards Mental Disorders in a Chinese Sample Population—A Web-based Approach Open
Background On October 10, 2022, The Lancet Psychiatry launched a global campaign aimed at ending the stigma surrounding mental illness, reinforcing the need for continued efforts to combat this pervasive issue. We previously surveyed knowl…
View article: Hypertension Decoded: What 367,000 Real-World Cases Tell Us About Adolescents and Young Adults
Hypertension Decoded: What 367,000 Real-World Cases Tell Us About Adolescents and Young Adults Open
While the evidence of damaging effects of hypertension is widely present in the literature, the evidence of how the time of index event influences future health burden of individuals is less prevalent. By using data from 367,809 patients i…
View article: Early Detection of Lung Cancer Using a Convolutional Neural Network Integrating Multidimensional Clinical Information
Early Detection of Lung Cancer Using a Convolutional Neural Network Integrating Multidimensional Clinical Information Open
Lung cancer remains one of the leading causes of cancer-related deaths worldwide, primarily due to late-stage detection. Early diagnosis significantly improves survival rates, yet current screening methods face limitations in cost, accessi…
View article: Brain Response and 6-Month Responsiveness Exploration in Brain Infarction Case: Preliminary Study
Brain Response and 6-Month Responsiveness Exploration in Brain Infarction Case: Preliminary Study Open
Brain response to command can be detected using task-based EEG. Insufficient evidence of brain response and prognosis remain happen in brain infarction. This preliminary study aimed to explore brain response in task-based electroencephalog…
View article: AN IOT-ENABLED MULTIMODAL FRAMEWORK FOR REAL-TIME SLEEP QUALITY ASSESSMENT AND HEALTH MONITORING
AN IOT-ENABLED MULTIMODAL FRAMEWORK FOR REAL-TIME SLEEP QUALITY ASSESSMENT AND HEALTH MONITORING Open
Reliable evaluation of sleep quality plays a vital role in maintaining overall health and detecting sleep disorders. Traditional monitoring methods often suffer from delayed analysis and risks to data privacy. To tackle these challenges, t…
View article: Verifying Pluripotency in Acorn Worms
Verifying Pluripotency in Acorn Worms Open
This study aims to verify the pluripotency of acorn worm (Enteropneusta) cells using two different experimental methods. Acorn worms are marine invertebrates whose unique characteristics make them ideal subjects for this research. The firs…
View article: ChatGPT Performance Deteriorated in Patients with Comorbidities When Providing Cardiological Therapeutic Consultations
ChatGPT Performance Deteriorated in Patients with Comorbidities When Providing Cardiological Therapeutic Consultations Open
Background: Large language models (LLMs) like ChatGPT are increasingly being explored for medical applications. However, their reliability in providing medication advice for patients with complex clinical situations, particularly those wit…
View article: Pien-Tze-Huang alleviates lithocholic acid-induced cholestasis in mice by shaping bile acid-submetabolome
Pien-Tze-Huang alleviates lithocholic acid-induced cholestasis in mice by shaping bile acid-submetabolome Open
Background Cholestasis is one of the most common and devastating manifestations of liver diseases. Although bile acid (BA) metabolism disturbances have been disclosed to be related to the etiopathogenesis of cholestasis, further research i…
View article: Molecular mechanism of bisphenols induction of breast cancer through PGR revealed by network toxicology and transcriptomics integration analysis
Molecular mechanism of bisphenols induction of breast cancer through PGR revealed by network toxicology and transcriptomics integration analysis Open
Bisphenols are widely found in plastic products and may be hazardous to human health due to their estrogenic effects. Bisphenols may be involved in the carcinogenic process through endocrine-disrupting properties, especially in breast canc…
View article: Using technology acceptance model to explore physicians’ perspectives of clinical decision support system alerts
Using technology acceptance model to explore physicians’ perspectives of clinical decision support system alerts Open
Objective To examine factors influencing physicians’ perspectives of clinical decision support system (CDSS) alerts using the Technology Acceptance Model (TAM), focusing on perceived ease of use (PEOU), perceived usefulness (PU), attitude …
View article: Nondestructive analysis of architectural decorative patterns in Prince Kung’s Palace by Raman and XRF
Nondestructive analysis of architectural decorative patterns in Prince Kung’s Palace by Raman and XRF Open
This study used portable Raman spectroscopy and X-ray fluorescence to non-destructively analyze pigments in the architectural decorative patterns of Prince Kung’s Palace, Beijing. Focusing on eight representative patterns, it identified a …
View article: Evaluation of Diagnostic Recommendations Embedded in Medication Alerts: Prospective Single-Arm Interventional Study
Evaluation of Diagnostic Recommendations Embedded in Medication Alerts: Prospective Single-Arm Interventional Study Open
Background Potentially inappropriate prescribing in outpatient care contributes to adverse outcomes and health care inefficiencies. Clinical decision support systems (CDSS) offer promising solutions, but their effectiveness is often constr…
View article: Non-negligible Unemployment and Economic Losses on Ski Industry in a Warmer Northern Hemisphere
Non-negligible Unemployment and Economic Losses on Ski Industry in a Warmer Northern Hemisphere Open
Global climate warming poses significant challenges to the ski industry in the Northern Hemisphere. Here we develop an analytical framework by integrating downscaled snow depth simulations, machine learning techniques, and multi-regional i…
View article: Validating nonverbal cues for assessing physician empathy in telemedicine: a Delphi study
Validating nonverbal cues for assessing physician empathy in telemedicine: a Delphi study Open
Nonverbal communication is essential in physician-patient interaction, especially in telemedicine where verbal cues may be limited. This study aimed to identify and validate key nonverbal cues for assessing physician empathy in telemedicin…
View article: Impact of large language model (ChatGPT) in healthcare: an umbrella review and evidence synthesis
Impact of large language model (ChatGPT) in healthcare: an umbrella review and evidence synthesis Open
Background The emergence of Artificial Intelligence (AI), particularly Chat Generative Pre-Trained Transformer (ChatGPT), a Large Language Model (LLM), in healthcare promises to reshape patient care, clinical decision-making, and medical e…
View article: GUAVA: Generalizable Upper Body 3D Gaussian Avatar
GUAVA: Generalizable Upper Body 3D Gaussian Avatar Open
Reconstructing a high-quality, animatable 3D human avatar with expressive facial and hand motions from a single image has gained significant attention due to its broad application potential. 3D human avatar reconstruction typically require…