Lijun Zhang
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View article: Efficacy and safety of orthokeratology sequentially combined with escalating atropine concentrations for myopia control in children
Efficacy and safety of orthokeratology sequentially combined with escalating atropine concentrations for myopia control in children Open
View article: Spatiotemporal trend of sensory impairments in China and its provinces from 2011 to 2018: insights from CHARLS
Spatiotemporal trend of sensory impairments in China and its provinces from 2011 to 2018: insights from CHARLS Open
View article: Imaging findings and clinical analysis of cardiac hemangioma
Imaging findings and clinical analysis of cardiac hemangioma Open
Background Cardiac hemangioma, a rare benign tumor representing ~5% of benign cardiac tumors, often lacks specific symptoms. Echocardiography is key for screening/diagnosis, enabling precise tumor localization and morphological evaluation.…
View article: Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from Multi-national Prospective Cohorts
Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from Multi-national Prospective Cohorts Open
View article: Role and molecular mechanisms of hypoxia‑derived exosomal miR‑301a on gemcitabine resistance in pancreatic cancer
Role and molecular mechanisms of hypoxia‑derived exosomal miR‑301a on gemcitabine resistance in pancreatic cancer Open
Pancreatic cancer is a highly aggressive digestive malignancy and gemcitabine (GEM)-based chemotherapy remains a cornerstone of its treatment despite widespread resistance. The present study employed human pancreatic cancer cell lines to c…
View article: Genetic analysis of an asymptomatic female with a large Xp deletion revealed insights into the X chromosome inactivation pattern: a case report
Genetic analysis of an asymptomatic female with a large Xp deletion revealed insights into the X chromosome inactivation pattern: a case report Open
View article: Marrying Perona Malik diffusion with Mamba for efficient pediatric echocardiographic left ventricular segmentation
Marrying Perona Malik diffusion with Mamba for efficient pediatric echocardiographic left ventricular segmentation Open
Segmenting echocardiographic images is a crucial step in assessing heart function, as clinical indicators can be obtained by precisely delineating the left ventricle. The success of subsequent heart analyses depends entirely on the precisi…
View article: Genome-wide identification and characterization of the Brassinazole-resistant gene family and associated responses to osmotic stress in Avena sativa
Genome-wide identification and characterization of the Brassinazole-resistant gene family and associated responses to osmotic stress in Avena sativa Open
Background The Brassinazole-resistant (BZR) family of transcription factors acts as key regulators in brassinosteroid (BR) signaling, influencing plant growth, development, biotic and abiotic stresses. However, systematic analysis of the B…
View article: Fixation for metaphyseal-diaphyseal junction noncomminuted fracture of the distal humerus in children: K-wire or ESIN, how to decide?
Fixation for metaphyseal-diaphyseal junction noncomminuted fracture of the distal humerus in children: K-wire or ESIN, how to decide? Open
Background The metaphyseal-diaphyseal junction (MDJ) fracture of the distal humerus has posed significant difficulty clinically, as the increased height of the distal fragmant makes it hard for Kirschner wires to reach the proximal fragmen…
View article: Genomic insights into the divergence between hulled and hulless oats
Genomic insights into the divergence between hulled and hulless oats Open
Common oat, one of the most important crops worldwide, comprises hulled and hulless types with substantial agronomic differences. However, their evolutionary history and the genomic basis of phenotypic variations remain unclear. Herein, we…
View article: Effect of intraoperative mitomycin C application at different concentrations on corneal densitometry after SmartSurfACE transepithelial photorefractive keratectomy
Effect of intraoperative mitomycin C application at different concentrations on corneal densitometry after SmartSurfACE transepithelial photorefractive keratectomy Open
PURPOSE: This study aimed to investigate corneal densitometry (CD), visual, and refractive outcomes after transepithelial photorefractive keratectomy (TPRK) using smart pulse technology (SPT), known as the SmartSurface procedure, in patien…
View article: Author Correction: The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid
Author Correction: The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid Open
View article: Prediction model for severe mycoplasma pneumoniae pneumonia and analysis of macrolide-resistance in children: a case-control study
Prediction model for severe mycoplasma pneumoniae pneumonia and analysis of macrolide-resistance in children: a case-control study Open
We developed and validated a nomogram for quantitative risk assessment of SMPP. This model can aid clinicians in the early identification of severe cases and in optimizing treatment strategies.
