Bin Liao
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View article: Spatial engineering and d-orbital coupling in axial dual-atom sites for bifunctional oxygen catalysis
Spatial engineering and d-orbital coupling in axial dual-atom sites for bifunctional oxygen catalysis Open
Heterogeneous dual-atom catalysts (DACs) offer great potential to enhance electrocatalytic reaction kinetics and provide diverse active sites. However, achieving precise tuning of metal atom coordination in DACs remains a significant chall…
View article: CD39 and CD73: biological functions, diseases and therapy
CD39 and CD73: biological functions, diseases and therapy Open
Cluster of differentiation 39 (CD39) and CD73 are ectonucleotidases that play pivotal roles in purinergic signaling. CD39 catalyzes the hydrolysis of adenosine triphosphate (ATP) to adenosine diphosphate (ADP) and subsequently to adenosine…
View article: Netlist-Aware Mixed-Cell-Height Legalization
Netlist-Aware Mixed-Cell-Height Legalization Open
Mixed cell heights pose significant challenges to placement in large-scale integrated circuits. In particular, the heterogeneity of cells remarkably complicates the legalization of mixed-cell-height cells. To preserve the global placement …
View article: The Role of WWOX in Cancer Progression: Mechanisms and Therapeutic Potential
The Role of WWOX in Cancer Progression: Mechanisms and Therapeutic Potential Open
Discovered and cloned in 2000, the WW domain-containing oxidoreductase (WWOX) gene serves as a crucial tumor suppressor gene. Its expression is frequently downregulated in a wide spectrum of human malignancies, and this reduction is strong…
View article: A Symmetry-Driven Hybrid Framework Integrating ITTAO and sLSTM-Attention for Air Quality Prediction
A Symmetry-Driven Hybrid Framework Integrating ITTAO and sLSTM-Attention for Air Quality Prediction Open
Air pollution poses a threat to public health, ecosystem stability, and sustainable development. Accurate air quality prediction is essential for environmental protection and achieving sustainability. This study proposes a symmetry-driven …
View article: Disruption of Spore Coat Integrity in Bacillus subtilis Enhances Macrophage Immune Activation
Disruption of Spore Coat Integrity in Bacillus subtilis Enhances Macrophage Immune Activation Open
Probiotics play a pivotal role in animal production by promoting growth, enhancing gut health, and modulating immune responses. Bacillus subtilis, a widely utilized probiotic, forms robust spores that exhibit exceptional resistance, making…
View article: Switching-Type Fluorescence Probe Based on Carbon Dot Nanocomposites for the Visual Detection of Superoxide Anions
Switching-Type Fluorescence Probe Based on Carbon Dot Nanocomposites for the Visual Detection of Superoxide Anions Open
Superoxide anion (O₂⁻), as a crucial member of reactive oxygen species (ROS), plays a pivotal role in cellular function regulation within biological systems and has been extensively implicated in the pathogenesis and progression of numerou…
View article: Tackling the Wildfire Prediction Challenge: An Explainable Artificial Intelligence (XAI) Model Combining Extreme Gradient Boosting (XGBoost) with SHapley Additive exPlanations (SHAP) for Enhanced Interpretability and Accuracy
Tackling the Wildfire Prediction Challenge: An Explainable Artificial Intelligence (XAI) Model Combining Extreme Gradient Boosting (XGBoost) with SHapley Additive exPlanations (SHAP) for Enhanced Interpretability and Accuracy Open
The intensification of global climate change, combined with increasing human activities, has significantly increased wildfire frequency and severity, posing a major global environmental challenge. As an illustration, Guizhou Province in Ch…
View article: Engineering Bipolar Doping in a Janus Dual-Atom Catalyst for Photo-Enhanced Rechargeable Zn-Air Battery
Engineering Bipolar Doping in a Janus Dual-Atom Catalyst for Photo-Enhanced Rechargeable Zn-Air Battery Open
Harnessing solar energy to enhance the rechargeable zinc–air batteries (RZABs) performance is a promising avenue toward sustainable energy storage and conversion. Simultaneously enhancing light-absorption capacity and carrier separation ef…
View article: Takeda G protein–coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases
Takeda G protein–coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases Open
Aging is an independent risk factor for many chronic diseases, including cancer and cardiovascular, pulmonary, and neurodegenerative diseases. In recent years, the mechanisms of aging-related cardiovascular diseases (CVDs) have been studie…
View article: Asymmetrical Triatomic Sites with Long‐Range Electron Coupling for Ultra‐Durable and Extreme‐Low‐Temperature Zinc–Air Batteries
Asymmetrical Triatomic Sites with Long‐Range Electron Coupling for Ultra‐Durable and Extreme‐Low‐Temperature Zinc–Air Batteries Open
Reversible zinc–air battery (ZAB) is a promising alternative for sustainable fuel cells, but the performance is impeded by the sluggish oxygen redox kinetics owing to the suboptimal adsorption and desorption of oxygen intermediates. Here, …
View article: Gallium Electrowinning in Complex Solutions Produced by a Zinc Hydrometallurgy System
