Lixing Lao
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View article: Cardiomyocyte cytosolic nuclear self-DNA contributes to the pathogenesis of desmoplakin cardiomyopathy
Cardiomyocyte cytosolic nuclear self-DNA contributes to the pathogenesis of desmoplakin cardiomyopathy Open
Hereditary cardiomyopathies are the prototypic forms of heart failure and major causes of sudden cardiac death. The genome in cardiomyopathies is exposed to internal stressors, which damage the DNA and activate the DNA damage response (DDR…
View article: Acupuncture Improves MRI Brain Microstructure with Postconcussion Symptoms in Mild TBI: A Randomized Controlled Trial
Acupuncture Improves MRI Brain Microstructure with Postconcussion Symptoms in Mild TBI: A Randomized Controlled Trial Open
Acupuncture, a nonpharmacologic therapy, effectively reduced acute postconcussion symptom severity and alleviated long-term neurologic impairments in participants with mild traumatic brain injury.
View article: Nosocomial infections after acupuncture and related therapies: A systematic review of case reports and case series
Nosocomial infections after acupuncture and related therapies: A systematic review of case reports and case series Open
Background: Acupuncture and its related therapies, as an important part of traditional Chinese medicine, have been widely accepted by the public and healthcare professionals all over the world. According to previous reviews, the department…
View article: GR00T N1: An Open Foundation Model for Generalist Humanoid Robots
GR00T N1: An Open Foundation Model for Generalist Humanoid Robots Open
General-purpose robots need a versatile body and an intelligent mind. Recent advancements in humanoid robots have shown great promise as a hardware platform for building generalist autonomy in the human world. A robot foundation model, tra…
View article: The State of 21st Century Acupuncture in the United States
The State of 21st Century Acupuncture in the United States Open
The term "acupuncture" commonly refers to a non-pharmacologic therapy that is increasingly employed by diverse segments of the population for a wide variety of complaints including pain, insomnia, anxiety, depression, frozen shoulder, and …
View article: Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults
Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults Open
Importance The effects of self-administered acupressure (SAA) on knee osteoarthritis (OA) pain remain unclear. Objective To evaluate the effectiveness of SAA taught via a short training course on reducing knee OA pain in middle-aged and ol…
View article: The SHARE: SHam Acupuncture REporting guidelines and a checklist in clinical trials
The SHARE: SHam Acupuncture REporting guidelines and a checklist in clinical trials Open
Sham acupuncture is commonly utilized as the control to evaluate the specific effects of acupuncture. Due to the complexity of acupuncture, establishing sham acupuncture control to maintain physiological inertness while indistinguishable f…
View article: Electroacupuncture for Pain Relief After Endoscopic Sinus Surgery: A Randomized Controlled Trial
Electroacupuncture for Pain Relief After Endoscopic Sinus Surgery: A Randomized Controlled Trial Open
Postoperative pain is a common problem after endoscopic sinus surgery (ESS). Electroacupuncture (EA) is proven to be effective in relieving postoperative pain. However, EA has not been studied in patients undergoing ESS. This study was des…
View article: Add-on Rehmannia-6–Based Chinese Medicine in Type 2 Diabetes and CKD
Add-on Rehmannia-6–Based Chinese Medicine in Type 2 Diabetes and CKD Open
Background Diabetes is the leading cause of CKD and kidney failure. We assessed the real-world effectiveness of Rehmannia-6–based Chinese medicine treatment, the most used Chinese medicine formulation, on the change in eGFR and albuminuria…
View article: Mapping of Spatiotemporal Auricular Electrophysiological Signals Reveals Human Biometric Clusters
Mapping of Spatiotemporal Auricular Electrophysiological Signals Reveals Human Biometric Clusters Open
Underneath the ear skin there are rich vascular network and sensory nerve branches. Hence, the 3D mapping of auricular electrophysiological signals can provide new biomedical perspectives. However, it is still extremely challenging for cur…
View article: The Effectiveness of Liu Zi Jue Exercise for Chronic Obstructive Pulmonary Disease (COPD): Systematic Review and Meta-analysis of Randomized Controlled Trials
The Effectiveness of Liu Zi Jue Exercise for Chronic Obstructive Pulmonary Disease (COPD): Systematic Review and Meta-analysis of Randomized Controlled Trials Open
Background Liuzijue (LZJ), one of the traditional Chinese exercises, may influence the patients’ quality of life and pulmonary function, hence it might have beneficial effects in the treatment of chronic obstructive pulmonary disease (COPD…
View article: How to design high quality acupuncture trials—a consensus informed by evidence
How to design high quality acupuncture trials—a consensus informed by evidence Open
An international panel including patients, clinicians, researchers, acupuncture and surgery trialists, statisticians, and experts in clinical epidemiology and methodology have developed new guidance for randomised controlled trials in acup…
View article: Methodological challenges in design and conduct of randomised controlled trials in acupuncture
Methodological challenges in design and conduct of randomised controlled trials in acupuncture Open
Yu-Tong Fei and colleagues examine the problems with designing and implementing trials of acupuncture
View article: Guideline Acupuncture for low back pain: a clinical practice guideline from the Hong Kong taskforce of standardized acupuncture practice.
