Kanglai He
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View article: Design, Synthesis, and Aphicidal Activity of Novel Insect Neuropeptide Kinin Receptor Antagonists, Targeting the Ser<sup>2</sup> Ligand Position
Design, Synthesis, and Aphicidal Activity of Novel Insect Neuropeptide Kinin Receptor Antagonists, Targeting the Ser<sup>2</sup> Ligand Position Open
Traditional chemical pesticides have raised significant environmental and health concerns, driving the pursuit of safer alternatives. Aphids, notorious for causing extensive agricultural damage and transmitting plant diseases, represent pr…
View article: Correction: Application of machine learning in predicting perioperative neurocognitive disorders in elderly patients: the impact of sarcopenia-related features
Correction: Application of machine learning in predicting perioperative neurocognitive disorders in elderly patients: the impact of sarcopenia-related features Open
[This corrects the article DOI: 10.3389/fmed.2025.1604333.].
View article: Application of machine learning in predicting perioperative neurocognitive disorders in elderly patients: the impact of sarcopenia-related features
Application of machine learning in predicting perioperative neurocognitive disorders in elderly patients: the impact of sarcopenia-related features Open
Background Older surgical patients present with diverse clinical profiles, yet research indicates a significant correlation between sarcopenia-related features and the incidence of perioperative neurocognitive disorder (PND). The integrati…
View article: The rise of Mendelian randomization for exploring disease causality: A bibliometric analysis based on CiteSpace
The rise of Mendelian randomization for exploring disease causality: A bibliometric analysis based on CiteSpace Open
Objective: Mendelian randomization (MR) utilizes genetic variants as instrumental variables to explore causal associations between exposures and outcomes. Despite a significant increase in MR-related publication volume in recent years, acc…
View article: Invasion Dynamics and Migration Patterns of Fall Armyworm (Spodoptera frugiperda) in Shaanxi, China
Invasion Dynamics and Migration Patterns of Fall Armyworm (Spodoptera frugiperda) in Shaanxi, China Open
The fall armyworm (Spodoptera frugiperda) is a highly invasive agricultural pest that has caused significant damage to maize and other crops since its initial detection in China in 2019. Understanding its invasion dynamics, migration patte…
View article: Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions
Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions Open
Mitochondrial dysfunction is increasingly recognized as a critical driver in the pathogenesis of cardiovascular diseases. Mitochondrial quality control (MQC) is an ensemble of adaptive mechanisms aimed at maintaining mitochondrial integrit…
View article: Chromosome-level genome of a multivoltine biotype Ostrinia furnacalis strain
Chromosome-level genome of a multivoltine biotype Ostrinia furnacalis strain Open
The Asian corn borer (Ostrinia furnacalis), a major economic pest of crops such as corn, sugarcane, millet, and sorghum, is widely distributed from Asia to the western Pacific islands. Its broad distribution and polyphagous traits are larg…
View article: Establishment and Validation of a Method for the Identification of Recessive Mastitis Resistance Genes in Dairy Cows
Establishment and Validation of a Method for the Identification of Recessive Mastitis Resistance Genes in Dairy Cows Open
Background/Objectives: The resistance to occult mastitis in dairy cows is a multifaceted trait influenced by a variety of genetic and environmental factors, posing significant challenges to its prevention and treatment. Methods: In this st…
View article: ZnO-Nafion assisted optical fiber dual-SPR biosensor for simultaneous detection of urea and uric acid concentrations
ZnO-Nafion assisted optical fiber dual-SPR biosensor for simultaneous detection of urea and uric acid concentrations Open
A novel dual-parameter optical fiber biosensor based on surface plasmon resonance (SPR) for simultaneous measurement of urea and uric acid concentrations is proposed in this paper. Based on the principle of positive and negative electric c…
View article: Targeting mitochondria by lipid-selenium conjugate drug results in malate/fumarate exhaustion and induces mitophagy-mediated necroptosis suppression
Targeting mitochondria by lipid-selenium conjugate drug results in malate/fumarate exhaustion and induces mitophagy-mediated necroptosis suppression Open
Atherosclerosis (AS) is a chronic vascular disease primarily affecting large and medium-sized arteries and involves various complex pathological mechanisms and factors. Previous studies have demonstrated a close association between atheros…
View article: Effects of host plants on aphid feeding behavior, fitness, and <i>Buchnera aphidicola</i> titer
Effects of host plants on aphid feeding behavior, fitness, and <i>Buchnera aphidicola</i> titer Open
Aphids are sap‐feeding plant pests that depend on their symbiotic relationships with the primary endosymbiont Buchnera aphidicola to adapt to impoverished diets. However, how the host plant affects the aphid primary symbiont and aphid adap…
View article: Toxicity of Cry- and Vip3Aa-Class Proteins and Their Interactions against Spodoptera frugiperda (Lepidoptera: Noctuidae)
Toxicity of Cry- and Vip3Aa-Class Proteins and Their Interactions against Spodoptera frugiperda (Lepidoptera: Noctuidae) Open
The fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith), is one of the most important insect pests affecting corn crops worldwide. Although planting transgenic corn expressing Bacillus thuringiensis (Bt) toxins has been approved as bei…
View article: Multiple-omics techniques reveal the difference between polyphagous Conogethes punctiferalis and oligophagous C. pinicolalis
Multiple-omics techniques reveal the difference between polyphagous Conogethes punctiferalis and oligophagous C. pinicolalis Open
Although Conogethes punctiferalis and Conogethes pinicolalis have reported on morphology and molecular identification, the molecular biology differences between the two species in different diets are still unknown. In this work, we investi…
