Liang Wang
YOU?
Author Swipe
View article: Lysine restriction attenuates obesity-related anxiety-like behaviors via increasing Oscillibacter ruminantium-mediated tryptophol regulation
Lysine restriction attenuates obesity-related anxiety-like behaviors via increasing Oscillibacter ruminantium-mediated tryptophol regulation Open
LRD attenuates obesity-associated anxiety-like behaviors by enriching Oscillibacter ruminantium and modulating tryptophol production, thereby activating the FTO-IGF2BP1-LGR6 signaling axis. These findings would indicate LRD as a microbiota…
View article: Autism-Associated Gut Microbiota–Derived Enterococcus facium Modulates Gut–Brain Axis Function and Behavior in Mice
Autism-Associated Gut Microbiota–Derived Enterococcus facium Modulates Gut–Brain Axis Function and Behavior in Mice Open
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by social communication deficits, repetitive behaviors, and restricted interests. Although its pathogenesis is not fully understood, emerging evidence s…
View article: A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid
A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid Open
View article: Prognostic Value of a Novel Staging System Integrating Lymph Node Station Number and Tumor Regression Grade for Esophageal Cancer Following Neoadjuvant Chemoradiotherapy
Prognostic Value of a Novel Staging System Integrating Lymph Node Station Number and Tumor Regression Grade for Esophageal Cancer Following Neoadjuvant Chemoradiotherapy Open
Background The aim of this study was to evaluate the prognostic value of tumor regression grade (TRG) in patients with esophageal cancer after neoadjuvant therapy and to validate the prognostic value of a novel TRG system (nTRG) system inc…
View article: Maternal 25-Hydroxycholecalciferol Supplementation Dynamically Altered Milk Fatty Acid and Amino Acid Profiles and Improves Sow Performance
Maternal 25-Hydroxycholecalciferol Supplementation Dynamically Altered Milk Fatty Acid and Amino Acid Profiles and Improves Sow Performance Open
This study was performed to evaluate the effects of maternal 25-hydroxycholecalciferol (25-OH-D3) supplementation on sow performance, as well as the dynamic alterations of both the amino acid and fatty acid profiles in milk. On day 85 of g…
View article: The hidden costs of automation: does robot adoption affect children’s mental health?
The hidden costs of automation: does robot adoption affect children’s mental health? Open
Introduction Industrial automation is profoundly transforming the labor market, yet it may also impose hidden costs beyond economic outcomes. In particular, heightened labor market competition caused by robot adoption may create intergener…
View article: Associations of phenols, parabens, and phthalate compounds related to personal care products with osteoarthritis: evidence from population-based and network toxicology studies
Associations of phenols, parabens, and phthalate compounds related to personal care products with osteoarthritis: evidence from population-based and network toxicology studies Open
Osteoarthritis (OA) is a prevalent chronic musculoskeletal disease leading to significant disability worldwide, exacerbated by environmental factors and exposure to personal care products (PCPs). This study investigated the associations be…
View article: Gipc3 Mutation Might Cause Sensorineural Hearing Loss by Inhibiting Mitophagy in Inner Ear Hair Cells
Gipc3 Mutation Might Cause Sensorineural Hearing Loss by Inhibiting Mitophagy in Inner Ear Hair Cells Open
View article: Effect of Marine‐Derived Scallop Peptide Hydrolysate on Immune Modulation and Gut Microbiota Restoration in Cyclophosphamide‐Induced Immunosuppressed Mice
Effect of Marine‐Derived Scallop Peptide Hydrolysate on Immune Modulation and Gut Microbiota Restoration in Cyclophosphamide‐Induced Immunosuppressed Mice Open
Cyclophosphamide (CTX), a chemotherapy agent, can weaken immune responses and disrupt gut microbiota, resulting in dysbiosis and inflammation. The gut microbiota, a composite community of microorganisms, plays a central role in regulating …
View article: Circulatory prostate cancer proteome landscapes and prognostic biomarkers in metastatic castrate resistant prostate cancer
