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View article: Prevalence, Molecular Characterization, and Antimicrobial Resistance Profile of Enterotoxigenic Escherichia coli Isolates from Pig Farms in China
Prevalence, Molecular Characterization, and Antimicrobial Resistance Profile of Enterotoxigenic Escherichia coli Isolates from Pig Farms in China Open
Enterotoxigenic Escherichia coli (ETEC) poses a critical threat to livestock health and food safety, particularly in regard to misuse of antimicrobial agents, which have accelerated the evolution of multidrug-resistant (MDR) ETEC strains, …
View article: Low‐Level Viremia Impairs Efficacy of Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma
Low‐Level Viremia Impairs Efficacy of Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma Open
Background and Aims The impact of low‐level viremia(LLV) on the efficacy of immune checkpoint inhibitors (ICIs) in unresectable hepatocellular carcinoma(uHCC) patients remains unclear. This study aims to investigate the effect of LLV on th…
View article: Study on the Effect of Phillyrin on Streptococcus suis In Vivo and In Vitro
Study on the Effect of Phillyrin on Streptococcus suis In Vivo and In Vitro Open
As a zoonotic pathogen, S. suis serotype 2 (SS2) can cause severe diseases in both pigs and humans, and develop resistance to antibiotics. Plant natural compounds are regarded as promising alternatives to conventional antibiotics. Phillyri…
View article: Neutrophil extracellular traps with low concentrations induce proliferation and migration of human fibroblasts via activating CCDC25/ILK/PI3K/AKT pathway
Neutrophil extracellular traps with low concentrations induce proliferation and migration of human fibroblasts via activating CCDC25/ILK/PI3K/AKT pathway Open
Neutrophil plays an important role in the early stage of wound healing. Excessive neutrophil extracellular traps (NETs) which are produced by neutrophil have been proved as a significant unfavorable factor for wound healing by impairing th…
View article: Gut mycobiome alterations in obesity in geographically different regions
Gut mycobiome alterations in obesity in geographically different regions Open
The gut fungi play important roles in human health and are involved in energy metabolism. This study aimed to examine gut mycobiome composition in obese subjects in two geographically different regions in China and to identify specific gut…
View article: Recognition of outer membrane proteins using multiple feature fusion
Recognition of outer membrane proteins using multiple feature fusion Open
Introduction: Outer membrane proteins are crucial in maintaining the structural stability and permeability of the outer membrane. Outer membrane proteins exhibit several functions such as antigenicity and strong immunogenicity, which have …
View article: Computational identification of promoters in Klebsiella aerogenes by using support vector machine
Computational identification of promoters in Klebsiella aerogenes by using support vector machine Open
Promoters are the basic functional cis-elements to which RNA polymerase binds to initiate the process of gene transcription. Comprehensive understanding gene expression and regulation depends on the precise identification of promoters, as …
View article: Prediction of apoptosis protein subcellular location based on amphiphilic pseudo amino acid composition
Prediction of apoptosis protein subcellular location based on amphiphilic pseudo amino acid composition Open
Introduction: Apoptosis proteins play an important role in the process of cell apoptosis, which makes the rate of cell proliferation and death reach a relative balance. The function of apoptosis protein is closely related to its subcellula…
View article: Genotypic Diversity and Antimicrobial Resistance of Escherichia Coli Isolated From Pigs in Hubei, China
Genotypic Diversity and Antimicrobial Resistance of Escherichia Coli Isolated From Pigs in Hubei, China Open
BackgroundIntestinal infections with Escherichia coli (E. coli) are mostly occur in piglets between 1~10 days old, which major lead to diarrhea and edema in newborn piglets . These diseases caused by E. coli can increase mortality, morbidi…
View article: Association of Adherent-invasive <i>Escherichia coli</i> with severe Gut Mucosal dysbiosis in Hong Kong Chinese population with Crohn’s disease
Association of Adherent-invasive <i>Escherichia coli</i> with severe Gut Mucosal dysbiosis in Hong Kong Chinese population with Crohn’s disease Open
Adherent invasive Escherichia Coli (AIEC) has been implicated in the pathogenesis of Crohn's disease (CD) in Western populations. Whether the presence of AIEC is also seen in CD populations of different genetic susceptibility and has negat…
View article: Spatiotemporal dynamics in excitable homogeneous random networks composed of periodically self-sustained oscillation
Spatiotemporal dynamics in excitable homogeneous random networks composed of periodically self-sustained oscillation Open
The collective behaviors of networks are often dependent on the network connections and bifurcation parameters, also the local kinetics plays an important role in contributing the consensus of coupled oscillators. In this paper, we systema…
View article: Effects of Supplemental Boron on Intestinal Proliferation and Apoptosis in African Ostrich Chicks
Effects of Supplemental Boron on Intestinal Proliferation and Apoptosis in African Ostrich Chicks Open
Boron is an essential trace element which plays an important role in process of metabolism and the function of the tissues.However, the effects of boron on the intestinal cells in African ostrich chicks are poorly reported.Therefore, this …
View article: Synchronization transition with coexistence of attractors in coupled discontinuous system
Synchronization transition with coexistence of attractors in coupled discontinuous system Open
The studies of extended dynamics systems are relevant to the understanding of spatiotemporal patterns observed in diverse fields. One of the well-established models for such complex systems is the coupled map lattices, and several features…
View article: Increased Thymic Cell Turnover under Boron Stress May Bypass TLR3/4 Pathway in African Ostrich
Increased Thymic Cell Turnover under Boron Stress May Bypass TLR3/4 Pathway in African Ostrich Open
Previous studies revealed that thymus is a targeted immune organ in malnutrition, and high-boron stress is harmful for immune organs. African ostrich is the living fossil of ancient birds and the food animals in modern life. There is no re…
View article: Clinical characteristics of patients with HBsAg(+) versus HBsAg(-)/HBcAb(+) primary hepatic carcinoma treated by hepatectomy: a comparative analysis
Clinical characteristics of patients with HBsAg(+) versus HBsAg(-)/HBcAb(+) primary hepatic carcinoma treated by hepatectomy: a comparative analysis Open
ObjectiveTo explore the differences in clinical characteristics between patients with HBsAg(+) and HBsAg(-)/HBcAb(+) primary hepatic carcinoma (PHC) treated by hepatectomy. MethodsForty-three HBsAg(+) and 18 HBsAg(-)/HBcAb(+) patients who …
View article: Period-adding bifurcations in a discontinuous system with a variable gap
Period-adding bifurcations in a discontinuous system with a variable gap Open
The period-adding bifurcations in a discontinuous system with a variable gap are observed for two control parameters. Various period-adding bifurcations are found by simulations. The bifurcation diagram can be divided into two different zo…