Lichao Zhang
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View article: A novel biopsy forceps assisted the removal of a deeply displaced pancreatic duct stent with pancreatic duct stenosis under the guidance of a peroral choledochoscope
A novel biopsy forceps assisted the removal of a deeply displaced pancreatic duct stent with pancreatic duct stenosis under the guidance of a peroral choledochoscope Open
View article: MiR-769-5p of macrophage exosomes induced by GRP78 promotes stemness and chemoresistance in colorectal cancer
MiR-769-5p of macrophage exosomes induced by GRP78 promotes stemness and chemoresistance in colorectal cancer Open
The tumor microenvironment (TME) plays an important role in tumorigenesis and development. Tumor-associated macrophages (TAMs) are essential members of the TME, the exosomes and miRNAs they secrete are crucial in tumor regulation. Our prev…
View article: Deletion of <i>Xist</i> repeat B disrupts cell cycle and asymmetric cell division through <i>Usp9x</i> hyperactivation in mice
Deletion of <i>Xist</i> repeat B disrupts cell cycle and asymmetric cell division through <i>Usp9x</i> hyperactivation in mice Open
During X chromosome inactivation (XCI), Xist RNA establishes silencing by coating the chromosome in cis and binding diverse proteins to promote formation of a heterochromatic domain. However, Xist repeat B role beyond initiation of XCI rem…
View article: A Challenge Selection Approach for Delay-based Physical Unclonable Function on FPGA Utilizing Delay-Balancing Analysis: A Case Study on Arbiter PUF
A Challenge Selection Approach for Delay-based Physical Unclonable Function on FPGA Utilizing Delay-Balancing Analysis: A Case Study on Arbiter PUF Open
View article: Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Low Cells into CD44High Liver Progenitor Cells
Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Low Cells into CD44High Liver Progenitor Cells Open
View article: Functional analysis of TaEMF2 in regulating wheat heading date
Functional analysis of TaEMF2 in regulating wheat heading date Open
View article: A novel wheat S1-bZIP gene, TabZIP11 confers stress resistance in Arabidopsis
A novel wheat S1-bZIP gene, TabZIP11 confers stress resistance in Arabidopsis Open
The majority of basic leucine zipper (bZIP) transcription factor (TF) subgroup S1 play significant regulatory role in response to abiotic stress. However, their functions and underlying molecular mechanisms in abiotic stress responses are …
View article: Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A
Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A Open
View article: SARS-CoV-2 Nsp1 cooperates with initiation factors EIF1 and 1A to selectively enhance translation of viral RNA
SARS-CoV-2 Nsp1 cooperates with initiation factors EIF1 and 1A to selectively enhance translation of viral RNA Open
A better mechanistic understanding of virus-host dependencies can help reveal vulnerabilities and identify opportunities for therapeutic intervention. Of particular interest are essential interactions that enable production of viral protei…
View article: The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3
The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3 Open
The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ transplantation. There are still many enigmas regarding this process and some aspects of the underlyi…
View article: Degradation of Organic Phosphorus Scale Inhibitors Bhmtpmpa and Hdtmpa in Wastewater by Uv/Ps and Uv/H2o2:Degradation Kinetics and Degradation Pathway
Degradation of Organic Phosphorus Scale Inhibitors Bhmtpmpa and Hdtmpa in Wastewater by Uv/Ps and Uv/H2o2:Degradation Kinetics and Degradation Pathway Open
View article: Removal of the Organophosphorus Scale Inhibitor Potassium Hexamethylenediamine Tetramethylphosphonate(Hdtmpa·K6) from Industrial Wastewater Using Uv Oxidation, Flocculation, and the Fenton Reaction
Removal of the Organophosphorus Scale Inhibitor Potassium Hexamethylenediamine Tetramethylphosphonate(Hdtmpa·K6) from Industrial Wastewater Using Uv Oxidation, Flocculation, and the Fenton Reaction Open
View article: Degradation of Organophosphorus Scale Inhibitor Potassium Hexanediamine Tetramethylphosphonate (Hdtmpa·K6) in Wastewater by Uv/Ps, Uv/H2o2: Degradation Kinetics, Degradation Path
Degradation of Organophosphorus Scale Inhibitor Potassium Hexanediamine Tetramethylphosphonate (Hdtmpa·K6) in Wastewater by Uv/Ps, Uv/H2o2: Degradation Kinetics, Degradation Path Open
View article: Exploring the Therapeutic Effects and Mechanisms of Transcranial Alternating Current Stimulation on Improving Walking Ability in Stroke Patients via Modulating Cerebellar Gamma Frequency Band—a Narrative Review
Exploring the Therapeutic Effects and Mechanisms of Transcranial Alternating Current Stimulation on Improving Walking Ability in Stroke Patients via Modulating Cerebellar Gamma Frequency Band—a Narrative Review Open
The cerebellum plays an important role in maintaining balance, posture control, muscle tone, and lower limb coordination in healthy individuals and stroke patients. At the same time, the relationship between cerebellum and motor learning h…
View article: Macrophage-mediated trogocytosis contributes to destroying human schistosomes in a non-susceptible rodent host, Microtus fortis
Macrophage-mediated trogocytosis contributes to destroying human schistosomes in a non-susceptible rodent host, Microtus fortis Open
View article: Unraveling the role of<i>Xist</i>in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A
Unraveling the role of<i>Xist</i>in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A Open
X chromosome inactivation (XCI) is a dosage compensation process that aims to equalize the expression of X-linked genes between males and females. Initiation of XCI relies on Xist , which is continuously expressed in somatic cells during X…
View article: Tumor-associated macrophages confer colorectal cancer 5-fluorouracil resistance by promoting MRP1 membrane translocation via an intercellular CXCL17/CXCL22–CCR4–ATF6–GRP78 axis
Tumor-associated macrophages confer colorectal cancer 5-fluorouracil resistance by promoting MRP1 membrane translocation via an intercellular CXCL17/CXCL22–CCR4–ATF6–GRP78 axis Open
View article: Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial
Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial Open
Background: Although overnight fasting is recommended prior to endoscopic retrograde cholangiopancreatography (ERCP), the benefits and safety of high-carbohydrate fluid diet (CFD) intake 2 h before ERCP remain unclear. This study aimed to …
View article: Comparative Analysis Reveals Different Evolutionary Fates and Biological Functions in Wheat Duplicated Genes (Triticum aestivum L.)
