Lillian Moraes
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View article: CLINICAL OUTCOMES, USE OF INVASIVE MECHANICAL VENTILATION AND RENAL REPLACEMENT THERAPY OF ADULT AND ELDERLY PATIENTS HOSPITALIZED WITH COVID-19: A RETROSPECTIVE COHORT
CLINICAL OUTCOMES, USE OF INVASIVE MECHANICAL VENTILATION AND RENAL REPLACEMENT THERAPY OF ADULT AND ELDERLY PATIENTS HOSPITALIZED WITH COVID-19: A RETROSPECTIVE COHORT Open
Objective: To compare the clinical and epidemiological outcomes of 1,266 patients hospitalized with COVID-19 in a private hospital in northeastern Brazil to identify differences according to age group. Methods: This observational, descript…
View article: Nutritional status and metabolic alterations in patients with ataxia-telangiectasia
Nutritional status and metabolic alterations in patients with ataxia-telangiectasia Open
Background Ataxia-telangiectasia (A-T) is a DNA repair disorder characterized by progressive degeneration, immunodeficiency, cancer predisposition, malnutrition, metabolic disorders, and chronic liver disease. The study aims to describe th…
View article: Applying Vision Transformers on Spectral Analysis of Astronomical Objects
Applying Vision Transformers on Spectral Analysis of Astronomical Objects Open
We apply pre-trained Vision Transformers (ViTs), originally developed for image recognition, to the analysis of astronomical spectral data. By converting traditional one-dimensional spectra into two-dimensional image representations, we en…
View article: Ataxia Telangiectasia in Latin America: clinical features, immunodeficiency and mortality in a multicenter study
Ataxia Telangiectasia in Latin America: clinical features, immunodeficiency and mortality in a multicenter study Open
Ataxia-telangiectasia (AT) is a rare neurodegenerative genetic disorder leading to neurological defects, telangiectasias and immunodeficiency. We aimed to study the clinical and immunological features of Latin American patients with AT and…
View article: Impact of different frequencies of controlled breath and pressure-support levels during biphasic positive airway pressure ventilation on the lung and diaphragm in experimental mild acute respiratory distress syndrome
Impact of different frequencies of controlled breath and pressure-support levels during biphasic positive airway pressure ventilation on the lung and diaphragm in experimental mild acute respiratory distress syndrome Open
Background We hypothesized that a decrease in frequency of controlled breaths during biphasic positive airway pressure (BIVENT), associated with an increase in spontaneous breaths, whether pressure support (PSV)-assisted or not, would miti…
View article: Prevalence and clinical characteristics of wheezing in children in the first year of life, living in Cuiabá, Mato Grosso, Brazil
Prevalence and clinical characteristics of wheezing in children in the first year of life, living in Cuiabá, Mato Grosso, Brazil Open
OBJECTIVE: To evaluate the prevalence and the clinical characteristics of wheezing in infants aged 12 to 15 months in the city of Cuiabá, Mato Grosso State, Midwest Brazil.METHODS: Parents and/or guardians of infants were interviewed and c…
View article: Impact of Different Tidal Volume Levels at Low Mechanical Power on Ventilator-Induced Lung Injury in Rats
Impact of Different Tidal Volume Levels at Low Mechanical Power on Ventilator-Induced Lung Injury in Rats Open
Tidal volume (VT) has been considered the main determinant of ventilator-induced lung injury (VILI). Recently, experimental studies have suggested that mechanical power transferred from the ventilator to the lungs is the promoter of VILI. …
View article: Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome
Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome Open
Background The authors hypothesized that low tidal volume (V T ) would minimize ventilator-induced lung injury regardless of the degree of mechanical power. The authors investigated the impact of power, obtained by different combinations o…
View article: Biological Response to Time-Controlled Adaptive Ventilation Depends on Acute Respiratory Distress Syndrome Etiology*
Biological Response to Time-Controlled Adaptive Ventilation Depends on Acute Respiratory Distress Syndrome Etiology* Open
Objectives: To compare a time-controlled adaptive ventilation strategy, set in airway pressure release ventilation mode, versus a protective mechanical ventilation strategy in pulmonary and extrapulmonary acute respiratory distress syndrom…
View article: Effects of pressure support ventilation on ventilator-induced lung injury in mild acute respiratory distress syndrome depend on level of positive end-expiratory pressure
Effects of pressure support ventilation on ventilator-induced lung injury in mild acute respiratory distress syndrome depend on level of positive end-expiratory pressure Open
During PSV, PEEP of 5 cmH2O, but not a PEEP of 2 cmH2O, reduced lung damage and inflammatory markers while maintaining epithelial cell integrity.
View article: Effects of pressure support and pressure-controlled ventilation on lung damage in a model of mild extrapulmonary acute lung injury with intra-abdominal hypertension
Effects of pressure support and pressure-controlled ventilation on lung damage in a model of mild extrapulmonary acute lung injury with intra-abdominal hypertension Open
Intra-abdominal hypertension (IAH) may co-occur with the acute respiratory distress syndrome (ARDS), with significant impact on morbidity and mortality. Lung-protective controlled mechanical ventilation with low tidal volume and positive e…
View article: Variable Ventilation Improved Respiratory System Mechanics and Ameliorated Pulmonary Damage in a Rat Model of Lung Ischemia-Reperfusion
Variable Ventilation Improved Respiratory System Mechanics and Ameliorated Pulmonary Damage in a Rat Model of Lung Ischemia-Reperfusion Open
Lung ischemia-reperfusion injury remains a major complication after lung transplantation. Variable ventilation (VV) has been shown to improve respiratory function and reduce pulmonary histological damage compared to protective volume-contr…