Longjiang Li
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View article: Spatial Transcriptomics Reveals Tgfβ1–Orchestrated Periodontium Stem Cell Senescence
Spatial Transcriptomics Reveals Tgfβ1–Orchestrated Periodontium Stem Cell Senescence Open
Aim or purpose: This study investigates the role of TGF-β1 in periodontal ligament stem cell (PDLSC) senescence and elucidates the underlying molecular mechanisms, enhancing our current understanding of age-related periodontal diseases. Ma…
View article: RETRACTED: Zhang et al. Strength Analysis and Reinforcement of 120 m3 Liquid Helium Storage Tank for Transportation Case. Processes 2025, 13, 100
RETRACTED: Zhang et al. Strength Analysis and Reinforcement of 120 m3 Liquid Helium Storage Tank for Transportation Case. Processes 2025, 13, 100 Open
The journal retracts and removes the article titled “Strength Analysis and Reinforcement of 120 m3 Liquid Helium Storage Tank for Transportation Case” [...]
View article: Dasatinib and Quercetin Mitigate Age‐Related Alveolar Bone Inflammaging and Neutrophil Infiltration
Dasatinib and Quercetin Mitigate Age‐Related Alveolar Bone Inflammaging and Neutrophil Infiltration Open
Objective Age‐related alveolar bone resorption poses a major dental health challenge, yet its mechanisms and treatments are poorly understood. This study investigates the impact of dasatinib and quercetin (D + Q) treatment on senescent cel…
View article: Numerical Study on Heat Leakage, Thermal Stratification, and Self-Pressurization Characteristics in Liquid Helium Storage Tanks
Numerical Study on Heat Leakage, Thermal Stratification, and Self-Pressurization Characteristics in Liquid Helium Storage Tanks Open
During the operation of liquid-phase He-4 (LHe-4) storage tanks, heat leakage changes the thermophysical parameters and phase properties of the LHe-4 in the tanks, resulting in the thermal layering phenomenon. This phenomenon is characteri…
View article: <scp>SCG2</scp> Mediates <scp>HNSCC</scp> Progression With <scp>CCL2</scp> / <scp> TGFβ1 <sup>high</sup> M2 </scp> Macrophage Infiltration
<span>SCG2</span> Mediates <span>HNSCC</span> Progression With <span>CCL2</span> / <span> TGFβ1 <sup>high</sup> M2 </span> Macrophage Infiltration Open
Objectives This study aims to unravel the mechanisms underlying M2 macrophage polarization in head and neck squamous cell carcinoma (HNSCC), and identify potential therapeutic targets. Materials and Methods We conducted an integrated bioin…
View article: [A single-center analysis of pathogenic bacteria distribution and drug resistance in bacterial bloodstream infections among patients with hematological diseases].
[A single-center analysis of pathogenic bacteria distribution and drug resistance in bacterial bloodstream infections among patients with hematological diseases]. Open
Objective: To analyze the distribution and drug resistance of pathogens of bacterial bloodstream infection in patients with hematological diseases in the Department of Hematology of Tianjin Medical University General Hospital, and to provi…
View article: TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells
TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells Open
Breast cancer ranks the first in the incidence of female cancer and is the most common cancer threatening the life and health of women worldwide.Tumor protein p53-regulated apoptosis-inducing protein 1 (TP53AIP1) is a pro-apoptotic gene do…
View article: Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma
Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma Open
Cancer cells with mitochondrial dysfunction can be rescued by cells in the tumor microenvironment. Using human adenoid cystic carcinoma cell lines and fibroblasts, we find that mitochondrial transfer occurs not only between human cells but…
View article: Study on the Hydrophobic Modification Mechanism of Stearic Acid on the Surface of Coal Gasification Fly Ash
Study on the Hydrophobic Modification Mechanism of Stearic Acid on the Surface of Coal Gasification Fly Ash Open
In this study, the hydrophobic modification of coal gasification fly ash (FA) was investigated given the adverse effects of surface hydrophilic structures on the material field. The surface of FA was modified using stearic acid (SA), which…
View article: Cancer cell-derived exosomal miRNA induces and reprograms Schwann cells to augment the perineural invasion of salivary adenoid cystic carcinoma
Cancer cell-derived exosomal miRNA induces and reprograms Schwann cells to augment the perineural invasion of salivary adenoid cystic carcinoma Open
To the Editor: Salivary adenoid cystic carcinoma (SACC) is characterized by the high frequency of perineural invasion (PNI) behavior during tumor progression. However, the impact of intercellular communication between SACC cells and surrou…
View article: A Brown Dwarf Orbiting around the Planetary-nebula Central Binary KV Vel
A Brown Dwarf Orbiting around the Planetary-nebula Central Binary KV Vel Open
KV Vel is a noneclipsing short-period ( P = 0.3571 days) close binary containing a very hot subdwarf primary (77,000 K) and a cool low-mass secondary star (3400 K) that is located at the center of the planetary nebula DS 1. The changes in …
View article: Functional and aesthetic results of the Z-shaped and straight lower lip-splitting incision: a randomized clinical trial
Functional and aesthetic results of the Z-shaped and straight lower lip-splitting incision: a randomized clinical trial Open
The lip-splitting approach enables excellent access to all areas of the mouth and pharynx to remove tumors; however, traditional lower lip-splitting incisions produce an unsatisfactory scar. To achieve better functional and aesthetic resul…
View article: Icariin Mitigates the Growth and Invasion Ability of Human Oral Squamous Cell Carcinoma via Inhibiting Toll-Like Receptor 4 and Phosphorylation of NF-κB P65 [Retraction]
Icariin Mitigates the Growth and Invasion Ability of Human Oral Squamous Cell Carcinoma via Inhibiting Toll-Like Receptor 4 and Phosphorylation of NF-κB P65 [Retraction] Open
[This retracts the article DOI: 10.2147/OTT.S214514.].
