Lijuan Hu
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View article: P02.32.A SINGLE CELL RNA-SEQUENCING OF SUPRAMARGINAL GLIOBLASTOMA RESECTIONS REVEAL THAT THE MESENCHYMAL SIGNATURE IS CONFINED TO THE TUMOR BULK AND IS SHARED ACROSS MALIGNANT AND NON-MALIGNANT CELL TYPES
P02.32.A SINGLE CELL RNA-SEQUENCING OF SUPRAMARGINAL GLIOBLASTOMA RESECTIONS REVEAL THAT THE MESENCHYMAL SIGNATURE IS CONFINED TO THE TUMOR BULK AND IS SHARED ACROSS MALIGNANT AND NON-MALIGNANT CELL TYPES Open
BACKGROUND There are four established tumor cell states in glioblastoma including astrocyte-like, oligodendrocyte precursor cell-like, neural progenitor cell-like, and mesenchymal-like states. Single-cell RNA sequencing has showed that the…
View article: Recurrent single-organ cutaneous small-vessel vasculitis with streptococcal infection in a pediatric patient: A case report
Recurrent single-organ cutaneous small-vessel vasculitis with streptococcal infection in a pediatric patient: A case report Open
Single-organ cutaneous small-vessel vasculitis is a specific type of vasculitis. Its recurrence rate is approximately 10%, and it is a serious health issue that can lead to increased healthcare costs. There have been no reports of successf…
View article: Organotypic Timelapse recording with Transcriptomic Readout (OTTR) links cell behaviour to cell identity in human tissues
Organotypic Timelapse recording with Transcriptomic Readout (OTTR) links cell behaviour to cell identity in human tissues Open
Linking dynamic cellular behaviour to molecular states in intact human tissue remains challenging because during live imaging only limited molecular information can be captured while high-dimensional molecular measurements are destructive.…
View article: Acupuncture for cognitive impairment in type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis protocol
Acupuncture for cognitive impairment in type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis protocol Open
Background The global prevalence of diabetes mellitus (DM) has exceeded 589 million, with the proportion of type 2 diabetes mellitus (T2DM) patients with comorbid cognitive impairment (CI) as high as 49.1%, which has a serious impact on di…
View article: Cell atlas of the developing human meninges reveals a dura origin of meningioma
Cell atlas of the developing human meninges reveals a dura origin of meningioma Open
SUMMARY The vertebrate central nervous system is enveloped by the meninges, consisting of the pia, arachnoid, and dura layers. The arachnoid is hypothesised to give rise to the most common primary intracranial tumours, meningiomas. However…
View article: Late Cretaceous W-Cu-Zn-Pb-Ag mineralization and concealed monzogranite in the Wutong deposit, eastern Guangxi, South China
Late Cretaceous W-Cu-Zn-Pb-Ag mineralization and concealed monzogranite in the Wutong deposit, eastern Guangxi, South China Open
View article: Clinical Application of the High Superficial Musculoaponeurotic System for Facial Rejuvenation in Chinese Patients
Clinical Application of the High Superficial Musculoaponeurotic System for Facial Rejuvenation in Chinese Patients Open
Background: Face lift surgery can improve facial sagging and reestablish a youthful relationship between the soft tissues and the underlying skeleton. The early manifestations of aging in the periorbital region include sagging of the later…
View article: High-coherence fluxonium qubits manufactured with a wafer-scale-uniformity process
High-coherence fluxonium qubits manufactured with a wafer-scale-uniformity process Open
Fluxonium qubits are recognized for their high coherence times and high operation fidelities. These are attributed to their unique design incorporating a superinductor, which is typically implemented using an array of over 100 Josephson ju…
View article: Language in Culture: Lectures on the Social Semiotics of Language, by Michael Silverstein, edited by E. Summerson Carr, Susan Gal, and Constantine V. Nakassis and Language Debates: Theory and Reality in Language Learning, Teaching and Research, edited by Ana de Medeiros and Debra Kelly
Language in Culture: Lectures on the Social Semiotics of Language, by Michael Silverstein, edited by E. Summerson Carr, Susan Gal, and Constantine V. Nakassis and Language Debates: Theory and Reality in Language Learning, Teaching and Research, edited by Ana de Medeiros and Debra Kelly Open
View article: Tuning thermal conductivity of thermal barrier ceramic SrZrO3 via La doping: computational study using machine learning potential
Tuning thermal conductivity of thermal barrier ceramic SrZrO3 via La doping: computational study using machine learning potential Open
View article: Development and challenges of autonomous electric vertical take-off and landing aircraft
Development and challenges of autonomous electric vertical take-off and landing aircraft Open
Urban Air Transportation (UAT) encompasses private aircraft, air taxis, and specialized missions. These missions include aerial sightseeing, logistics transportation, emergency response, and anti-terrorism operations. They impose stringent…
View article: Temporal Incision Super-high Superficial Musculoaponeurotic System Face Lift for Chinese Patients
Temporal Incision Super-high Superficial Musculoaponeurotic System Face Lift for Chinese Patients Open
Background: This investigation assessed patient satisfaction with a temporal incision technique using a super-high superficial musculoaponeurotic system (SMAS) flap for midface lifting in a Chinese patient cohort. Methods: From July 2019 t…
View article: GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant Open
Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are lethal brain tumors lacking targeted therapies. They originate from interneuronal precursors; however, leveraging this origin for therapeutic insights remains unexplored. Here, …
View article: Study on the evaluation method of pilot workload in eVTOL aircraft operation
Study on the evaluation method of pilot workload in eVTOL aircraft operation Open
