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View article: POS1347 THE IMMUNOMODULATORY ROLE OF MIF SIGNALING PATHWAY IN MDA5+ DM
POS1347 THE IMMUNOMODULATORY ROLE OF MIF SIGNALING PATHWAY IN MDA5+ DM Open
View article: Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation ― Longitudinal Cohort Study ―
Prognostic Value of Multiple Circulating Biomarkers for Ventricular Arrhythmias in Left Ventricular Hypertrabeculation ― Longitudinal Cohort Study ― Open
Big endothelin-1 concentrations and the location of hypertrabeculation can help with risk stratification for VAs in LVHT.
View article: High Cumulative Non-High-Density Lipoprotein-Cholesterol Concentration Increases the Risk of New-Onset Arterial Stiffness ― A Prospective Cohort Study ―
High Cumulative Non-High-Density Lipoprotein-Cholesterol Concentration Increases the Risk of New-Onset Arterial Stiffness ― A Prospective Cohort Study ― Open
A high cum-non-HDL-C concentration and prolonged exposure to this increase the risk of arterial stiffness. The monitoring and maintenance of appropriate cum-non-HDL-C may reduce the risk of arterial stiffness.
View article: Intracardiac echocardiography-guided transseptal puncture in anteroinferior native septum site for patients undergoing atrial fibrillation ablation with atrial septal closure devices: A case series
Intracardiac echocardiography-guided transseptal puncture in anteroinferior native septum site for patients undergoing atrial fibrillation ablation with atrial septal closure devices: A case series Open
This case series describes the safety and feasibility of an anteroinferior transseptal puncture (TSP) in patients implanted with atrial septal defect (ASD) closure devices for atrial fibrillation (AF) ablation. Eight AF ablation procedures…
View article: T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing
T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing Open
The siIRF1 nanotherapeutic approach shows potential for attenuating myocardial inflammation and mitigating myocarditis progression. Our study highlights the promise of this customized biomimetic nano-delivery system for treating inflammato…
View article: Catheter Ablation for Ventricular Tachycardia in Patients With Biopsy-Proven Myocarditis
Catheter Ablation for Ventricular Tachycardia in Patients With Biopsy-Proven Myocarditis Open
View article: Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019
Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 Open
Background Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. In the context of population aging, a detailed report on the epidemiological trends of NRV…
View article: Comparing simultaneous hybrid ablation with stand-alone thoracoscopic surgical ablation for the treatment of non-paroxysmal atrial fibrillation: a prospective randomized controlled trial
Comparing simultaneous hybrid ablation with stand-alone thoracoscopic surgical ablation for the treatment of non-paroxysmal atrial fibrillation: a prospective randomized controlled trial Open
Aims Advanced atrial fibrillation (AF) is currently a dilemma for electrophysiologists when choosing a minimally invasive treatment strategy. Previous studies have demonstrated the outcome of either catheter ablation or thoracoscopic surgi…
View article: Machine learning for the prediction of 1-year mortality in patients with sepsis-associated acute kidney injury
Machine learning for the prediction of 1-year mortality in patients with sepsis-associated acute kidney injury Open
Introduction Sepsis-associated acute kidney injury (SA-AKI) is strongly associated with poor prognosis. We aimed to build a machine learning (ML)-based clinical model to predict 1-year mortality in patients with SA-AKI. Methods Six ML algo…
View article: T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing
T Lymphocyte-Macrophage Hybrid Membrane-Coated Biomimetic Nanoparticles Alleviate Myocarditis via Suppressing Pyroptosis by Targeting Gene Silencing Open
Utilizing small interfering RNA (siRNA) for gene silencing presents a viable strategy for treating human diseases, including cardiovascular disorders. However, the strategic targeting and delivery of siRNA therapeutics to desired tissues o…
View article: ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular noncompaction: a multicenter longitudinal cohort study
ABLE-SCORE, a simplified risk score for major adverse cardiovascular outcomes in left ventricular noncompaction: a multicenter longitudinal cohort study Open
Background Left ventricular noncompaction (LVNC) is a heterogeneous entity with life-threatening complications and variable prognosis. However, there are limited prediction models available to identify individuals at high risk of adverse o…
View article: Surgical radiofrequency ablation of atrial flutter: which operation should we choose？
Surgical radiofrequency ablation of atrial flutter: which operation should we choose？ Open
