Liling Chen
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View article: Thing-Human-Emotion-Beauty model for multi-dimensional perception of cultural relics’ values from the design perspective
Thing-Human-Emotion-Beauty model for multi-dimensional perception of cultural relics’ values from the design perspective Open
The digitalization of museums offers new opportunities for presenting and interpreting cultural artifacts, yet visitor engagement and perceived value often remain limited due to low interactivity and insufficient experiential design. To ad…
View article: Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity
Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity Open
Astrocytes contribute in critical ways to the pathophysiology of epilepsy not only through trophic support but also through the regulation of neuronal excitability by modulating glutamate, γ‐aminobutyric acid (GABA), adenosine triphosphate…
View article: Multi-omics reveals the mechanism of vagus nerve stimulation in the treatment of chronic congestive heart failure
Multi-omics reveals the mechanism of vagus nerve stimulation in the treatment of chronic congestive heart failure Open
View article: Preoperative systemic immune-inflammation index as a predictor of contrast-induced acute kidney injury in coronary artery disease: a multicenter cohort study
Preoperative systemic immune-inflammation index as a predictor of contrast-induced acute kidney injury in coronary artery disease: a multicenter cohort study Open
Preoperative SII may be an independent predictor of CI-AKI risk in CAD patients undergoing undergoing coronary angiography, demonstrating a nonlinear dose-response relationship with a significant threshold effect. These findings suggest th…
View article: Efficacy and Safety Meta-analysis of Whether Denervation Is Combined With Pulmonary Vein Isolation in the Treatment of Hypertension Combined With Atrial Fibrillation
Efficacy and Safety Meta-analysis of Whether Denervation Is Combined With Pulmonary Vein Isolation in the Treatment of Hypertension Combined With Atrial Fibrillation Open
OBJECTIVE To evaluate the effectiveness of denervation sympathectomy (RDN) and pulmonary vein isolation (PVI) for the treatment of hypertension combined with atrial fibrillation (AF) and to examine the safety of the combined procedure. MET…
View article: Life’s Essential 8 metrics and prognosis in patients with renal insufficiency: Results from the National Health and Nutrition Examination Survey, 2007–2018
Life’s Essential 8 metrics and prognosis in patients with renal insufficiency: Results from the National Health and Nutrition Examination Survey, 2007–2018 Open
Background: The benefits of ideal cardiovascular-health metrics (ICVHMs) in patients with renal insufficiency remain unclear. This study aimed to investigate the associations between ICVHM and prognosis in a renal insufficiency population.…
View article: Cerebellum abnormalities in vascular mild cognitive impairment with depression symptom patients: A multimodal magnetic resonance imaging study
Cerebellum abnormalities in vascular mild cognitive impairment with depression symptom patients: A multimodal magnetic resonance imaging study Open
Cerebellar abnormalities, including the gray matter atrophy and RSFC changes, are associated with svMCI, particularly when depression symptoms are present. These results suggest potential diagnostic and therapeutic implications for svMCI a…
View article: Dynamic Changes and Trends of SARS‐CoV‐2 Antibodies Induced by Infection and Vaccination Across Multiple Time Points
Dynamic Changes and Trends of SARS‐CoV‐2 Antibodies Induced by Infection and Vaccination Across Multiple Time Points Open
As the COVID‐19 pandemic continues, increasingly complex vaccination and infection histories have made it urgent to investigate the antibody dynamics in populations with hybrid immunity. This study aimed to explore the multi‐time‐point dyn…
View article: Epitome of the Region—Regional Nostalgia Design Based on Digital Twins
Epitome of the Region—Regional Nostalgia Design Based on Digital Twins Open
Nostalgic scenes can trigger nostalgia to a considerable extent and can be effectively used as a nostalgic trigger that contributes to the psychological comfort of the elderly and immigrant populations, but a design system has not been ade…
View article: Associations of various healthy dietary patterns with biological age acceleration and the mediating role of gut microbiota: results from the China Multi-Ethnic Cohort study
Associations of various healthy dietary patterns with biological age acceleration and the mediating role of gut microbiota: results from the China Multi-Ethnic Cohort study Open
To investigate the associations between dietary patterns and biological ageing, identify the most recommended dietary pattern for ageing and explore the potential mediating role of gut microbiota in less-developed ethnic minority regions (…
View article: Clinical and Diagnostic Value of High-Density Lipoprotein-Based Inflammatory Indices and Lipid Ratios in Young Adults with Schizophrenia
Clinical and Diagnostic Value of High-Density Lipoprotein-Based Inflammatory Indices and Lipid Ratios in Young Adults with Schizophrenia Open
HDL-based inflammatory indices, particularly NHR, may serve as valuable diagnostic and prognostic markers in young adults with schizophrenia, even though significant alterations in lipid ratios were not observed in this demographic.