View article: Deletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice
Deletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice Open
Background Enhanced glycolysis is a crucial metabolic event that drives the development of liver fibrosis, but the molecular mechanisms have not been fully understood. Lactate is the endproduct of glycolysis, which has recently been identi…
View article: A comprehensive review of superconductivity in heterostructures and superlattices comprising 2D materials
A comprehensive review of superconductivity in heterostructures and superlattices comprising 2D materials Open
2D materials are materials that only exist in two dimensions, which means that their thickness is only one atom or several atoms. Since the first kind of 2D material was found, which is graphene, much research, not only including the findi…
View article: Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review
Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review Open
Background: Due to the rapid development of nanotechnology and nanocomplex synthetic techniques, a large number of nanoparticle-based cancer medicines have been evaluated or applied in clinical trials for utility. However, the quality, eff…
View article: Chinese surgical robot-assisted surgery for parotid tumor: a case report.
Chinese surgical robot-assisted surgery for parotid tumor: a case report. Open
Robotic surgery is known as the "third technological revolution" in the field of surgery, and is an important milestone in the development of modern surgery. However, our country's innovative surgical robot industry is still in its early s…
View article: Mechanism of Phosphate Desorption from Activated Red Mud Particle Adsorbents
Mechanism of Phosphate Desorption from Activated Red Mud Particle Adsorbents Open
Herein, activated red mud particles are used as adsorbents for phosphorus adsorption. HCl solutions with different concentrations and deionized water are employed for desorption tests, and the desorption mechanism under the following optim…
View article: The Potential Role and Therapeutic Relevance of Cellular Senescence in Skeletal Pathophysiology
The Potential Role and Therapeutic Relevance of Cellular Senescence in Skeletal Pathophysiology Open
Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The underlying mechanisms of cellular senescence, triggered by bot…
View article: Agrimol B alleviates cisplatin-induced acute kidney injury by activating the Sirt1/Nrf2 signaling pathway in mice
Agrimol B alleviates cisplatin-induced acute kidney injury by activating the Sirt1/Nrf2 signaling pathway in mice Open
Cisplatin (CDDP) is a widely used chemotherapeutic agent that has remarkable antineoplastic effects. However, CDDP can cause severe acute kidney injury (AKI), which limits its clinical application. Agrimol B is the main active ingredient f…
View article: Mechanism of Phosphate Desorption from Activated Red Mud Particle Adsorbents
Mechanism of Phosphate Desorption from Activated Red Mud Particle Adsorbents Open
Herein, activated red mud particles are used as an adsorbent for adsorbing phosphorus. Different concentrations of HCl and deionized water are used for desorption tests, and the optimal desorption mechanism is investigated. The Langmuir is…
View article: Formulation Optimization and Performance Prediction of Red Mud Particle Adsorbents Based on Neural Networks
Formulation Optimization and Performance Prediction of Red Mud Particle Adsorbents Based on Neural Networks Open
Red mud (RM), a bauxite residue, contains hazardous radioactive wastes and alkaline material and poses severe surface water and groundwater contamination risks, necessitating recycling. Pretreated RM can be used to make adsorbents for wate…
View article: Investigations of thermohydraulic performance in heat exchanger tube with rectangular vortex generators
Investigations of thermohydraulic performance in heat exchanger tube with rectangular vortex generators Open
To demonstrate the rationalization of multi-longitudinal swirls in heat exchanger tubes, this paper investigates the thermohydraulic performance of heat exchanger tube with rectangular vortex generator using numerical simulation. Comparati…
View article: Numerical simulation study of enhanced convective heat transfer in the tube based on winglet vortex generator
Numerical simulation study of enhanced convective heat transfer in the tube based on winglet vortex generator Open
In order to enhance the heat transfer effect and improve the energy utilization efficiency of the circular tube under turbulent flow, rhombic and triangular winglet vortex generators are proposed on the basis of rectangular winglet vortex …
View article: The therapeutic efficacy of different configuration nano-polydopamine drug carrier systems with photothermal synergy against head and neck squamous cell carcinoma
The therapeutic efficacy of different configuration nano-polydopamine drug carrier systems with photothermal synergy against head and neck squamous cell carcinoma Open
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignant tumor worldwide. Considering its special anatomical site and the progressive resistance to chemotherapy drugs, the development of more effective, minimally in…
View article: Numerical simulation study of enhanced convective heat transfer in the tube based on winglet vortex generator
Numerical simulation study of enhanced convective heat transfer in the tube based on winglet vortex generator Open
In order to enhance the heat transfer effect and improve the energy utilization efficiency of the circular tube under turbulent flow, rhombic and triangular winglet vortex generators are proposed on the basis of rectangular winglet vortex …
View article: <scp>TTC7B</scp> is a new prognostic biomarker in head and neck squamous cell carcinoma linked to immune infiltration and ferroptosis
<span>TTC7B</span> is a new prognostic biomarker in head and neck squamous cell carcinoma linked to immune infiltration and ferroptosis Open
Objective To investigate the expression of TTC7B and its prognostic significance, biological roles, and impact on the immune system in patients with head and neck squamous cell carcinoma (HNSCC). Materials and Methods Clinical and genomic …