Circulatory prostate cancer proteome landscapes and prognostic biomarkers in metastatic castrate resistant prostate cancer Open
Plasma proteome profiling can identify novel circulatory DEPs associated with mCRPC state survivals. Overexpression of RRM2 is linked to poor mCRPC survival and its inclusion alongside conventional prognostic factors enhances the predictiv…
View article: The Kratos Framework for Heterogeneous Astrophysical Simulations: Ray Tracing, Reacting Flow and Thermochemistry
The Kratos Framework for Heterogeneous Astrophysical Simulations: Ray Tracing, Reacting Flow and Thermochemistry Open
Thermochemistry, ray-tracing radiation, and radiation-matter interactions are important processes which are computationally difficult to model in astrophysical simulations, addressed by introducing novel algorithms optimized for heterogene…
View article: Human neural stem cell-derived exosomes activate PINK1/Parkin pathway to protect against oxidative stress-induced neuronal injury in ischemic stroke
Human neural stem cell-derived exosomes activate PINK1/Parkin pathway to protect against oxidative stress-induced neuronal injury in ischemic stroke Open
These findings suggest that hNSC-Exos alleviate OS-induced neuronal damage by regulating the PINK1/Parkin pathway. These reveals a novel role of stem cell-derived mitochondrial therapy in promoting neuroprotection and suggest their potenti…
View article: Metalized Porphyrin‐Based COFs for Conductive Porous Layers in Perovskite Solar Cells to Enhance Electron Injection, Defect Passivation, and Lead‐Protection
Metalized Porphyrin‐Based COFs for Conductive Porous Layers in Perovskite Solar Cells to Enhance Electron Injection, Defect Passivation, and Lead‐Protection Open
In perovskite solar cells (PSCs), the introduction of an intermediate layer to bridge the transport and photoactive layers has become a key strategy for enhancing carrier extraction efficiency. However, traditional approaches are often lim…
View article: Umbilical mesenchymal stem cells mitigate T-cell compartments shift and Th17/Treg imbalance in acute ischemic stroke via mitochondrial transfer
Umbilical mesenchymal stem cells mitigate T-cell compartments shift and Th17/Treg imbalance in acute ischemic stroke via mitochondrial transfer Open
View article: CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling Open
CD146 plays a key role in cancer progression and metastasis. Cancer stem cells (CSCs) are responsible for tumor initiation, drug resistance, metastasis, and recurrence. In this study, we explored the role of CD146 in the regulation of live…
View article: The effects of flight training on flying cadets’ brain structure
The effects of flight training on flying cadets’ brain structure Open
In recent years, the impact of professional training on brain structure has sparked extensive research interest. Research into pilots as a high-demand, high-load, and high-cost occupation holds significant academic and economic value. The …
View article: Human Genome Book: Words, Sentences and Paragraphs
Human Genome Book: Words, Sentences and Paragraphs Open
Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…
View article: Study on Fermentation Preparation, Stability, and Angiotensin-Converting Enzyme Inhibitory Activity of Tomato Pomace Peptide
Study on Fermentation Preparation, Stability, and Angiotensin-Converting Enzyme Inhibitory Activity of Tomato Pomace Peptide Open
The substantial quantity of discarded tomato pomace (TP) results in the waste of valuable resources. This study utilizes these tomato by-products by mixing them with water in a specific proportion and fermenting the mixture in two stages: …
View article: Establishment of a high-throughput scale-down clone screening platform for intensified fed-batch culture of CHO cells
Establishment of a high-throughput scale-down clone screening platform for intensified fed-batch culture of CHO cells Open
Purpose To develop a scale-down clone screening platform for the intensified fed-batch (IFB) process to allow efficient identification of high expressing clones fitting the IFB culture strategy in bioreactor. Results Three monoclonal antib…
View article: DNAHLM - DNA sequence and Human Language mixed large language Model
