Liam Urich
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View article: A recombinant expression system for the <i>Plasmodium falciparum</i> proteasome enables structural analysis of its assembly and the design of selective inhibitors
A recombinant expression system for the <i>Plasmodium falciparum</i> proteasome enables structural analysis of its assembly and the design of selective inhibitors Open
The Plasmodium falciparum 20S proteasome (Pf20S) has emerged as a promising antimalarial target. Development of therapeutics to this target has previously relied on native purifications of Pf20S, which is challenging and has limited the sc…