Yiqing Wu
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View article: Cell membrane damage, energy dissipation and ergosterol biosynthesis dysfunction induced by <i>trans</i> -4-methoxycinnamaldehyde inhibits <i>Penicillium digitatum</i> growth
Cell membrane damage, energy dissipation and ergosterol biosynthesis dysfunction induced by <i>trans</i> -4-methoxycinnamaldehyde inhibits <i>Penicillium digitatum</i> growth Open
Citrus green mold (CGM), caused by Penicillium digitatum, is a highly destructive fungal disease that impacts the citrus fruit industry on a global scale, leading to substantial economic losses. As a cinnamaldehyde derivative, trans-4-meth…
View article: PD-L1 expression in primary lung tumor as a superior predictive biomarker to metastatic lymph nodes for first-line immunochemotherapy in advanced KRAS-mutant non-small cell lung cancer
PD-L1 expression in primary lung tumor as a superior predictive biomarker to metastatic lymph nodes for first-line immunochemotherapy in advanced KRAS-mutant non-small cell lung cancer Open
View article: Comparative efficacy of UBE simple decompression versus UBE-PLIF in treating degenerative lumbar spondylolisthesis secondary to spinal stenosis: A retrospective study
Comparative efficacy of UBE simple decompression versus UBE-PLIF in treating degenerative lumbar spondylolisthesis secondary to spinal stenosis: A retrospective study Open
The optimal surgical strategy for Meyerding grade I degenerative lumbar spondylolisthesis secondary to spinal stenosis remains controversial. We compared unilateral biportal endoscopic (UBE) simple decompression versus UBE-assisted posteri…
View article: #214 Responsiveness to roxadustat in non-dialysis chronic kidney disease patients with anemia by baseline iron status: a secondary analysis of the ROXSTAR registry
#214 Responsiveness to roxadustat in non-dialysis chronic kidney disease patients with anemia by baseline iron status: a secondary analysis of the ROXSTAR registry Open
Background and Aims The ROXSTAR Registry (ChiCTR2100046322) is a phase 4, multicenter study conducted in China to evaluate the long-term safety and effectiveness of a 52-week roxadustat treatment in both dialysis and non-dialysis (ND) chro…
View article: Comparative analysis of the efficacy of UBE-PLIF versus conventional PLIF in the treatment of L4-5 degenerative spondylolisthesis
Comparative analysis of the efficacy of UBE-PLIF versus conventional PLIF in the treatment of L4-5 degenerative spondylolisthesis Open
Background L4-5 lumbar degenerative spondylolisthesis is a common spinal disease in the middle-aged and elderly population, often accompanied by spinal stenosis and nerve root compression, which seriously affects the quality of life. Tradi…
View article: A Smart Functional Microneedle, Tethered with Neuropeptide S and Tissue Inhibitor of Metalloproteinases, Promotes Skin, Vascular, and Nerve Regeneration for Chronic Diabetic Skin Wound Healing
A Smart Functional Microneedle, Tethered with Neuropeptide S and Tissue Inhibitor of Metalloproteinases, Promotes Skin, Vascular, and Nerve Regeneration for Chronic Diabetic Skin Wound Healing Open
Increased expression and activity of matrix metalloproteinases (MMPs) coupled with reduced neuropeptide secretion at the wound site significantly impair the healing of diabetic skin wounds. Neuropeptides serve as critical neuroregulators i…
View article: Long-term safety and effectiveness of roxadustat in Chinese patients with chronic kidney disease-associated anemia: The ROXSTAR registry
Long-term safety and effectiveness of roxadustat in Chinese patients with chronic kidney disease-associated anemia: The ROXSTAR registry Open
Background: Chronic kidney disease (CKD)-associated anemia (CKD-anemia) is associated with poor survival, and hemoglobin targets are often not achieved with current therapies. Phase 3 trials have demonstrated the treatment efficacy of roxa…
View article: Resistance mechanism of Abies beshanzuensis under heat stress was elucidated through the integration of physiological and transcriptomic analyses
Resistance mechanism of Abies beshanzuensis under heat stress was elucidated through the integration of physiological and transcriptomic analyses Open
Elevated temperatures significantly impaired the normal growth and development of plants. This study combined physiological and transcriptomic analyses to explore the potential mechanisms of response to heat stress in Abies beshanzuensis M…
View article: Characteristics of tongue coating microbiota in diabetic and non-diabetic kidney patients receiving hemodialysis
Characteristics of tongue coating microbiota in diabetic and non-diabetic kidney patients receiving hemodialysis Open