View article: Prevalence of and risk factors for adolescent scoliosis from a multi-year school screening programme in Eastern China
Prevalence of and risk factors for adolescent scoliosis from a multi-year school screening programme in Eastern China Open
Objective This study aimed to determine the occurrence of adolescent scoliosis (AS) and identify possible associated factors in Eastern China. Methods The screening technique involved performing forward bending tests and using scoliometer …
View article: Cardiac magnetic resonance follow-up of myocardial function in patients with chronic total occlusion of the coronary arteries: a retrospective cohort study
Cardiac magnetic resonance follow-up of myocardial function in patients with chronic total occlusion of the coronary arteries: a retrospective cohort study Open
Baseline LVEF and myocardial viability assessed via quantitative CMR imaging before CTO-PCI may help select patients who will benefit from the procedure. Although overall LVEF did not improve following CTO-PCI, patients with baseline LVEF …
View article: Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease
Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease Open
Gut microbiota exerts a pivotal influence on the development of Metabolic Associated Fatty Liver Disease (MAFLD), although the specific contributions of individual bacterial strains and their metabolites remain poorly defined. We conducted…
View article: Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon
Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon Open
Microbial adaptations to resource availability are crucial to predict the responses of ecosystems to carbon (C) changes, yet viral roles in C cycling under varying levels of C remain elusive. Through metagenomic analysis of soils with cont…
View article: Prediction Model for Severe Mycoplasma pneumoniae Pneumonia and Analysis of Macrolide-resistance in Children: A case-control Study
Prediction Model for Severe Mycoplasma pneumoniae Pneumonia and Analysis of Macrolide-resistance in Children: A case-control Study Open
Background To analyze the clinical features, laboratory findings, and imaging characteristics of severe Mycoplasma pneumoniae pneumonia (SMPP) in children, identify early warning indicators, and characterize macrolide-resistant M. pneumoni…
View article: Knowledge mapping of posterior capsular opacification from 2011 to 2023: A bibliometric analysis
Knowledge mapping of posterior capsular opacification from 2011 to 2023: A bibliometric analysis Open
This bibliometric analysis explores the current status and trends of global research on posterior capsular opacification (PCO). A search of the Web of Science Core Collection (WoSCC) database was conducted to identify publications on PCO f…
View article: Atmospheric Pollutants, Cardiometabolic Disorders, and Dementia in Trajectory Analysis: A 13‐Year Longitudinal Cohort Study
Atmospheric Pollutants, Cardiometabolic Disorders, and Dementia in Trajectory Analysis: A 13‐Year Longitudinal Cohort Study Open
Background First cardiometabolic disorders (FCMDs) and dementia pose a significant burden on aging populations. Investigating the association between atmospheric pollutants and the progression of FCMDs and dementia is crucial. Methods A pr…
View article: Plasma proteomic profiles in diverse populations identify biomarkers predicting metabolic dysfunction-associated steatotic liver disease up to 16 years before onset
Plasma proteomic profiles in diverse populations identify biomarkers predicting metabolic dysfunction-associated steatotic liver disease up to 16 years before onset Open
Early identification of metabolic dysfunction-associated steatotic liver disease (MASLD) is crucial for preventing disease progression, yet reliable predictive tools remain lacking. We analyzed proteomics data of 37,966 participants withou…
View article: Plasma‐Derived Exosomal <scp>i‐tRF‐LeuCAA</scp> as Biomarker for Glioma Diagnosis and Promoter of Epithelial‐Mesenchymal Transition via <scp>TPM4</scp> Regulation
Plasma‐Derived Exosomal <span>i‐tRF‐LeuCAA</span> as Biomarker for Glioma Diagnosis and Promoter of Epithelial‐Mesenchymal Transition via <span>TPM4</span> Regulation Open
Aims This study aimed to discover plasma‐derived exosomal tsRNAs that serve as novel diagnostic biomarkers for glioma and to investigate the mechanism by which tsRNAs regulate glioma development. Methods Differentially expressed tsRNAs in …
View article: Analysis of Lifestyle and Genetic Risk Factors in Urban Women in China Who Had Malignant or Suspected Malignant Breast Nodules Identified via Breast Cancer Screening
Analysis of Lifestyle and Genetic Risk Factors in Urban Women in China Who Had Malignant or Suspected Malignant Breast Nodules Identified via Breast Cancer Screening Open
Objective: Breast cancer seriously endangers women’s health. It is very important to analyze the lifestyle and genetic risk factors for people with malignant or suspected malignant nodules in breast cancer screening for the prevention of b…
View article: Management of delayed corneal epithelial healing after refractive surgery: five case reports
Management of delayed corneal epithelial healing after refractive surgery: five case reports Open
Background Transepithelial photorefractive keratectomy using Smart Pulse Technology (SPT-TransPRK) is currently the leading method for superficial refractive surgery, offering advantages such as a non-contact procedure, shorter operation t…
View article: Improved evaluation of coronary artery diseases from patients with coronary calcification utilizing FFRCT: a comparative study against CCTA
Improved evaluation of coronary artery diseases from patients with coronary calcification utilizing FFRCT: a comparative study against CCTA Open
FFRCT offers superior diagnostic accuracy over CCTA, particularly in patients with moderate to severe calcification. Furthermore, the LASSO model enhances diagnostic performance in these cases, demonstrating potential for improv…
View article: PVBF: A Framework for Mitigating Parameter Variation Imbalance in Online Continual Learning
PVBF: A Framework for Mitigating Parameter Variation Imbalance in Online Continual Learning Open
Online continual learning (OCL), which enables AI systems to adaptively learn from non-stationary data streams, is commonly achieved using experience replay (ER)-based methods that retain knowledge by replaying stored past during training.…
View article: Melatonin antagonizes bone loss induced by mechanical unloading via IGF2BP1-dependent m6A regulation
Melatonin antagonizes bone loss induced by mechanical unloading via IGF2BP1-dependent m6A regulation Open
Disuse bone loss is prone to occur in individuals who lack mechanical stimulation due to prolonged spaceflight or extended bed rest, rendering them susceptible to fractures and placing an enormous burden on social care; nevertheless, the u…
View article: Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from UK Biobank and All of Us Cohorts
Accelerated biological aging, inflammatory bowel disease, genetic susceptibility and life expectancy: Evidence from UK Biobank and All of Us Cohorts Open
Background: Inflammatory bowel disease (IBD) is a chronic condition affecting individuals across all age groups. However, the association between IBD and biological aging remains unclear. Methods: We utilized data from the UK Biobank and t…
View article: Targeting farnesoid X receptor as aging intervention therapy
Targeting farnesoid X receptor as aging intervention therapy Open
View article: Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023
Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023 Open
Background The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region. Methods The clinical records of 359 patients (394 eyes) who underwen…