Duo Li
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View article: A scalable, hyperstable intelligent fibre velocimeter for dynamic digitisation of resistance training
A scalable, hyperstable intelligent fibre velocimeter for dynamic digitisation of resistance training Open
Real-time accuracy and continuous dynamic monitoring capability of devices are crucial for the scientific configuration and dynamic modulation of resistance training, such as strength training, rehabilitation, and in-orbit training for ast…
View article: Advances in clinical research on interstitial lung disease
Advances in clinical research on interstitial lung disease Open
Interstitial lung disease (ILD) is a group of pulmonary disorders characterized by complex etiologies and diverse clinical manifestations, with an increasing incidence trend. This article aims to review the cutting-edge research on ILD, in…
View article: SMK-002 inhibits the growth of bladder cancer cells and increases their sensitivity to Osimertinib <i>via</i> enhancing epidermal growth factor receptor degradation
SMK-002 inhibits the growth of bladder cancer cells and increases their sensitivity to Osimertinib <i>via</i> enhancing epidermal growth factor receptor degradation Open
SMK-002, a novel derivative of proguanil, has higher inhibitory activity against cancer than proguanil. We previously found that SMK-002 significantly inhibited the proliferation of bladder cancer (BC) cells. In this study, we creatively f…
View article: Metabolomic and metagenomic analyses reveal distinct microenvironmental signatures between clear aligner–associated and tooth surface dental plaque
Metabolomic and metagenomic analyses reveal distinct microenvironmental signatures between clear aligner–associated and tooth surface dental plaque Open
Objective Clear aligners (CAs) create unique oral microenvironments that may alter oral microbial metabolism, potentially increasing the risk of disease. However, metabolomic differences between CA-facing and tooth surface plaque remain un…
View article: Brain–behavior relationships in task-based fMRI assessments of executive functions in children and adolescents with and without ADHD: a systematic review and ALE meta-analysis
Brain–behavior relationships in task-based fMRI assessments of executive functions in children and adolescents with and without ADHD: a systematic review and ALE meta-analysis Open
The results of this study enhance our understanding of ADHDs pathophysiology and suggest potential pathways for developing interventions and therapies.
View article: Superiority of a combined antithrombin and activated protein C model for predicting coagulopathy and mortality in pneumonia-related sepsis: A prospective cohort study
Superiority of a combined antithrombin and activated protein C model for predicting coagulopathy and mortality in pneumonia-related sepsis: A prospective cohort study Open
In conclusion, this preliminary study identifies a combined AT/aPC model as a promising early predictor of DIC progression and mortality in pneumonia-sepsis. If validated in larger, multicentre cohorts, this simple two-biomarker approach p…
View article: Soy Protein Outperforms Whey Protein in Ameliorating Insulin Resistance but Not Obesity in High-Fat Diet-Induced Obese Mice
Soy Protein Outperforms Whey Protein in Ameliorating Insulin Resistance but Not Obesity in High-Fat Diet-Induced Obese Mice Open
Background/Objectives: To date, few studies have investigated the therapeutic effects of soy versus whey protein supplementation on obesity and insulin resistance (IR), yielding inconsistent findings. The aim of the present study was to co…
View article: Shedding light on the darkness: cryptic diversity of cordyceps-like fungi in karst regions of Guizhou Province, China
Shedding light on the darkness: cryptic diversity of cordyceps-like fungi in karst regions of Guizhou Province, China Open
Cordyceps-like fungi are abundant in karst regions in Guizhou Province, China, but systematic investigations are still lacking. In this study, species diversity of cordyceps-like fungi in karst habitats, forests, Tiankeng regions and valle…
View article: The effectiveness of symptom-oriented mind mapping combined with problem-based learning in critical care clerkships: a randomized controlled trial
The effectiveness of symptom-oriented mind mapping combined with problem-based learning in critical care clerkships: a randomized controlled trial Open
Objective This study evaluated the efficacy of Symptom-Oriented Mind Mapping combined with Problem-Based Learning (SOM-PBL) in intensive care unit (ICU) clinical clerkships, assessing its impact on medical students’ knowledge integration, …
View article: Apple polyphenols alleviate hyperuricemia by inhibiting xanthine oxidase and promoting uric acid excretion
Apple polyphenols alleviate hyperuricemia by inhibiting xanthine oxidase and promoting uric acid excretion Open
Hyperuricemia, a metabolic disorder caused by excessive uric acid accumulation, is a major risk factor for gout and related kidney damage. Current pharmacological treatments often have side effects, emphasizing the need for safer alternati…
View article: Probiotics in the prevention and treatment of calcium oxalate kidney stones: mechanisms and therapeutic potential
Probiotics in the prevention and treatment of calcium oxalate kidney stones: mechanisms and therapeutic potential Open
Background Kidney stones, particularly calcium oxalate stones, remain a significant health issue despite advances in treatment techniques. Residual stones that persist after treatment can lead to recurrent stone formation and further compl…
View article: Comparative Evaluation of Remimazolam Besylate versus Propofol for Pediatric MRI Sedation: Safety, Recovery, and Adverse Event Profiles
Comparative Evaluation of Remimazolam Besylate versus Propofol for Pediatric MRI Sedation: Safety, Recovery, and Adverse Event Profiles Open
This study was prospectively registered with the Chinese Clinical Trial Registry (ChiCTR), registration number: ChiCTR2500097093.
