Lícia Maria Henrique da Mota
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View article: Da criação de um Corpus ao treinamento de um grande modelo de linguagem: O que pode dar errado em uma IC?
Da criação de um Corpus ao treinamento de um grande modelo de linguagem: O que pode dar errado em uma IC? Open
Este artigo apresenta a experiência de uma iniciação cient́ıfica voltada ao desenvolvimento de um chatbot especializado em direito do consumidor. Um dos principais desafios enfrentados foi a criação de um conjunto de dados sintético para pe…
View article: Towards a Corpus Methodology for LLMs in the Legal Domain
Towards a Corpus Methodology for LLMs in the Legal Domain Open
The creation of high-quality Question-Answer (QA) datasets is critical for developing reliable legal AI systems, yet a significant gap exists between intrinsic textual metrics and real-world model performance. This paper introduces an end-…
View article: Neuropsychomotor Development of Children Exposed to SARS-CoV-2 in Utero During COVID-19 Pandemic
Neuropsychomotor Development of Children Exposed to SARS-CoV-2 in Utero During COVID-19 Pandemic Open
Introduction: Little is known about the effects of intrauterine exposure to SARS-CoV-2, especially on growth and neurodevelopment in children. Objective: We wished to verify the effect of intrauterine exposure to SARS-CoV-2 on neurological…
View article: Fatores de risco e de proteção para reinfecção por Covid-19: uma revisão integrativa da literatura
Fatores de risco e de proteção para reinfecção por Covid-19: uma revisão integrativa da literatura Open
This study aimed to analyze scientific literature on risk and protective factors for Covid-19 reinfection. An integrative literature review was conducted in five databases [Virtual Health Library (VHL), Embase, Web of Science, Cumulative I…
View article: Avaliação da expressão gênica da via de sinalização da Tirosina Quinase‐2 (TYK2) e da presença do polimorfismo de nucleotídeo único rs12720356 no sangue periférico de pacientes com psoríase grave e perda de resposta ao tratamento sistêmico
Avaliação da expressão gênica da via de sinalização da Tirosina Quinase‐2 (TYK2) e da presença do polimorfismo de nucleotídeo único rs12720356 no sangue periférico de pacientes com psoríase grave e perda de resposta ao tratamento sistêmico Open
View article: Evaluation of Tyrosine Kinase-2 (TYK2) signaling pathway gene expression and the presence of the single-nucleotide polymorphism rs12720356 in the peripheral blood of patients with severe psoriasis and loss of systemic treatment response
Evaluation of Tyrosine Kinase-2 (TYK2) signaling pathway gene expression and the presence of the single-nucleotide polymorphism rs12720356 in the peripheral blood of patients with severe psoriasis and loss of systemic treatment response Open
View article: The dialog between mother and newborn: insights from immune mediator crosstalk elicited by antenatal SARS-COV-2 exposure
The dialog between mother and newborn: insights from immune mediator crosstalk elicited by antenatal SARS-COV-2 exposure Open
Goal The present study intended to evaluate whether the profile of soluble immune mediators observed in cord blood samples resembles the pattern identified for mother serum samples. Methods For this purpose, parallel analysis of chemokines…
View article: Correction: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases
Correction: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases Open
View article: Clinical characteristic and outcomes of pregnant women with COVID‐19: The PROUDEST prospective cohort study
Clinical characteristic and outcomes of pregnant women with COVID‐19: The PROUDEST prospective cohort study Open
The present study intended to characterize the clinical features and outcomes of SARS-CoV-2 infection at distinct pregnancy trimesters. A total of 260 pregnant women with SARS-CoV-2 infection at any pregnancy trimester were enrolled in a p…
View article: PET-Saúde/Equidade: Contribuições das Experiências Compartilhadas para a Formação Acadêmica e Profissional
PET-Saúde/Equidade: Contribuições das Experiências Compartilhadas para a Formação Acadêmica e Profissional Open
Este estudo apresenta um relato de experiência com abordagem qualitativa e reflexiva, realizado no contexto do programa PET-Saúde/Equidade, com o objetivo de relatar as contribuições das trocas de experiências para a formação acadêmica, pr…
View article: Differential Circulating Levels of miR-92a in Patients with SARS-CoV-2 Infection
Differential Circulating Levels of miR-92a in Patients with SARS-CoV-2 Infection Open