View article: The Role of Different Systemic Inflammatory Indexes Derived from Complete Blood Count in Differentiating Acute from Chronic Calculus Cholecystitis and Predicting Its Severity
The Role of Different Systemic Inflammatory Indexes Derived from Complete Blood Count in Differentiating Acute from Chronic Calculus Cholecystitis and Predicting Its Severity Open
Systemic inflammation indexes can be useful in predicting the risk of ACC and MS-ACC. NLR demonstrates the best distinguishing power and sensitivity for distinguishing ACC from CCC, while NLPR shows the best predictive power and specificit…
View article: Development of a Canine Model for Chronic Heart Failure Treatment Using a Pacemaker-Compatible Vagus Nerve Stimulation Device
Development of a Canine Model for Chronic Heart Failure Treatment Using a Pacemaker-Compatible Vagus Nerve Stimulation Device Open
This present study aims to develop a vagus nerve stimulator compatible with a pacemaker to treat chronic heart failure(CHF) in a canine model, with the goal of alleviating side effects induced by Vagus Nerve Stimulation (VNS), such as brad…
View article: Research on Regulation Method of Energy Storage System Based on Multi-Stage Robust Optimization
Research on Regulation Method of Energy Storage System Based on Multi-Stage Robust Optimization Open
To address the scheduling problem involving energy storage systems and uncertain energy, we propose a method based on multi-stage robust optimization. This approach aims to regulate the energy storage system by using a multi-stage robust o…
View article: Age-Related Effect of Uric Acid on Contrast-Induced Acute Kidney Injury of Patients Undergoing Coronary Angiography
Age-Related Effect of Uric Acid on Contrast-Induced Acute Kidney Injury of Patients Undergoing Coronary Angiography Open
The association between uric acid and CI-AKI vary in patients of different age. Patients with elder age should maintain a middle level of uric acid while patients with middle age should consider a lower level of uric acid to reduce the ris…
View article: Association of triglyceride-glucose index with the prevalence of cardiovascular disease in malnourished/non-malnourished patients: a large cross-sectional study
Association of triglyceride-glucose index with the prevalence of cardiovascular disease in malnourished/non-malnourished patients: a large cross-sectional study Open
Background Numerous investigations have demonstrated a strong association between the TyG (triglyceride-glucose) index, which is derived from lipid and glucose levels in the bloodstream, and the onset and progression of cardiovascular dise…
View article: Proportion and number of incident cancer deaths in coronary artery disease
Proportion and number of incident cancer deaths in coronary artery disease Open
Background Globally, coronary artery disease (CAD) and cancer are the leading causes of death. Studies focusing on the proportion and spectrum of cancer mortality among CAD patients are lacking. We aim to characterize the proportion and sp…
View article: Elevated urine albumin creatinine ratio increases cardiovascular mortality in coronary artery disease patients with or without type 2 diabetes mellitus: a multicenter retrospective study
Elevated urine albumin creatinine ratio increases cardiovascular mortality in coronary artery disease patients with or without type 2 diabetes mellitus: a multicenter retrospective study Open
View article: Identification and quantitative assessment of motor complications in Parkinson’s disease using the Parkinson’s KinetiGraph™
Identification and quantitative assessment of motor complications in Parkinson’s disease using the Parkinson’s KinetiGraph™ Open
Introduction Effective management and therapies for the motor complications of Parkinson’s disease (PD) require appropriate clinical evaluation. The Parkinson’s KinetiGraph™ (PKG) is a wearable biosensor system that can record the motion c…
View article: Unveiling a New Perspective on Distinguishing Omicron Breakthrough Cases and Postimmune COVID-19-Naive Individuals: Insights from Antibody Profiles
Unveiling a New Perspective on Distinguishing Omicron Breakthrough Cases and Postimmune COVID-19-Naive Individuals: Insights from Antibody Profiles Open
This study fills a gap in the epidemiological evidence by investigating the value of serological indicators, particularly IgG and IgA levels, in the auxiliary diagnosis of COVID-19 infections when nucleic acid results are undetectable. The…
View article: The aggregate index of systemic inflammation (AISI): a novel predictor for hypertension
The aggregate index of systemic inflammation (AISI): a novel predictor for hypertension Open