DNAHLM - DNA sequence and Human Language mixed large language Model Open
There are already many DNA large language models, but most of them still follow traditional uses, such as extracting sequence features for classification tasks. More innovative applications of large language models, such as prompt engineer…
View article: Sea conch (<i>Rapana venosa</i>) peptide hydrolysate regulates <scp>NF</scp>‐<scp>κB</scp> pathway and restores intestinal immune homeostasis in <scp>DSS</scp>‐induced colitis mice
Sea conch (<i>Rapana venosa</i>) peptide hydrolysate regulates <span>NF</span>‐<span>κB</span> pathway and restores intestinal immune homeostasis in <span>DSS</span>‐induced colitis mice Open
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract. Sea conch peptide hydrolysate (CPH) was produced by enzymatic digestion of fresh conch meat with trypsin enzyme. To analyze the molecular c…
View article: NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice Open
View article: Human neural stem cell-derived artificial organelles to improve oxidative phosphorylation
Human neural stem cell-derived artificial organelles to improve oxidative phosphorylation Open
View article: Human neural stem cell–derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway
Human neural stem cell–derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway Open
JOURNAL/nrgr/04.03/01300535-202511000-00028/figure1/v/2025-09-25T165316Z/r/image-tiff Human neural stem cell–derived extracellular vesicles exhibit analogous functions to their parental cells, and can thus be used as substitutes for stem c…
View article: Polysaccharides derived from Deglet Noor dates modulate amoxicillin-induced dysbiosis and enhance intestinal barrier function
Polysaccharides derived from Deglet Noor dates modulate amoxicillin-induced dysbiosis and enhance intestinal barrier function Open
Despite their well-known nutritional importance, the consumption of dates is linked to several health benefits. This study investigates the potential of Deglet Noor polysaccharides (DP) in reverting gut dysbiosis. The study aimed to charac…
View article: A Multi-Type Dynamic Response Control Strategy for Energy Consumption
A Multi-Type Dynamic Response Control Strategy for Energy Consumption Open
In the context of the “Dual-Carbon Strategy”, the seamless integration and optimal utilization of renewable energy sources present a pressing challenge for the emerging power system. The advent of demand-side response technology offers a p…
View article: Gipc3 Mutation Might Cause Sensorineural Hearing Loss by Inhibiting Mitophagy in Inner Ear Hair Cells
Gipc3 Mutation Might Cause Sensorineural Hearing Loss by Inhibiting Mitophagy in Inner Ear Hair Cells Open
Sensory hearing loss (SNHL) has a high degree of genetic heterogeneity, and there are many mutated genes that cause deafness. GIPC3 gene is one of the mutated genes that can cause congenital hearing loss found in recent years, but the mech…
View article: Clinical significance of postoperative folate receptor‐positive circulating tumor cells (<scp>FR</scp> + <scp>CTCs)</scp> for long‐term prognosis in patients with invasive adenocarcinoma (<scp>IAC</scp>) of the lung
Clinical significance of postoperative folate receptor‐positive circulating tumor cells (<span>FR</span> + <span>CTCs)</span> for long‐term prognosis in patients with invasive adenocarcinoma (<span>IAC</span>) of the lung Open
Background The aim of the study was to evaluate the prognostic value of postoperative folate receptor‐positive circulating tumor cell (FR + CTC) detection in patients with stage I–III invasive adenocarcinoma (IAC) treated with surgery. Met…
View article: The composition of the blood microbiota and its relationship to osteoporosis-related clinical parameters
The composition of the blood microbiota and its relationship to osteoporosis-related clinical parameters Open
Osteoporosis, a systemic bone disease, is characterized by decreased bone mass, deterioration of skeletal structure, and increased bone susceptibility. Age, environment, hormone levels, nutrition, and immunity are all factors that influenc…
View article: Correction: Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model
Correction: Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model Open