Comparative Analysis Reveals Different Evolutionary Fates and Biological Functions in Wheat Duplicated Genes (Triticum aestivum L.) Open
Wheat (Triticum aestivum L.) is a staple food crop that provides 20% of total human calorie consumption. Gene duplication has been considered to play an important role in evolution by providing new genetic resources. However, the evolution…
View article: SARS-CoV-2 Nsp1 regulates translation start site fidelity to promote infection
SARS-CoV-2 Nsp1 regulates translation start site fidelity to promote infection Open
A better mechanistic understanding of virus-host interactions can help reveal vulnerabilities and identify opportunities for therapeutic interventions. Of particular interest are essential interactions that enable production of viral prote…
View article: GSK3 regulates VRN1 to control flowering time in wheat
GSK3 regulates VRN1 to control flowering time in wheat Open
GLYCOGEN SYNTHASE KINASE 3 physically interacts with VRN1 and regulates its accumulation to mediate flowering in wheat.
View article: LncRNA FALEC increases the proliferation, migration and drug resistance of cholangiocarcinoma through competitive regulation of miR-20a-5p/SHOC2 axis
LncRNA FALEC increases the proliferation, migration and drug resistance of cholangiocarcinoma through competitive regulation of miR-20a-5p/SHOC2 axis Open
In summary, our study revealed that down-regulation of FALEC could inhibit the proliferation, migration, and invasion of CCA cells in vitro by regulating the miR-20a-5p/SHOC2 axis and participating in 5-FU resistance by mediating th…
View article: AV-TranSpeech: Audio-Visual Robust Speech-to-Speech Translation
AV-TranSpeech: Audio-Visual Robust Speech-to-Speech Translation Open
Rongjie Huang, Huadai Liu, Xize Cheng, Yi Ren, Linjun Li, Zhenhui Ye, Jinzheng He, Lichao Zhang, Jinglin Liu, Xiang Yin, Zhou Zhao. Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Pap…
View article: Ferulic Acid and P-Coumaric Acid Synergistically Attenuate Non-Alcoholic Fatty Liver Disease through HDAC1/PPARG-Mediated Free Fatty Acid Uptake
Ferulic Acid and P-Coumaric Acid Synergistically Attenuate Non-Alcoholic Fatty Liver Disease through HDAC1/PPARG-Mediated Free Fatty Acid Uptake Open
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease and has become a growing public health concern worldwide. Polyphenols may improve high-fat diet (HFD)-related NAFLD. Our previous study found that ferulic acid (FA)…
View article: Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation Open
View article: Extracellular vesicles derived from Trichinella Spiralis larvae promote the polarization of macrophages to M2b type and inhibit the activation of fibroblasts
Extracellular vesicles derived from Trichinella Spiralis larvae promote the polarization of macrophages to M2b type and inhibit the activation of fibroblasts Open
Trichinella spiralis ( T. spiralis ) is a globally distributed food-borne parasite that can coexist with the host for a long time after infection. Trichinella -derived secretions can regulate the immune response and fibroblasts of the host…
View article: Massive gastrointestinal haemorrhage caused by pancreatic pseudocyst complicated with Dieulafoy's disease in a child: A case report and review of the literature
Massive gastrointestinal haemorrhage caused by pancreatic pseudocyst complicated with Dieulafoy's disease in a child: A case report and review of the literature Open
Background Pancreatic pseudocyst (PPC) with massive gastrointestinal bleeding is rare, especially in children. Inadvertent intraoperative examination and damage to the gastric mucosa and malformed blood vessels by the fluid content of PPC …
View article: Use of a specialty endoscopy online platform for continuing medical education for clinical endoscopists during the COVID-19 pandemic
Use of a specialty endoscopy online platform for continuing medical education for clinical endoscopists during the COVID-19 pandemic Open
Background To explore the use of a digestive endoscopy professional online platform by domestic endoscopists and its application effect on endoscopists’ continuing medical education, analyse the related problems of continuing medical educa…
View article: <scp>ZSCAN1</scp> Autoantibodies Are Associated with Pediatric Paraneoplastic <scp>ROHHAD</scp>
<span>ZSCAN1</span> Autoantibodies Are Associated with Pediatric Paraneoplastic <span>ROHHAD</span> Open
Objective Rapid‐onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD), is a severe pediatric disorder of uncertain etiology resulting in hypothalamic dysfunction and frequent sudden death. Freque…
View article: Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum Open
Schistosomiasis is an important neglected tropical disease. Interactions between the host immune system and schistosomes are complex. Neutrophils contribute to clearance of large pathogens primarily by releasing neutrophil extracellular tr…