Aim: The aim of the present study was to analyze a panel of immune-related miRNAs found in the respiratory tract among patients with symptomatic COVID-19. Method: This is a cross-sectional analysis on the total levels of selected miRNAs as…
View article: COVID-19 IS ASSOCIATED WITH LUPUS FLARE AND PERSISTENT DISEASE ACTIVITY: LONGITUDINAL DATA FROM THE REUMACOV-BRAZIL REGISTER
COVID-19 IS ASSOCIATED WITH LUPUS FLARE AND PERSISTENT DISEASE ACTIVITY: LONGITUDINAL DATA FROM THE REUMACOV-BRAZIL REGISTER Open
PV149 / #422 Poster Topic: AS17 - Miscellaneous Background/Purpose The study aimed to evaluate flares in systemic lupus erythematosus (SLE) patients over a period of 6 months after COVID-19. Methods A multicenter, observational, and prospe…
View article: RESPONSABILIDADE CIVIL DAS INSTITUIÇÕES FINANCEIRAS: ANÁLISE QUANTO ÀS FRAUDES REALIZADAS EM APLICATIVOS BANCÁRIOS APÓS ROUBOS OU FURTOS
RESPONSABILIDADE CIVIL DAS INSTITUIÇÕES FINANCEIRAS: ANÁLISE QUANTO ÀS FRAUDES REALIZADAS EM APLICATIVOS BANCÁRIOS APÓS ROUBOS OU FURTOS Open
O presente artigo analisa a responsabilidade civil das instituições financeiras em casos de fraudes ocorridas em aplicativos bancários após roubos ou furtos de dispositivos móveis. Com o crescimento exponencial do mobile banking no Brasil,…
View article: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases
Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases Open
Background The risk of tuberculosis infection (TBI) and its progression to tuberculosis disease (TBD) among persons with immune-mediated inflammatory diseases (IMID) results from a complex interplay of patient and disease characteristics, …
View article: COVID-19 on patients with immune-mediated rheumatic disease: a comparative study of disease activity, fatigue, and psychological distress over six months
COVID-19 on patients with immune-mediated rheumatic disease: a comparative study of disease activity, fatigue, and psychological distress over six months Open
Objectives To compare the impact of COVID-19 on the clinical status and psychological distress of patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection with that of noninfected IMRD controls during a 6-month…
View article: Comparative Exergetic Assessment for the Modernization of Synthetic Fluids by Natural Refrigerants Used in Residential and Commercial Cooling and Air Conditioning Applications
Comparative Exergetic Assessment for the Modernization of Synthetic Fluids by Natural Refrigerants Used in Residential and Commercial Cooling and Air Conditioning Applications Open
Currently, in the world, there is a real race, involving several manufacturers that search for more efficient refrigerant fluids, with the need to develop new refrigerants to replace the fluids currently being used in air conditioning and …
View article: High-Titer Rheumatoid Factor is Associated with Worse Clinical Outcomes and Higher Needs for Advanced Therapies in Rheumatoid Arthritis Under Real-Life Conditions
High-Titer Rheumatoid Factor is Associated with Worse Clinical Outcomes and Higher Needs for Advanced Therapies in Rheumatoid Arthritis Under Real-Life Conditions Open
View article: Socioeconomic factors and COVID-19 mortality in immune-mediated rheumatic diseases patients: regional analysis from Argentina, Mexico and Brazil
Socioeconomic factors and COVID-19 mortality in immune-mediated rheumatic diseases patients: regional analysis from Argentina, Mexico and Brazil Open
Background SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Europe, and China, wher…
View article: Assessment of the Ru-SATED Questionnaire for Evaluating Sleep Quality in Adults with Severe Asthma Using Biologics
Assessment of the Ru-SATED Questionnaire for Evaluating Sleep Quality in Adults with Severe Asthma Using Biologics Open
View article: Challenges in implementing treat-to-target in rheumatoid arthritis: a perspective from Brazilian rheumatologists
Challenges in implementing treat-to-target in rheumatoid arthritis: a perspective from Brazilian rheumatologists Open
Background Patient management in rheumatoid arthritis (RA) has evolved to a “treat-to-target” (T2T) approach, which entails intensive treatment and regular follow-up with the goal of achieving low levels of disease activity or clinical rem…
View article: Exploring the association of serum prolactin with serum glucose levels and clinical findings in a cohort of patients with early rheumatoid arthritis
Exploring the association of serum prolactin with serum glucose levels and clinical findings in a cohort of patients with early rheumatoid arthritis Open
