Junlang Li
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View article: Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis
Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis Open
Idiopathic pulmonary fibrosis (IPF) remains an incurable form of interstitial lung disease with sub‐optimal treatments that merely address adverse symptoms or slow fibrotic progression. Here, inhalable hsa‐miR‐30a‐3p‐loaded liposomes (miR‐…
View article: Intrapericardial long non-coding RNA-Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair.
Intrapericardial long non-coding RNA-Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair. Open
AIMS: Epicardium and epicardium-derived cells are critical players in myocardial fibrosis. Mesenchymal stem cell-derived extracellular vesicles (EVs) have been studied for cardiac repair to improve cardiac remodelling, but the actual mecha…
View article: Establishment and Application of a Model for SARS-CoV-2 Infection of Human Nasal Mucosa Organoid
Establishment and Application of a Model for SARS-CoV-2 Infection of Human Nasal Mucosa Organoid Open
Background: The COVID-19 pandemic underscores the need for effective models to study SARS-CoV-2 infection and evaluate antiviral therapies. Objectives: This study aimed to develop a human nasal organoid model to assess susceptibility to SA…
View article: Optimizing cell therapy by sorting cells with high extracellular vesicle secretion
Optimizing cell therapy by sorting cells with high extracellular vesicle secretion Open
Critical challenges remain in clinical translation of extracellular vesicle (EV)-based therapeutics due to the absence of methods to enrich cells with high EV secretion. Current cell sorting methods are limited to surface markers that are …
View article: Molecular distinctions of bronchoalveolar and alveolar organoids under differentiation conditions
Molecular distinctions of bronchoalveolar and alveolar organoids under differentiation conditions Open
The bronchoalveolar organoid (BAO) model is increasingly acknowledged as an ex‐vivo platform that accurately emulates the structural and functional attributes of proximal airway tissue. The transition from bronchoalveolar progenitor cells …
View article: Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials Open
Supplementary material (Figs. S1-S4) is available in the online version of this article at 10.1007/s12274-023-5374-3.
View article: Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3
Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3 Open
Background: Mesenchymal stem cell (MSC)-derived exosomes are well recognized immunomodulating agents for cardiac repair, while the detailed mechanisms remain elusive. The Pericardial drainage pathway provides the heart with immunosurveilla…
View article: Dual-Channel Convolutional Neural Network for Bare Surface Soil Moisture Inversion Based on Polarimetric Scattering Models
Dual-Channel Convolutional Neural Network for Bare Surface Soil Moisture Inversion Based on Polarimetric Scattering Models Open
The polarimetric synthetic aperture radar (PolSAR) can be used to obtain soil moisture by inverting scattering models at high resolution. The convolutional neural network (CNN) has been recently introduced to estimate soil roughness for Po…
View article: Zoledronate alters natural progression of tissue‐engineered vascular grafts
Zoledronate alters natural progression of tissue‐engineered vascular grafts Open
Macrophages are a critical driver of neovessel formation in tissue‐engineered vascular grafts (TEVGs), but also contribute to graft stenosis, a leading clinical trial complication. Macrophage depletion via liposomal delivery of clodronate,…
View article: All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart
All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart Open
In the past decades, numerous preclinical studies and several clinical trials have evidenced the feasibility of cell transplantation in treating heart diseases. Over the years, different delivery routes of cell therapy have emerged and bro…
View article: Engineering better stem cell therapies for treating heart diseases
Engineering better stem cell therapies for treating heart diseases Open
For decades, stem cells and their byproducts have shown efficacy in repairing tissues and organs in numerous pre-clinical studies and some clinical trials, providing hope for possible cures for many important diseases. However, the transla…
View article: High-sensitive transmission type of gas sensor based on guided-mode resonance in coupled gratings
High-sensitive transmission type of gas sensor based on guided-mode resonance in coupled gratings Open
A new type of high-sensitive transmission gas sensor based on the coupled gratings (CGs) and the corresponding Fabry–Pérot-like (FP-like) model for evaluating the resonance peaks are presented. The estimated locations of the FP-like resona…
View article: Double-channel absorption enhancement of graphene using narrow groove metal grating
Double-channel absorption enhancement of graphene using narrow groove metal grating Open
A structure containing substrate/narrow groove metal grating/covering layer/graphene is constructed. The operational principle of the structure is based on the surface plasmon polariton (SPP) resonance excited by the metal grating and the …
View article: Enhancement transmission filter using a two-dimensional subwavelength periodic membrane
Enhancement transmission filter using a two-dimensional subwavelength periodic membrane Open
Enhancement transmission filter using a two-dimensional (2-D) subwavelength periodic membrane is proposed. It can be found that strong refractive-index modulation of the silicon periodic membrane can support the excitation of multiple guid…