The treatment of atrial flutter in patients without structural heart disease by transcatheter radiofrequency ablation of the cavotricuspid isthmus and bilateral pulmonary veins has achieved good results. We report three cases of typical at…
View article: Relationship between stress hyperglycemia ratio and acute kidney injury in patients with congestive heart failure
Relationship between stress hyperglycemia ratio and acute kidney injury in patients with congestive heart failure Open
Background The stress hyperglycemia ratio (SHR) has been demonstrated as an independent risk factor for acute kidney injury (AKI) in certain populations. However, this relationship in patients with congestive heart failure (CHF) remains un…
View article: Effect of short-term cardiac function changes after cardiac resynchronization therapy on long-term prognosis in heart failure patients with and without diabetes
Effect of short-term cardiac function changes after cardiac resynchronization therapy on long-term prognosis in heart failure patients with and without diabetes Open
Background: The relationship between short-term cardiac function changes and long-term outcomes in heart failure (HF) patients undergoing cardiac resynchronization therapy (CRT) remains uncertain, especially when stratified by diabetes sta…
View article: Development and Validation of Machine Learning–Based Models to Predict In-Hospital Mortality in Life-Threatening Ventricular Arrhythmias: Retrospective Cohort Study
Development and Validation of Machine Learning–Based Models to Predict In-Hospital Mortality in Life-Threatening Ventricular Arrhythmias: Retrospective Cohort Study Open
Background Life-threatening ventricular arrhythmias (LTVAs) are main causes of sudden cardiac arrest and are highly associated with an increased risk of mortality. A prediction model that enables early identification of the high-risk indiv…
View article: Atrial fibrillation: mechanism and clinical management
Atrial fibrillation: mechanism and clinical management Open
Atrial fibrillation (AF), the most common sustained arrhythmia, is associated with a range of symptoms, including palpitations, cognitive impairment, systemic embolism, and increased mortality. It places a significant burden on healthcare …
View article: Outcomes of catheter ablation in high-risk patients with Brugada syndrome refusing an implantable cardioverter defibrillator implantation
Outcomes of catheter ablation in high-risk patients with Brugada syndrome refusing an implantable cardioverter defibrillator implantation Open
Aims The aim of this study was to investigate the outcomes of catheter ablation (CA) in preventing arrhythmic events among patients with symptomatic Brugada syndrome (BrS) who declined implantable cardioverter defibrillator (ICD) implantat…
View article: Development and Validation of Machine Learning–Based Models to Predict In-Hospital Mortality in Life-Threatening Ventricular Arrhythmias: Retrospective Cohort Study (Preprint)
Development and Validation of Machine Learning–Based Models to Predict In-Hospital Mortality in Life-Threatening Ventricular Arrhythmias: Retrospective Cohort Study (Preprint) Open
BACKGROUND Life-threatening ventricular arrhythmias (LTVAs) are main causes of sudden cardiac arrest and are highly associated with an increased risk of mortality. A prediction model that enables early identification of the high-risk indi…
View article: Left atrial reservoir strain measurements derived from intracardiac echocardiography in patients with atrial fibrillation: comparison with transthoracic echocardiography
Left atrial reservoir strain measurements derived from intracardiac echocardiography in patients with atrial fibrillation: comparison with transthoracic echocardiography Open
Background Intracardiac echocardiography (ICE) provides accurate left atrial (LA) anatomical information in the procedure of atrial fibrillation (AF) ablation but lacks LA functional assessment. LA reservoir strain (LASr) is an excellent m…
View article: Hybrid Bi-Atrial Ablation Versus Catheter Ablation for Patients with Non-Paroxysmal Atrial Fibrillation and Enlarged Left Atrium
Hybrid Bi-Atrial Ablation Versus Catheter Ablation for Patients with Non-Paroxysmal Atrial Fibrillation and Enlarged Left Atrium Open
View article: Independent and Joint Association of Statin Therapy with Adverse Outcomes in Heart Failure Patients with Atrial Fibrillation Treated with Cardiac Resynchronization Therapy
Independent and Joint Association of Statin Therapy with Adverse Outcomes in Heart Failure Patients with Atrial Fibrillation Treated with Cardiac Resynchronization Therapy Open
AF was associated with poor prognosis, and statin use failed to improve the prognosis. Further analysis showed that statin therapy is ineffective in improving prognosis and fails to attenuate the adverse effects of AF.