Guideline Acupuncture for low back pain: a clinical practice guideline from the Hong Kong taskforce of standardized acupuncture practice. Open
A clinical practice guideline for acupuncture treating low back pain was developed based on contemporary clinical evidence and experts' consensus to provide best currently agreeable practice guideline for domestic and international stakeho…
View article: Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Integrative oncology: Addressing the global challenges of cancer prevention and treatment Open
The increase in cancer incidence and mortality is challenging current cancer care delivery globally, disproportionally affecting low‐ and middle‐income countries (LMICs) when it comes to receiving evidence‐based cancer prevention, treatmen…
View article: Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients
Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients Open
Objective. To investigate the potential benefits and safety of acupuncture on managing side effects induced by drug therapies in patients with breast cancer using a PRISMA standard systematic review and meta-analysis. Methods. Published ra…
View article: Dopaminergic signaling in prefrontal cortex contributes to the antidepressant effect of electroacupuncture: An <scp>iTRAQ‐based</scp> proteomics analysis in a rat model of <scp>CUMS</scp>
Dopaminergic signaling in prefrontal cortex contributes to the antidepressant effect of electroacupuncture: An <span>iTRAQ‐based</span> proteomics analysis in a rat model of <span>CUMS</span> Open
Electroacupuncture (EA) is used as an adjunctive treatment for depression. This study was conducted to evaluate the efficacy and mechanisms of EA in the depressive rat model induced by chronic unpredictable mild stress (CUMS) in male adult…
View article: The prevalence of depression and its association with the risk of mortality in patients with cancer：a protocol for systematic review and meta analysis
The prevalence of depression and its association with the risk of mortality in patients with cancer：a protocol for systematic review and meta analysis Open
Review question / Objective: 1. Types of studies: Crosssectional, cohort and case-control studies will be included, while the case reports, reviews, editorials, abstracts of conferences, and letter to the editors will be excluded.2. Types …
View article: Graphene-based Distributed 3D Sensing Electrodes for Mapping Spatiotemporal Auricular Physiological Signals
Graphene-based Distributed 3D Sensing Electrodes for Mapping Spatiotemporal Auricular Physiological Signals Open
Underneath the ear skin there are richly branching vascular and neural networks that ultimately connecting to our heart and brain. Hence, the three-dimensional (3D) mapping of auricular electrophysiological signals could provide a new pers…
View article: Effects of Acupuncture on Vascular Cognitive Impairment with No Dementia: A Randomized Controlled Trial
Effects of Acupuncture on Vascular Cognitive Impairment with No Dementia: A Randomized Controlled Trial Open
Background: Acupuncture has been used for treating vascular cognitive impairment, but evidence for its effectiveness remains limited. Objective: This single-center, patient-accessor blinded, randomized controlled trial was designed to asse…
View article: Electroacupuncture Plus Auricular Acupressure for Chemotherapy-Associated Insomnia in Breast Cancer Patients: A Pilot Randomized Controlled Trial
Electroacupuncture Plus Auricular Acupressure for Chemotherapy-Associated Insomnia in Breast Cancer Patients: A Pilot Randomized Controlled Trial Open
Objective: Chemotherapy-associated insomnia is a highly prevalent complaint in breast cancer patients. This study was undertaken to evaluate the safety, feasibility, and preliminary effectiveness of electroacupuncture plus auricular acupre…
View article: Effect of a medicinal and edible decoction YH0618 on chemotherapy-induced dermatologic toxicity: a randomized controlled trial
Effect of a medicinal and edible decoction YH0618 on chemotherapy-induced dermatologic toxicity: a randomized controlled trial Open
The trial was registered in the Chinese Clinical Trials Registry, ChiCTR-IOR-15006486.