View article: Poetic Bridge Without Borders: An Analysis of the Landscape and Roles in the Cross-Cultural Interaction between Yevgeny Yevtushenko and Chinese Scholars
Poetic Bridge Without Borders: An Analysis of the Landscape and Roles in the Cross-Cultural Interaction between Yevgeny Yevtushenko and Chinese Scholars Open
This study focuses on the cross-cultural interaction between the Russian poet Yevgeny Yevtushenko and the Chinese literary community. Unlike existing research that emphasizes the translation and reception of his works, this paper highlight…
View article: Thoracic blunt trauma causing fatal cardiac rupture and aortic dissection: A narrative review
Thoracic blunt trauma causing fatal cardiac rupture and aortic dissection: A narrative review Open
Thoracic blunt injuries are not uncommon, and they can cause severe cardiac and major vascular damage, leading to high mortality. Blunt cardiac rupture and traumatic aortic dissection are the primary fatal outcomes of these injuries. Many …
View article: 4D-DIA Proteomic Analysis of IPEC-J2 Cells Infected with Porcine Group A Rotavirus G9P[23] Strain
4D-DIA Proteomic Analysis of IPEC-J2 Cells Infected with Porcine Group A Rotavirus G9P[23] Strain Open
Porcine rotavirus (PoRV) is one of the most devastating enteric pathogens causing gastroenteritis in pigs, particularly the sudden occurrence in recent years in China. To elucidate host–pathogen interactions and molecular mechanisms underl…
View article: Postprandial Variability in Plasma Long-Chain Omega-3 is Independent of Supplement Lipid Structure
Postprandial Variability in Plasma Long-Chain Omega-3 is Independent of Supplement Lipid Structure Open
Objectives: Postprandial variations in plasma triacylglycerol (TAG) responses to veg-etable oils are well established, but their origins remain unclear. This study examined the variability of postprandial plasma long-chain omega-3 fatty ac…
View article: Association of lactate to albumin ratio with short-term and long-term mortality in critically ill patients with heart failure complicated by sepsis: a retrospective study using the MIMIC-IV database
Association of lactate to albumin ratio with short-term and long-term mortality in critically ill patients with heart failure complicated by sepsis: a retrospective study using the MIMIC-IV database Open
Background Elevated lactate to albumin ratio (LAR) has been associated with poor prognosis in critical illnesses. However, evidence regarding LAR in patients with heart failure (HF) complicated by sepsis remains limited. This study aimed t…
View article: Effects of Barbell Squats with Asymmetric Loading on the Joint Moment and Muscle Activity of Lower Limbs
Effects of Barbell Squats with Asymmetric Loading on the Joint Moment and Muscle Activity of Lower Limbs Open
This study aimed to investigate the effects of barbell squats with asymmetric loading on bilateral joint moments and muscle activity of the lower limbs. Twenty fitness athletes were recruited to perform squats under five different conditio…
View article: The triglyceride-glucose index is associated with coronary plaque features and clinical outcomes in patients with ST-segment elevation myocardial infarction
The triglyceride-glucose index is associated with coronary plaque features and clinical outcomes in patients with ST-segment elevation myocardial infarction Open
Background The triglyceride-glucose (TyG) index is a reliable surrogate marker for insulin resistance, and is associated with cardiovascular diseases. However, the specific impact of TyG index on coronary plaque vulnerability and long-term…
View article: Age-Related Changes in Theory of Mind in Middle Childhood: A Cross-Cultural Comparison Between Australian and Chinese Children
Age-Related Changes in Theory of Mind in Middle Childhood: A Cross-Cultural Comparison Between Australian and Chinese Children Open
Theory of mind (ToM) is centrally important in everyday social communication and interactions, and a growing number of studies have focused on this social-cognitive construct in school-aged children. This study explored age-related changes…
View article: Clinical features and mortality risk factors in non-HIV elderly patients with cryptococcal meningitis: A retrospective cohort study from 2013 to 2022
Clinical features and mortality risk factors in non-HIV elderly patients with cryptococcal meningitis: A retrospective cohort study from 2013 to 2022 Open
Background Cryptococcal meningitis (CM) is a life-threatening fungal infection with increasing incidence among non-HIV (human immunodeficiency virus) elderly populations. However, data on CM in non-HIV elderly patients are limited. This st…
View article: Role of Trimethylamine N‐Oxide in Assessing Plaque Instability of the Culprit Lesion in Chinese Patients With <scp>ST</scp>‐Elevation Myocardial Infarction: Insights From a 7‐Year Long‐Term Follow‐Up Study
Role of Trimethylamine N‐Oxide in Assessing Plaque Instability of the Culprit Lesion in Chinese Patients With <span>ST</span>‐Elevation Myocardial Infarction: Insights From a 7‐Year Long‐Term Follow‐Up Study Open
This study investigated the relationship between trimethylamine N‐oxide (TMAO) levels and plaque instability in Chinese patients with ST‐elevation myocardial infarction (STEMI) using optical coherence tomography (OCT), with a 7 ‐year follo…
View article: Nursing interventions’ impact on cardiovascular complications after gastrointestinal surgery in intensive care unit: Risk factor analysis
Nursing interventions’ impact on cardiovascular complications after gastrointestinal surgery in intensive care unit: Risk factor analysis Open
BACKGROUND Cardiovascular (CV) complications are common in intensive care unit (ICU) patients after gastrointestinal surgery and are associated with increased mortality and prolonged hospital stay. The optimization of postoperative nursing…
View article: Therapeutic landscape of ovarian cancer: recent advances and emerging therapies
Therapeutic landscape of ovarian cancer: recent advances and emerging therapies Open
Ovarian cancer ranks as the seventh most common malignancy and the eighth leading cause of cancer-related death in women worldwide. Most patients are diagnosed at an advanced stage, resulting in poor survival outcomes. The standard treatme…