Liangyun Guo
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View article: IL-35 Ameliorates Myocardial Strain in Mice with T2DM-Induced Cardiac Injury: Assessment by Layer-Specific Strain
IL-35 Ameliorates Myocardial Strain in Mice with T2DM-Induced Cardiac Injury: Assessment by Layer-Specific Strain Open
IL-35 can enhance myocardial function in diabetic mice. Layer-specific strain could serve as a valuable tool for evaluating interventions in diabetes.
View article: A case description of chronic eosinophilic leukemia with loeffler endocarditis initially characterized by cerebral infarction: the role of 2-dimensional speckle tracking echocardiography in diagnosis
A case description of chronic eosinophilic leukemia with loeffler endocarditis initially characterized by cerebral infarction: the role of 2-dimensional speckle tracking echocardiography in diagnosis Open
View article: The protective effect of sodium-glucose cotransporter-2 inhibitor on left ventricular global longitudinal strain in patients with type 2 diabetes mellitus according to disease duration
The protective effect of sodium-glucose cotransporter-2 inhibitor on left ventricular global longitudinal strain in patients with type 2 diabetes mellitus according to disease duration Open
Our study aimed to elucidate the impact of sodium-glucose cotransporter-2 inhibitor on left ventricular systolic function using global longitudinal strain in type 2 diabetes mellitus patients and to assess its protective effect depending o…
View article: Development and validation of a prediction model of left ventricular systolic dysfunction in type 2 diabetes mellitus
Development and validation of a prediction model of left ventricular systolic dysfunction in type 2 diabetes mellitus Open
This study identified independent risk factors for LVSD in patients with T2DM and developed a predictive nomogram. It allows for clinical decision-making to timely intervene or delay the occurrence of LVSD.
View article: An immune biomarker associated with EMT serves as a predictor for prognosis and drug response in bladder cancer
An immune biomarker associated with EMT serves as a predictor for prognosis and drug response in bladder cancer Open
These results describe dynamic changes in the tumor microenvironment in BLCA and provide evidence for the hypothesis that WDHD1 is a novel biomarker of tumor development. WDHD1 may therefore be a useful target for the detection and managem…
View article: Congenital ureterovaginal fistula: a rare case of single-system ectopic ureter opening into the vagina with ipsilateral ectopic kidney diagnosed via ultrasound
Congenital ureterovaginal fistula: a rare case of single-system ectopic ureter opening into the vagina with ipsilateral ectopic kidney diagnosed via ultrasound Open
View article: Identification of SCAF1, a hub gene affecting VEGF in LIHC, and speculation on its potential therapeutic small molecule based on network pharmacology and transcriptomics
Identification of SCAF1, a hub gene affecting VEGF in LIHC, and speculation on its potential therapeutic small molecule based on network pharmacology and transcriptomics Open
Introduction: Liver hepatocellular carcinoma (LIHC) is a highly vascularized entity closely associated with immune functions, characterized by high incidence, elusive early detection, high malignancy, and poor prognosis. SCAF1 participates…
View article: SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE−/− mice
SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE−/− mice Open
Background Autophagy, as a regulator of cell survival, plays an important role in atherosclerosis (AS). Sperm associated antigen 5 (SPAG5) is closely associated with the classical autophagy pathway, PI3K/Akt/mTOR signaling pathway. This wo…
View article: Identification of SCAF1 as a key factor affecting VEGF in LIHC and its potential target for therapy hypothesized based on network pharmacology and transcriptomics
Identification of SCAF1 as a key factor affecting VEGF in LIHC and its potential target for therapy hypothesized based on network pharmacology and transcriptomics Open
Introduction: Liver hepatocellular carcinoma (LIHC) is a highly vascularized entity closely associated with immune functions, characterized by high incidence, elusive early detection, high malignancy, and poor prognosis. SCAF1 participates…
View article: Prediction of sentinel lymph node metastasis in breast cancer by using deep learning radiomics based on ultrasound images
Prediction of sentinel lymph node metastasis in breast cancer by using deep learning radiomics based on ultrasound images Open
Sentinel lymph node metastasis (SLNM) is a crucial predictor for breast cancer treatment and survival. This study was designed to propose deep learning (DL) models based on grayscale ultrasound, color Doppler flow imaging (CDFI), and elast…
View article: FARSB serves as a novel hypomethylated and immune cell infiltration related prognostic biomarker in hepatocellular carcinoma
FARSB serves as a novel hypomethylated and immune cell infiltration related prognostic biomarker in hepatocellular carcinoma Open
FARSB can serve as a prognostic biomarker for HCC and provide clues about immune infiltration, and m6A modification.
View article: LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway
LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway Open
These data indicate that LGALS2 suppresses PTC progression via PI3K/AKT pathway activation, suggesting that LGALS2 offers value as a treatment target for patients with this cancer type.
View article: Left atrial strain measured by 4D Auto LAQ echocardiography is significantly correlated with high risk of thromboembolism in patients with non-valvular atrial fibrillation
Left atrial strain measured by 4D Auto LAQ echocardiography is significantly correlated with high risk of thromboembolism in patients with non-valvular atrial fibrillation Open
LAS is a useful index for the dynamic evaluation of LA function in patients with non-valvular AF, with higher sensitivity and accuracy than LA volume. LA contraction circumferential strain is an independent high risk factor for thromboembo…
View article: Risk factors of embolism for the cardiac myxoma patients: a systematic review and metanalysis
Risk factors of embolism for the cardiac myxoma patients: a systematic review and metanalysis Open
View article: Long noncoding RNA LINC00115 promotes breast cancer metastasis by inhibiting miR‐7
Long noncoding RNA LINC00115 promotes breast cancer metastasis by inhibiting miR‐7 Open
Breast cancer is the second leading cause of cancer‐related deaths in women. The long noncoding RNA LINC00115 has been reported to be involved in the poor outcome of patients with breast cancer, but the biological function and underlying m…