Background In the context of rheumatoid arthritis and its systemic inflammatory implications, there is an increasing interest in investigating the role of prolactin in the clinical and metabolic aspects of the disease. This study aimed to …
View article: COVID-19 on Patients with Immune-Mediated Rheumatic Disease: A Comparative Study of Disease Activity, Fatigue, and Psychological Distress Over Six Months
COVID-19 on Patients with Immune-Mediated Rheumatic Disease: A Comparative Study of Disease Activity, Fatigue, and Psychological Distress Over Six Months Open
Objectives To compare the impact of COVID-19 on the clinical status and psychological distress of patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection with that of noninfected IMRD controls during a 6-month…
View article: Hydroxychloroquine is associated with lower seroconversion upon 17DD-Yellow fever primovaccination in patients with primary Sjögren’s syndrome
Hydroxychloroquine is associated with lower seroconversion upon 17DD-Yellow fever primovaccination in patients with primary Sjögren’s syndrome Open
The present study aimed at investigating whether the hydroxychloroquine (HCQ) treatment would impact the neutralizing antibody production, viremia levels and the kinetics of serum soluble mediators upon planned 17DD-Yellow Fever (YF) primo…
View article: Predictors of serious infections in rheumatoid arthritis—a prospective Brazilian cohort
Predictors of serious infections in rheumatoid arthritis—a prospective Brazilian cohort Open
Background Infections increase mortality and morbidity and often limit immunosuppressive treatment in rheumatoid arthritis patients. Objective To analyze the occurrence of serious infections and the associated factors in a cohort of rheuma…
View article: COVID-19 Impact on Patients with Immune-Mediated Rheumatic Disease: A Comparative Study of Disease Activity and Psychological Well-Being Over Six Months
COVID-19 Impact on Patients with Immune-Mediated Rheumatic Disease: A Comparative Study of Disease Activity and Psychological Well-Being Over Six Months Open
Objectives To compare the impact of COVID-19 on clinical status and psychological condition in patients with immune-mediated rheumatic diseases (IMRD) infected by SARS-CoV-2 with IMRD controls not infected, during a 6-month follow-up. Meth…
View article: Impact of the COVID-19 Pandemic on People Living with Rheumatoid Arthritis: Experiences and Preferences in Accessing Healthcare Across Five Countries
Impact of the COVID-19 Pandemic on People Living with Rheumatoid Arthritis: Experiences and Preferences in Accessing Healthcare Across Five Countries Open
This survey suggests that the COVID-19 pandemic did negatively impact some aspects of disease management for people living with RA but had positive impacts on the utilization of virtual care. Although participants generally preferred in-pe…
View article: Clinical and genotypic characteristics of patients with Nonaka distal myopathy at a specialized clinic in Salvador, BA
Clinical and genotypic characteristics of patients with Nonaka distal myopathy at a specialized clinic in Salvador, BA Open
Case presentation: Distal myopathy of the Nonaka type is a rare genetic disorder, with an estimated prevalence of 1 in 1,000,000. It is progressive and inherited autosomally recessively, caused by mutations in the GNE gene. This gene encod…
View article: New insights at the interface between leprosy and immune-mediated rheumatic diseases
New insights at the interface between leprosy and immune-mediated rheumatic diseases Open
Leprosy is an infectious and contagious disease of slow evolution, triggered by Mycobacterium leprae . Arthritis is its third most common manifestation, after cutaneous and peripheral nerve involvement. Since musculoskeletal symptoms may b…
View article: Elevated serum IL-6 levels predict treatment interruption in patients with moderate to severe psoriasis: a 6-year real-world cohort study
Elevated serum IL-6 levels predict treatment interruption in patients with moderate to severe psoriasis: a 6-year real-world cohort study Open
View article: Extra-articular manifestations of rheumatoid arthritis remain a major challenge: data from a large, multi-centric cohort
Extra-articular manifestations of rheumatoid arthritis remain a major challenge: data from a large, multi-centric cohort Open
Introduction Although Rheumatoid Arthritis (RA) extra-articular manifestations (ExtRA) occurrence has been decreasing over time, they are still a major mortality risk factor for patients. Objective To determine the prevalence of ExtRA in a…