View article: Anatomical dilation for the coronary sinus ostium in patients with pulmonary arterial hypertension and its impact to trigger the atrioventricular reentrant tachycardia: a case control study
Anatomical dilation for the coronary sinus ostium in patients with pulmonary arterial hypertension and its impact to trigger the atrioventricular reentrant tachycardia: a case control study Open
Background The incidence of atrioventricular reentrant tachycardia (AVNRT) in pulmonary arterial hypertension (PAH) patients is higher than the general population [1–3]. AVNRT had been reported with larger coronary sinus (CS) ostium in gen…
View article: Diabetes Mellitus Promotes Atrial Structural Remodeling and PARP-1/Ikkα/NF-κB Pathway Activation in Mice
Diabetes Mellitus Promotes Atrial Structural Remodeling and PARP-1/Ikkα/NF-κB Pathway Activation in Mice Open
DM could induce atrial structural remodeling and inflammation in mice.
View article: Trimethylamine N-oxide is associated with coronary atherosclerotic burden in non-ST-segment myocardial infarction patients: SZ-NSTEMI prospective cohort study
Trimethylamine N-oxide is associated with coronary atherosclerotic burden in non-ST-segment myocardial infarction patients: SZ-NSTEMI prospective cohort study Open
Trimethylamine N-oxide (TMAO) is reported to accelerate atherosclerosis and the development of adverse cardiac outcomes. Relationship between coronary atherosclerotic burden and TMAO has been examined in stable coronary artery disease and …
View article: A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score
A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score Open
Objectives . It is important to identify super-responders who can derive most benefits from cardiac resynchronization therapy (CRT). We aimed to establish a scoring model that can be used for predicting super-response to CRT. Methods . We …
View article: Cardiovascular disease during the COVID-19 pandemic: Think ahead, protect hearts, reduce mortality
Cardiovascular disease during the COVID-19 pandemic: Think ahead, protect hearts, reduce mortality Open
Coronavirus disease 2019 (COVID-19) is rapidly spreading globally. As of October 3, 2020, the number of confirmed cases has been nearly 34 million with more than 1 million fatalities. Severe acute respiratory syndrome coronavirus 2 (SARS-C…
View article: Single transseptal puncture technique and contact force catheter: A simplified ablation strategy for paroxysmal atrial fibrillation
Single transseptal puncture technique and contact force catheter: A simplified ablation strategy for paroxysmal atrial fibrillation Open
The present study aimed to evaluate the safety and efficacy of an optimized single transseptal puncture technique and contact force sensing atrial fibrillation (AF) radiofrequency catheter ablation (RFCA) strategy within a clinical setting…
View article: Catheter ablation of nonparoxysmal atrial fibrillation in patients with heart failure with reduced ejection fraction and functional mitral regurgitation
Catheter ablation of nonparoxysmal atrial fibrillation in patients with heart failure with reduced ejection fraction and functional mitral regurgitation Open
Background The optimal treatment for patients with nonparoxysmal atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) has been a subject of debate for years. We aimed to evaluate the efficacy and safety of cath…
View article: Avulsion of coronary sinus after mapping in the great cardiac vein
Avulsion of coronary sinus after mapping in the great cardiac vein Open
View article: Successful case of complex atrial flutter occurring in a patient with congenitally corrected transposition of the great arteries, aberrant left atrial appendage, and situs inversus
Successful case of complex atrial flutter occurring in a patient with congenitally corrected transposition of the great arteries, aberrant left atrial appendage, and situs inversus Open
Background Congenitally corrected transposition of great arteries (ccTGA) is a rare congenital cardiac defect with atrioventricular and ventriculoarterial discordance which leads to heart failure and limits patients’ lifespan. The extremel…