Vuanghao Lim
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View article: Dietary Supplementation of Lotus (Nelumbo nucifera Gaertn.) Extract Alleviates Liver Injury Induced by 2-Methoxyethanol in Mice Model
Dietary Supplementation of Lotus (Nelumbo nucifera Gaertn.) Extract Alleviates Liver Injury Induced by 2-Methoxyethanol in Mice Model Open
2-Methoxyethanol (2-ME), a phthalic acid ester widely used in the plastics industry, can cause liver injury. Natural plant substances with antioxidant properties are promising candidates for alleviating such injury. While hepatoprotective …
View article: Anti-angiogenic effects of Moringa oleifera silver nanoparticles on endothelial cells: in vitro and ex vivo studies
Anti-angiogenic effects of Moringa oleifera silver nanoparticles on endothelial cells: in vitro and ex vivo studies Open
Aim: Angiogenesis, invasion, and tube formation are critical processes in tumor progression and metastasis. The use of nanoparticles derived from natural products presents a promising approach for targeted cancer therapy. This study evalua…
View article: Potential of Macang (Mangifera foetida) Bark Extract on Antioxidant Levels and Pro-Apoptotic Proteins in Rats (Rattus norvegicus) Exposed to Polystyrene Nanoplastics
Potential of Macang (Mangifera foetida) Bark Extract on Antioxidant Levels and Pro-Apoptotic Proteins in Rats (Rattus norvegicus) Exposed to Polystyrene Nanoplastics Open
Nanoplastics in the environment primarily originate from contaminated aquatic animals, detergent waste, and cosmetic products, which can accumulate in the body through ingestion, inhalation, and skin exposure. This accumulation poses signi…
View article: Adverse Effect of Polystyrene Nanoplastics in Impairing Glucose Metabolism in Liver Injury
Adverse Effect of Polystyrene Nanoplastics in Impairing Glucose Metabolism in Liver Injury Open
Polystyrene nanoplastics (PS-NPs) are result from the degradation of plastic and have diameters ranging from 1 nm to 100 nm. The objective of this study is to provide information on the adverse effects of PS-NPs with in vitro and in vivo a…
View article: Emerging insights into mesenchymal stem cells and exosome-based therapies for liver injury
Emerging insights into mesenchymal stem cells and exosome-based therapies for liver injury Open
Hepatic ischemia-reperfusion injury, fatty liver, liver fibrosis, liver peroxidative injury, and drug-induced liver injury are among the most common liver diseases. Mesenchymal stem cells (MSCs) possess multi-lineage differentiation potent…
View article: Metabolomics in Chronic Kidney Disease: The Emerging Role in Detection and Diagnosis of Mineral and Bone Disorders
Metabolomics in Chronic Kidney Disease: The Emerging Role in Detection and Diagnosis of Mineral and Bone Disorders Open
Chronic kidney disease (CKD) affects over 10% of the global population and is increasingly prevalent, placing a substantial strain on healthcare systems. In Malaysia, CKD prevalence rose from 9.05% in 2011 to 15.48% in 2018, largely driven…
View article: Potential of Cinnamomum burmanni Leaf Extract as an Exogenous Antioxidant and Spermatoprotective for Rattus norvegicus L. Exposed to Polystyrene Nanoplastics
Potential of Cinnamomum burmanni Leaf Extract as an Exogenous Antioxidant and Spermatoprotective for Rattus norvegicus L. Exposed to Polystyrene Nanoplastics Open
Polytyrene nanoplastics (NPs) (<1 µm) have high toxicity when entered and accumulated in cells. NPs accumulation causes oxidation stress, thus increasing reactive oxygen species (ROS) production, resulting in necrosis or apoptosis, as well…
View article: Improving the anticancer efficacy of tetrahydrocurcumin via β-cyclodextrin inclusion complexation
Improving the anticancer efficacy of tetrahydrocurcumin via β-cyclodextrin inclusion complexation Open
Context: Tetrahydrocurcumin (THC) exhibits superior biological and pharmacological characteristics compared to curcumin, demonstrating efficacy in suppressing tumor metastasis and angiogenesis and acting as a potent preventive agent agains…
View article: Antioxidant Potential of <i>Mangifera foetida</i> Bark, <i>Mangifera foetida</i> Leaves, and <i>Cinnamomum burmanii</i> Leaves Extract in Mitigating Nanoplastic‐Induced Toxicity and Disruption of Glycolipid Metabolism
Antioxidant Potential of <i>Mangifera foetida</i> Bark, <i>Mangifera foetida</i> Leaves, and <i>Cinnamomum burmanii</i> Leaves Extract in Mitigating Nanoplastic‐Induced Toxicity and Disruption of Glycolipid Metabolism Open
Pollution from plastic waste has become an urgent issue, requiring solutions to prevent and mitigate diseases caused by plastic waste, particularly those involving nanoplastics (NP). This study specifically focused on investigating the exo…
View article: Protective Effects of Nelumbo nucifera Extracts on Lung Exposed to Polystyrene Nanoplastics; Histological and Phytochemical Analysis
Protective Effects of Nelumbo nucifera Extracts on Lung Exposed to Polystyrene Nanoplastics; Histological and Phytochemical Analysis Open
Polystyrene nanoplastics (Ps-NPs) are emerging environmental contaminants known to cause significant respiratory damage due to oxidative stress and inflammation. This study aimed to evaluate the protective effects of Nelumbo nucifera extra…
View article: Comparing the Toxicity Effect Induced by Bisphenol A and Bisphenol S In the Zebrafish Model
Comparing the Toxicity Effect Induced by Bisphenol A and Bisphenol S In the Zebrafish Model Open
Introduction: With the shift from Bisphenol A (BPA) to Bisphenol S (BPS) in consumer products, there is limited knowledge on BPS's impact on human health. This study compares the toxicity of BPA and BPS on zebrafish embryos. Materials and …
View article: Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells.
Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells. Open
EEROP treatment reduces β-catenin protein levels, promotes abnormal spindle apparatus segregation, and finally leads to apoptotic cell death in CRC cells.
View article: Antimetastatic effect of nanodiamond-conjugated quercetin against colon cancer: an in vivo study
Antimetastatic effect of nanodiamond-conjugated quercetin against colon cancer: an in vivo study Open
NDQ increased Q's anticancer activity, suggesting that NDs have an effective drug delivery property.
View article: Medicinal activities of Tualang honey: a systematic review
Medicinal activities of Tualang honey: a systematic review Open
Natural products derived from various sources, including plants, have garnered significant interest as alternative therapeutic options. Among these, Tualang honey, extracted from the nectar of Tualang trees (Koompassia excelsa (Becc.) Taub…
View article: Unveiling fucoxanthin's fate: In vitro gastrointestinal digestion effects on bioaccessibility, antioxidant potential, colour changes, and metabolite profiles
Unveiling fucoxanthin's fate: In vitro gastrointestinal digestion effects on bioaccessibility, antioxidant potential, colour changes, and metabolite profiles Open
Limited knowledge of fucoxanthin's changes during digestion necessitates comprehensive investigation to ensure its efficacy as a functional ingredient. This study assessed the effects of digestion on fucoxanthin's bioaccessibility, antioxi…
View article: Assessing the impact of temperature, <scp>pH</scp>, light and chemical oxidation on fucoxanthin colour changes, antioxidant activity and the resulting metabolites
Assessing the impact of temperature, <span>pH</span>, light and chemical oxidation on fucoxanthin colour changes, antioxidant activity and the resulting metabolites Open
BACKGROUND The present study evaluated the effects of temperature, pH, light and chemical oxidation on fucoxanthin changes in terms of colour, antioxidant activity and metabolomic profile. Additionally, the correlation between antioxidant …
View article: In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease
In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease Open
Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves (Dendrophthoe pentandra L. Miq), also known as Benalu Duku (BD), have antimicrobial effects. Thus, the plant has the…
View article: Plant Essential Oil Nanoemulgel as a Cosmeceutical Ingredient: A Review
Plant Essential Oil Nanoemulgel as a Cosmeceutical Ingredient: A Review Open
Essential oils (EOs) are concentrated, hydrophobic volatile compounds derived from different parts of plants. They are recognized for their diverse and versatile functional properties. Approximately 90% of EOs are administered via topical …
View article: In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease
In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease Open
Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves ( Dendrophthoe pentandra L. Miq ), also known as Benalu Duku (BD), have antimicrobial effects. Thus, the plant has …
View article: Network Pharmacology and Molecular Docking Approaches of Astaxanthin (ATX) against Atherosclerosis
Network Pharmacology and Molecular Docking Approaches of Astaxanthin (ATX) against Atherosclerosis Open
Pharmacognosy Research,2024,16,3,626-637.DOI:10.5530/pres.16.3.74Published:June 2024Type:Original ArticleAuthors:Anis Zuhaida Mamnun Barizi, Ain Nabila Syahira Shamsol Azman, Muhamad Fikri Shazlan Saad, Muhammad Nazrul Hakim Abdullah, Vuan…
View article: In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease
In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease Open
Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves ( Dendrophthoe pentandra L. Miq ), also known as Benalu Duku (BD), have antimicrobial effects. Thus, the plant has …
View article: Formation of Inclusion Complex of Curcumin and Tetrahydrocurcumin Prevents Angiogenesis by Inhibiting VEGF Activity: An in-Silico Study
Formation of Inclusion Complex of Curcumin and Tetrahydrocurcumin Prevents Angiogenesis by Inhibiting VEGF Activity: An in-Silico Study Open
Curcumin and tetrahydrocurcumin (THC) are known for their anticancer properties, but limited solubility in water hinders their effectiveness against cancer. In this study, we conducted an in silico exploration of β-cyclodextrin's potential…
View article: In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease
In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease Open
Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves ( Dendrophthoe pentandra L. Miq ), also known as Benalu Duku (BD), have antimicrobial effects. Thus, the plant has …
View article: Critical Evaluation of Green Synthesized Silver Nanoparticles-Kaempferol for Antibacterial Activity Against Methicillin-Resistant Staphylococcus aureus
Critical Evaluation of Green Synthesized Silver Nanoparticles-Kaempferol for Antibacterial Activity Against Methicillin-Resistant Staphylococcus aureus Open
The presence of a dark brown colour in the solution indicated the formation of AgNP-K. The UV-visible absorption spectrum of the synthesized AgNP-K exhibited a broad peak at 447 nm. TEM, Zetasizer, and SEM-EDX results showed that the morph…
View article: Impact of prolonged storage on quality assessment properties and constituents of honey: A systematic review
Impact of prolonged storage on quality assessment properties and constituents of honey: A systematic review Open
This systematic review paper aims to discuss the trend in quality assessment properties and constituents of honey at different storage conditions and confer the possible whys and wherefores associated with the significant changes. Initiall…
View article: Exploring stingless bee honey from selected regions of Peninsular Malaysia through gas chromatography–mass spectrometry–based untargeted metabolomics
Exploring stingless bee honey from selected regions of Peninsular Malaysia through gas chromatography–mass spectrometry–based untargeted metabolomics Open
Volatile organic compounds in honey are known for their considerable impact on the organoleptic properties of honey, such as aroma, flavor, taste, and texture. The type and composition of volatile organic compounds are influenced by entomo…