In conclusion, deciphering the tongue coating microbiota of kidney patients undergoing hemodialysis will helpful in assessing the role of oral microbiota in pathobiology and development of kidney disease, which is expected to become a pote…
View article: Correction to: Inside ANEMIA of CKD: Projecting the Future Burden of Anemia of Chronic Kidney Disease and Benefits of Proactive Management: A Microsimulation Model of the Chinese Population
Correction to: Inside ANEMIA of CKD: Projecting the Future Burden of Anemia of Chronic Kidney Disease and Benefits of Proactive Management: A Microsimulation Model of the Chinese Population Open
View article: Inside ANEMIA of CKD: Projecting the Future Burden of Anemia of Chronic Kidney Disease and Benefits of Proactive Management: A Microsimulation Model of the Chinese Population
Inside ANEMIA of CKD: Projecting the Future Burden of Anemia of Chronic Kidney Disease and Benefits of Proactive Management: A Microsimulation Model of the Chinese Population Open
View article: Resistance Mechanism of Abies Beshanzuensis Under Heat Stress Was Elucidated Through the Integration of Physiological and Transcriptomic Analyses
Resistance Mechanism of Abies Beshanzuensis Under Heat Stress Was Elucidated Through the Integration of Physiological and Transcriptomic Analyses Open
View article: Single‐cell landscape analysis reveals systematic senescence in mammalian Down syndrome
Single‐cell landscape analysis reveals systematic senescence in mammalian Down syndrome Open
Background Down syndrome (DS), which is characterized by various malfunctions, is the most common chromosomal disorder. As the DS population continues to grow and most of those with DS live beyond puberty, early‐onset health problems have …
View article: Exosome-Based Regimen Rescues Endometrial Fibrosis in Intrauterine Adhesions Via Targeting Clinical Fibrosis Biomarkers
Exosome-Based Regimen Rescues Endometrial Fibrosis in Intrauterine Adhesions Via Targeting Clinical Fibrosis Biomarkers Open
Intrauterine adhesions (IUA), which is characterized by endometrial fibrosis, continue to be the most common cause of uterine infertility globally. Our work revealed that 3 fibrotic progression markers (Vimentin, COL5A2, and COL1A1) were s…
View article: BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency
BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency Open
View article: Effect of lncRNA MALAT1 on the Granulosa Cell Proliferation and Pregnancy Outcome in Patients With PCOS
Effect of lncRNA MALAT1 on the Granulosa Cell Proliferation and Pregnancy Outcome in Patients With PCOS Open
Follicle arrest is one of the main characteristics of polycystic ovary syndrome (PCOS), the most common endocrinological disorder in reproductive-aged women. Increasing evidence proves that high anti-Mullerian hormone (AMH) levels may play…
View article: Periodic Heat Stress Licenses EMSC Differentiation into Osteoblasts via YAP Signaling Pathway Activation
Periodic Heat Stress Licenses EMSC Differentiation into Osteoblasts via YAP Signaling Pathway Activation Open
Background. The repair and regeneration of large bone defects represent highly challenging tasks in bone tissue engineering. Although recent studies have shown that osteogenesis is stimulated by periodic heat stress, the thermal regulation…
View article: Age-Dependent Metabolomic Profile of the Follicular Fluids From Women Undergoing Assisted Reproductive Technology Treatment
Age-Dependent Metabolomic Profile of the Follicular Fluids From Women Undergoing Assisted Reproductive Technology Treatment Open
Female fertility declines with age, and this natural variation culminates in reproductive senescence. Human follicular fluids are rich in low-molecular weight metabolites which are responsible for the maturation of oocytes. The metabolomic…
View article: A Founder Pathogenic Variant of PPIB Unique to Chinese Population Causes Osteogenesis Imperfecta IX
A Founder Pathogenic Variant of PPIB Unique to Chinese Population Causes Osteogenesis Imperfecta IX Open
Background: Osteogenesis imperfecta (OI) is a heterogeneous genetic disorder characterized by bone fragility. PPIB pathogenic variants cause a perinatal lethal form of OI type IX. A limited number of pathogenic variants have been reported …
View article: Higher Follicular Fluid Progesterone Down-regulated HPGD and COX2 in Granulosa Cells via Suppressing NF-кB Signaling in Endometriosis
Higher Follicular Fluid Progesterone Down-regulated HPGD and COX2 in Granulosa Cells via Suppressing NF-кB Signaling in Endometriosis Open