Objective Inflammation plays an important role in the pathophysiology of hypertension (HTN). Aggregate index of systemic inflammation (AISI), as a new inflammatory and prognostic marker has emerged recently. Our goal was to determine wheth…
View article: Advanced lung cancer inflammation index is associated with long-term cardiovascular death in hypertensive patients: national health and nutrition examination study, 1999–2018
Advanced lung cancer inflammation index is associated with long-term cardiovascular death in hypertensive patients: national health and nutrition examination study, 1999–2018 Open
Background: Hypertension is one of the main causes of cardiovascular death. Inflammation was considered influential factors of cardiovascular (CVD) death in patients with hypertension. Advanced lung cancer inflammation index (ALI) is an in…
View article: Mediation Effect of Obesity on the Association of Age at Menarche With Blood Pressure Among Women in Southwest China
Mediation Effect of Obesity on the Association of Age at Menarche With Blood Pressure Among Women in Southwest China Open
Background Previous studies have been inconsistent about the association between age at menarche and high blood pressure. Little is known about such association across a wide range of menarcheal ages in less developed ethnic minority regio…
View article: Copeptin Reflect Left Ventricular Systolic Function at Early Stage of Acute Myocardial Infarction in a Pig Model
Copeptin Reflect Left Ventricular Systolic Function at Early Stage of Acute Myocardial Infarction in a Pig Model Open
Introduction: Measurement of biomarkers early after acute myocardial infarction (AMI) might provide a cost-effective and widely available tool to assess infarct severity, myocardial dysfunction, and clinical outcomes. We aimed to induce AM…
View article: Alzheimer’s disease and epilepsy: An increasingly recognized comorbidity
Alzheimer’s disease and epilepsy: An increasingly recognized comorbidity Open
Both Alzheimer’s disease (AD) and epilepsy are common chronic diseases in older people. Seizures and epileptiform discharges are very prevalent in AD and can occur since any stage of AD. Increasing evidence indicates that AD and epilepsy m…
View article: Effect of Dietary Salt Intake on Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Case-Control Studies
Effect of Dietary Salt Intake on Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Case-Control Studies Open
Aim: The effect of dietary salt intake on the risk of gastric cancer is not clear. A meta-analysis was performed to estimate the association between dietary salt intake and the risk of gastric cancer. Methods: Three major databases were se…
View article: Nutrition-related diseases and cardiovascular mortality in American society: national health and nutrition examination study, 1999–2006
Nutrition-related diseases and cardiovascular mortality in American society: national health and nutrition examination study, 1999–2006 Open
View article: Prevalence and Prognostic Impact of Malnutrition in Critical Patients With Acute Myocardial Infarction: Results From Chinese CIN Cohort and American MIMIC-III Database
Prevalence and Prognostic Impact of Malnutrition in Critical Patients With Acute Myocardial Infarction: Results From Chinese CIN Cohort and American MIMIC-III Database Open
Background Malnutrition is associated with poor prognosis in patients with acute myocardial infarction (AMI). However, the prognostic impact of malnutrition in critical patients with AMI has not been well addressed. Methods We analyzed two…
View article: Modulating the Band Structure of Metal Coordinated Salen COFs and an In Situ Constructed Charge Transfer Heterostructure for Electrocatalysis Hydrogen Evolution
Modulating the Band Structure of Metal Coordinated Salen COFs and an In Situ Constructed Charge Transfer Heterostructure for Electrocatalysis Hydrogen Evolution Open
A series of crystalline, stable Metal (Metal = Zn, Cu, Ni, Co, Fe, and Mn)‐Salen covalent organic framework (COF) EDA complex are prepared to continuously tune the band structure of Metal‐Salen COF EDA , with the purpose of optimizing the …
View article: A Synergistic Association Between Inflammation, Malnutrition, and Mortality in Patients With Diabetics
A Synergistic Association Between Inflammation, Malnutrition, and Mortality in Patients With Diabetics Open
Background Although inflammation is a known predictor for poor prognosis in patients with diabetics, few data report the synergistic association between inflammation, malnutrition, and mortality in patients with diabetics. We aim to explor…