This paper investigates the pilot control strategy and workload associated with the manned electric Vertical Take-Off and Landing (eVTOL) aircraft. This research aims to identify control strategies that are both rational and effective in r…
View article: Land use shapes the microbial community structure by altering soil aggregates and dissolved organic matter components
Land use shapes the microbial community structure by altering soil aggregates and dissolved organic matter components Open
The agro-pastoral ecotone epitomizes the ecologically fragile semi-arid zone, where the soil microbiomes play a pivotal role in regulating its multifunctionality. However, whether and how changes in soil structure and organic matter compos…
View article: Distributed photovoltaic hosting capacity assessment technology considering stable operation of distribution network
Distributed photovoltaic hosting capacity assessment technology considering stable operation of distribution network Open
The rise of distributed photovoltaic (PV) in recent years has enhanced the sustainability, reliability, and flexibility of power systems. However, excessive PV access beyond the distribution network’s hosting capacity can jeopardize grid s…
View article: High coherence fluxonium manufactured with a wafer-scale uniformity process
High coherence fluxonium manufactured with a wafer-scale uniformity process Open
Fluxonium qubits are recognized for their high coherence times and high operation fidelities, attributed to their unique design incorporating a superinductor, which is typically implemented using an array of over 100 Josephson junctions. H…
View article: Chromatin accessibility during human first-trimester neurodevelopment
Chromatin accessibility during human first-trimester neurodevelopment Open
View article: Diagnostic accuracy of magnetically guided capsule endoscopy with a detachable string for detecting oesophagogastric varices in adults with cirrhosis: prospective multicentre study
Diagnostic accuracy of magnetically guided capsule endoscopy with a detachable string for detecting oesophagogastric varices in adults with cirrhosis: prospective multicentre study Open
Objective To evaluate the diagnostic accuracy and safety of using magnetically guided capsule endoscopy with a detachable string (ds-MCE) for detecting and grading oesophagogastric varices in adults with cirrhosis. Design Prospective multi…
View article: High lipoprotein(a) concentration is associated with moyamoya disease
High lipoprotein(a) concentration is associated with moyamoya disease Open
Background Moyamoya disease (MMD) has attracted the attention of scholars because of its rarity and unknown etiology. Methods Data for this study were sourced from the Second Affiliated Hospital of Nanchang University. Regression analyses …
View article: Evaluation of urinary neutrophil gelatinase associated lipocalin in the early diagnosis of acute kidney injury with sepsis
Evaluation of urinary neutrophil gelatinase associated lipocalin in the early diagnosis of acute kidney injury with sepsis Open
uNGAL is superior to Scr for early diagnosis of AKI patients with sepsis.
View article: WHOLE BRAIN SINGLE NUCLEUS TRANSCRIPTOMICS IN HUMAN: WHAT WE KNOW SO FAR
WHOLE BRAIN SINGLE NUCLEUS TRANSCRIPTOMICS IN HUMAN: WHAT WE KNOW SO FAR Open
Although single-cell RNA sequencing has revolutionized our understanding of the mammalian brain, the diversity of cell types that contribute to the human brain remains poorly understood. We therefore used high-throughput single-nucleus RNA…
View article: Applications of machine learning in familial hypercholesterolemia
Applications of machine learning in familial hypercholesterolemia Open
Familial hypercholesterolemia (FH) is a common hereditary cholesterol metabolic disease that usually leads to an increase in the level of low-density lipoprotein cholesterol in plasma and an increase in the risk of cardiovascular disease. …
View article: Native approach to controlled-Z gates in inductively coupled fluxonium qubits
Native approach to controlled-Z gates in inductively coupled fluxonium qubits Open
The fluxonium qubits have emerged as a promising platform for gate-based quantum information processing. However, their extraordinary protection against charge fluctuations comes at a cost: when coupled capacitively, the qubit-qubit intera…
View article: A predictive model for identifying secondary underlying diseases of hemophagocytic lymphohistiocytosis
A predictive model for identifying secondary underlying diseases of hemophagocytic lymphohistiocytosis Open
Background Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disease of immune hyperactivation that arises in the context of infectious, inflammatory, or neoplastic triggers. The aim of this study was to establ…
View article: Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin
Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin Open
View article: The comparison between young and old patients and the prognostic roles of magnetic resonance imaging-related parameter characteristics in young patients—a retrospective cohort study
The comparison between young and old patients and the prognostic roles of magnetic resonance imaging-related parameter characteristics in young patients—a retrospective cohort study Open
The present study provides a reference for further evaluation of the characteristics of young breast cancer patients.
View article: Supplemental Table 2 from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma
Supplemental Table 2 from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma Open
Cell Line authentication
View article: supplemental figure legend from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma
supplemental figure legend from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma Open
supplemental figure legend
View article: Supplemental Methods and Materials from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma
Supplemental Methods and Materials from The <i>RARS–MAD1L1</i> Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma Open
Supplemental Methods and Materials