View article: Genetic knockout and general odorant binding/chemosensory proteins interactions: revealed the function and importance of GOBP2 in the yellow peach moth olfactory system
Genetic knockout and general odorant binding/chemosensory proteins interactions: revealed the function and importance of GOBP2 in the yellow peach moth olfactory system Open
The GOBP2 protein has a unique function in the yellow peach moth, Conogethes punctiferalis. Several general odorant binding proteins (GOBPs) have been identified in various lepidopteran species, but the functional difference between GOBP1 …
View article: Evolutionary Shift of Insect Diapause Strategy in a Warming Climate: An Intra-Population Evidence from Asian Corn Borer
Evolutionary Shift of Insect Diapause Strategy in a Warming Climate: An Intra-Population Evidence from Asian Corn Borer Open
Herbivorous insects having variable numbers of generations annually depending on climate and day length conditions are increasingly breeding additional generations driven by elevated temperature under the scenario of global warming, which …
View article: sympatric voltinetypes and their response to climate warming in Asian corn borer
sympatric voltinetypes and their response to climate warming in Asian corn borer Open
Voltinism in facultative diapause insect can be shift by temperature and photoperiod. Climate warming could drive individuals that used to be univoltinism shift to bivoltinism due to compensatory effect of elevated temperature. Asian corn …
View article: Seven Years of Monitoring Susceptibility to Cry1Ab and Cry1F in Asian Corn Borer
Seven Years of Monitoring Susceptibility to Cry1Ab and Cry1F in Asian Corn Borer Open
Resistance monitoring in the Asian corn borer, Ostrinia furnacalis, is necessary to accommodate the commercial introduction and stewardship of Bt maize in China. The susceptibility of 56 O. furnacalis field populations, collected between 2…
View article: Secondary symbionts affect aphid fitness and the titer of primary symbiont
Secondary symbionts affect aphid fitness and the titer of primary symbiont Open
Bacterial symbionts associated with aphids are important for their ecological fitness. The corn leaf aphid, Rhopalosiphum maidis (Fitch), is one of the most damaging aphid pests on maize and has been reported to harbor Hamiltonella defensa…
View article: Intra-Population Alteration on Voltinism of Asian Corn Borer in Response to Climate Warming
Intra-Population Alteration on Voltinism of Asian Corn Borer in Response to Climate Warming Open
The Asian corn borer (ACB) Ostrinia furnacalis (Guenée) can occur in one to seven generations annually from cool (48°00′ N) to warm (18°10′ N) region of corn cultivation in China. Although ACB is commonly known as a facultative larval diap…
View article: Rotation of Multiple Single-Gene Transgenic Crops Did Not Slow the Evolution of Resistance to Cry1F or Cry1Ie in Ostrinia furnacalis
Rotation of Multiple Single-Gene Transgenic Crops Did Not Slow the Evolution of Resistance to Cry1F or Cry1Ie in Ostrinia furnacalis Open
A common strategy for delaying the evolution of resistance to transgenic crops that produce insecticidal proteins from Bacillus thuringiensis is to ensure that insect pests are exposed to multiple toxins with different mechanisms of action…
View article: Analysis of the Genetic Diversity of Two Rhopalosiphum Species from China and Europe Based on Nuclear and Mitochondrial Genes
Analysis of the Genetic Diversity of Two Rhopalosiphum Species from China and Europe Based on Nuclear and Mitochondrial Genes Open
Population genetic studies can reveal clues about the evolution of adaptive strategies of aphid species in agroecosystems and demonstrate the influence of environmental factors on the genetic diversity and gene flow among aphid populations…
View article: Hemocyte response to treatment of susceptible and resistant Asian corn borer (Ostrinia furnacalis) larvae with Cry1F toxin from Bacillus thuringiensis
Hemocyte response to treatment of susceptible and resistant Asian corn borer (Ostrinia furnacalis) larvae with Cry1F toxin from Bacillus thuringiensis Open
Midgut receptors have been recognized as the major mechanism of resistance to Cry proteins in lepidopteran larvae, while there is a dearth of data on the role of hemocyte’s response to Cry intoxication and resistance development. We aimed …
View article: Transcription dynamics of heat shock proteins in response to thermal acclimation in Ostrinia furnacalis
Transcription dynamics of heat shock proteins in response to thermal acclimation in Ostrinia furnacalis Open
Acclimation to abiotic stress plays a critical role in insect adaption and evolution, particularly during extreme climate events. Heat shock proteins (HSPs) are evolutionarily conserved molecular chaperones caused by abiotic and biotic str…
View article: Loss of parasitoid diversity in China’s corn agro-ecosystem over a 30-year time period
Loss of parasitoid diversity in China’s corn agro-ecosystem over a 30-year time period Open
Globally, insects are undergoing a rapid decline in abundance and diversity. Despite varying degrees of scientific attention across insect taxa and geographies, these patterns can entail an extinction of ecological interactions and a decay…
View article: Inheritance and Fitness Costs of Vip3Aa19 Resistance in Mythimna separata
Inheritance and Fitness Costs of Vip3Aa19 Resistance in Mythimna separata Open
The “high-dose/refuge” strategy is expected to work most effectively when resistance is inherited as a functionally recessive trait and the fitness costs associated with resistance are present. In the present study, a laboratory selected M…
View article: Baseline Susceptibility and Resistance Allele Frequency in Ostrinia furnacalis in Relation to Cry1Ab Toxins in China
Baseline Susceptibility and Resistance Allele Frequency in Ostrinia furnacalis in Relation to Cry1Ab Toxins in China Open
Asian corn borer (ACB), Ostrinia furnacalis (Guenée) is a destructive pest of corn and major target of transgenic corn expressing Bt (Bacillus thuringiensis) toxins in China. It is necessary to establish the baseline susceptibility of geog…