Gallium Electrowinning in Complex Solutions Produced by a Zinc Hydrometallurgy System Open
Gallium metal is scattered within Fankou lead-zinc ore, and the existing zinc hydrometallurgy process includes a leaching-extraction-electrowinning sequence to recover the gallium metal. However, impurities from lead-zinc ore have many adv…
View article: Multi-modal transcriptomics: integrating machine learning and convolutional neural networks to identify immune biomarkers in atherosclerosis
Multi-modal transcriptomics: integrating machine learning and convolutional neural networks to identify immune biomarkers in atherosclerosis Open
Background Atherosclerosis, a complex chronic vascular disorder with multifactorial etiology, stands as the primary culprit behind consequential cardiovascular events, imposing a substantial societal and economic burden. Nevertheless, our …
View article: Error analysis of a coaxis five-bar parallel mechanism
Error analysis of a coaxis five-bar parallel mechanism Open
With societal advancement, robots are increasingly being deployed in production processes. Currently, high-precision robots predominantly found in the market are delta parallel robots. Common parallel robots, including delta robots, genera…
View article: The path of integrating the overall national security concept into the network ideological and political education in colleges and universities under the new situation
The path of integrating the overall national security concept into the network ideological and political education in colleges and universities under the new situation Open
In the current complex and changeable international situation, China's national security is facing great challenges and threats, and the importance of the education on holistic approaches to national security in the field of ideology and p…
View article: Robust Direction-of-Arrival Estimation in the Presence of Outliers and Noise Nonuniformity
Robust Direction-of-Arrival Estimation in the Presence of Outliers and Noise Nonuniformity Open
In direction-of-arrival (DOA) estimation with sensor arrays, the background noise is usually modeled to be uncorrelated uniform white noise, such that the related algorithms can be greatly simplified by making use of the property of the no…
View article: Soil keystone viruses are regulators of ecosystem multifunctionality
Soil keystone viruses are regulators of ecosystem multifunctionality Open
Ecosystem multifunctionality reflects the capacity of ecosystems to simultaneously maintain multiple functions which are essential bases for human sustainable development. Whereas viruses are a major component of the soil microbiome that d…
View article: Massive MIMO-ISAC System With 1-Bit ADCs/DACs
Massive MIMO-ISAC System With 1-Bit ADCs/DACs Open
This paper investigates a hardware-efficient massive multiple-input multiple-output integrated sensing and communication (MIMO-ISAC) system with 1-bit analog-to-digital converters (ADCs)/digital-to-analog converters (DACs). The proposed sy…
View article: Resonant-pillar-type acoustic black hole for ultralow-frequency vibration reduction
Resonant-pillar-type acoustic black hole for ultralow-frequency vibration reduction Open
This paper proposes a resonant-type acoustic black hole (ABH). The ABH is achieved with gradient refractive index varies from the center of the lens to its outer surface. The performance of wave focusing and vibration reduction via the ABH…
View article: TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms
TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms Open
The heart and brain are the core organs of the circulation and central nervous system, respectively, and play an important role in maintaining normal physiological functions. Early neuronal and cardiac damage affects organ function. The re…
View article: Protein painting for structural and binding site analysis <i>via</i> intracellular lysine reactivity profiling with <i>o</i> -phthalaldehyde
Protein painting for structural and binding site analysis <i>via</i> intracellular lysine reactivity profiling with <i>o</i> -phthalaldehyde Open
We developed an intracellular chemical covalent labeling method based on lysine reactive shift coupled with a new data analysis strategy RAPID to analyze the intracellular conformational changes of proteins and ligand-binding sites on a pr…
View article: High-throughput drug target discovery using a fully automated proteomics sample preparation platform
High-throughput drug target discovery using a fully automated proteomics sample preparation platform Open
We developed a fully automated proteomics sample preparation platform and a high-throughput drug target discovery workflow, achieving 10 times higher throughput than thermal proteome profiling.
View article: Joint DOA estimation and distorted sensor detection under entangled low-rank and row-sparse constraints
Joint DOA estimation and distorted sensor detection under entangled low-rank and row-sparse constraints Open
The problem of joint direction-of-arrival estimation and distorted sensor detection has received a lot of attention in recent decades. Most state-of-the-art work formulated such a problem via low-rank and row-sparse decomposition, where th…