Background: Luteinized unruptured follicular follicle syndrome (LUFS) is a special type of ovulatory dysfunction and a common cause of infertility. It is estimated that its prevalence is 13% ~ 73% in endometriosis patients. Increasing evid…
View article: Association between abnormal body mass index and pregnancy outcomes in patients following frozen embryo transfer: a systematic review and meta-analysis
Association between abnormal body mass index and pregnancy outcomes in patients following frozen embryo transfer: a systematic review and meta-analysis Open
View article: Periodic Heat Stress Licenses EMSCs Differentiation Into Osteoblasts via YAP Signaling Pathway Activation
Periodic Heat Stress Licenses EMSCs Differentiation Into Osteoblasts via YAP Signaling Pathway Activation Open
BackgroundThe repair and regeneration of large bone defects represent a highly challenging task for bone tissue engineering. Although recent studies have shown that osteogenesis is stimulated by periodic heat stress, the thermal regulation…
View article: Oligo/Amenorrhea Is an Independent Risk Factor Associated With Low Ovarian Response
Oligo/Amenorrhea Is an Independent Risk Factor Associated With Low Ovarian Response Open
Capsule Oligo/amenorrhea is an independent risk factor of low ovarian response but not high ovarian response, particularly in women with low AMH levels. Objective To investigate the association of menstrual cycle length (MCL) with anti-Mül…
View article: Long non-coding RNAs: novel players in the pathogenesis of polycystic ovary syndrome
Long non-coding RNAs: novel players in the pathogenesis of polycystic ovary syndrome Open
Long non-coding RNAs (lncRNAs) are a class of transcripts (>200 nucleotides) lacking protein-coding capacity. Based on the complex three-dimensional structure, lncRNAs are involved in many biological processes and can regulate the expressi…
View article: Vitamin D supplementation prior to in vitro fertilisation in women with polycystic ovary syndrome: a protocol of a multicentre randomised, double-blind, placebo-controlled clinical trial
Vitamin D supplementation prior to in vitro fertilisation in women with polycystic ovary syndrome: a protocol of a multicentre randomised, double-blind, placebo-controlled clinical trial Open
Introduction Polycystic ovary syndrome (PCOS) is one of the leading causes of female infertility, affecting around 5% of women of childbearing age in China. Vitamin D insufficiency is common in women with PCOS and is associated with lower …
View article: The Association Between Previous TORCH Infections and Pregnancy and Neonatal Outcomes in IVF/ICSI-ET: A Retrospective Cohort Study
The Association Between Previous TORCH Infections and Pregnancy and Neonatal Outcomes in IVF/ICSI-ET: A Retrospective Cohort Study Open
Objective: This study aimed to investigate the associations between previous TORCH infection (cytomegalovirus, toxoplasmosis, herpes simplex virus, and rubella) with pregnancy and neonatal outcomes in couples undergoing IVF/ICSI-ET.…
View article: Association of Metformin With Pregnancy Outcomes in Women With Polycystic Ovarian Syndrome Undergoing In Vitro Fertilization
Association of Metformin With Pregnancy Outcomes in Women With Polycystic Ovarian Syndrome Undergoing In Vitro Fertilization Open
In this study, metformin treatment was associated with a decreased risk of OHSS but had no association with the overall clinical pregnancy rate or live birth rate among women with PCOS undergoing IVF/ICSI-ET. Metformin treatment should be …
View article: Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: the first multicentre, phase III trial in China
Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: the first multicentre, phase III trial in China Open
Background and purpose Data on the efficacy and safety of alteplase for acute ischaemic stroke (AIS) administered 3–4.5 hours after the onset of stroke symptoms in Chinese patients is limited. We sought to determine whether AIS patients wo…
View article: A Preliminary Retrospective and Prospective Cohort Study on a Traditional Chinese Long-term Extreme Fasting
A Preliminary Retrospective and Prospective Cohort Study on a Traditional Chinese Long-term Extreme Fasting Open
Background Fasting has long been a ritual or practice in varied religions, and recently, has been noticed to reduce the risk factors of metabolic diseases. In China, varied populations performed a traditional Taoism fasting practice, which…
View article: A Preliminary Retrospective and Prospective Cohort Study on a Traditional Chinese Long-Term Extreme Fasting
A Preliminary Retrospective and Prospective Cohort Study on a Traditional Chinese Long-Term Extreme Fasting Open