Linhua Sun
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View article: Single-molecule views of chromatin accessibility and structure during photomorphogenesis
Single-molecule views of chromatin accessibility and structure during photomorphogenesis Open
The dynamic organization of chromatin governs gene expression by regulating DNA accessibility. In plants, light not only initiates photomorphogenesis but also reshapes higher-order chromatin architecture. However, the limited resolution of…
View article: scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer Open
Genomic, epigenomic and transcriptomic alterations are hallmarks of cancer cells, and are closely connected. Especially, epigenetic regulation plays a critical role in tumorigenesis and progression. The growing single-cell epigenome data i…
View article: scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer Open
Genomic, epigenomic, and transcriptomic alterations are hallmarks of cancer cells, and are closely connected. Especially, epigenetic regulation plays a critical role in tumorigenesis and progression. The growing single-cell epigenome data …
View article: Light control of three‐dimensional chromatin organization in soybean
Light control of three‐dimensional chromatin organization in soybean Open
Summary Higher‐order chromatin structure is critical for regulation of gene expression. In plants, light profoundly affects the morphogenesis of emerging seedlings as well as global gene expression to ensure optimal adaptation to environme…
View article: Increased long‐distance and homo‐trans interactions related to H3K27me3 in <i>Arabidopsis</i> hybrids
Increased long‐distance and homo‐trans interactions related to H3K27me3 in <i>Arabidopsis</i> hybrids Open
In plants, the genome structure of hybrids changes compared with their parents, but the effects of these changes in hybrids remain elusive. Comparing reciprocal crosses between Col × C24 and C24 × Col in Arabidopsis using high‐throughput c…
View article: The small nucleolar RNA SnoR28 regulates plant growth and development by directing rRNA maturation
The small nucleolar RNA SnoR28 regulates plant growth and development by directing rRNA maturation Open
Small nucleolar RNAs (snoRNAs) are noncoding RNAs (ncRNAs) that guide chemical modifications of structural RNAs, which are essential for ribosome assembly and function in eukaryotes. Although numerous snoRNAs have been identified in plants…
View article: Chromatin remodeling complexes regulate genome architecture in Arabidopsis
Chromatin remodeling complexes regulate genome architecture in Arabidopsis Open
In eukaryotes, three-dimensional (3D) chromatin architecture maintains genome stability and is important in regulating gene transcription. However, little is known about the mechanisms by which diverse ATP-dependent chromatin remodeling co…
View article: Deciphering the synergistic and redundant roles of CG and non‐CG DNA methylation in plant development and transposable element silencing
Deciphering the synergistic and redundant roles of CG and non‐CG DNA methylation in plant development and transposable element silencing Open
Summary DNA methylation plays key roles in transposable element (TE) silencing and gene expression regulation. DNA methylation occurs at CG, CHG and CHH sequence contexts in plants. However, the synergistic and redundant roles of CG and no…
View article: TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex
TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex Open
Trichomes are specialized epidermal cells that act as barriers against biotic and abiotic stresses. Although the formation of trichomes on hairy organs is well studied, the molecular mechanisms of trichome inhibition on smooth organs are s…
View article: Active DNA demethylation regulates tracheary element differentiation in<i>Arabidopsis</i>
Active DNA demethylation regulates tracheary element differentiation in<i>Arabidopsis</i> Open
A novel role of active DNA demethylation in plant development.
View article: Canonical cytosolic iron-sulfur cluster assembly and non-canonical functions of DRE2 in Arabidopsis
Canonical cytosolic iron-sulfur cluster assembly and non-canonical functions of DRE2 in Arabidopsis Open
As a component of the Cytosolic Iron-sulfur cluster Assembly (CIA) pathway, DRE2 is essential in organisms from yeast to mammals. However, the roles of DRE2 remain incompletely understood largely due to the lack of viable dre2 mutants. In …
View article: Chloroplast Phylogenomic Inference of Green Algae Relationships
Chloroplast Phylogenomic Inference of Green Algae Relationships Open
The green algal phylum Chlorophyta has six diverse classes, but the phylogenetic relationship of the classes within Chlorophyta remains uncertain. In order to better understand the ancient Chlorophyta evolution, we have applied a site patt…
View article: The Origin of Land Plants: A Phylogenomic Perspective
The Origin of Land Plants: A Phylogenomic Perspective Open
Land plants are a natural group, and Charophyte algae are the closest lineages of land plants and have six morphologically diverged groups. The conjugating green algae (Zygnematales) are now suggested to be the extant sister group to land …