Jiyang Li
YOU?
Author Swipe
View article: SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks
SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks Open
Single‐cell cis‐regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease‐associated non‐coding variants. Existing computational methods struggle to accu…
View article: ChromFound: Towards A Universal Foundation Model for Single-Cell Chromatin Accessibility Data
ChromFound: Towards A Universal Foundation Model for Single-Cell Chromatin Accessibility Data Open
The advent of single-cell Assay for Transposase-Accessible Chromatin using sequencing (scATAC-seq) offers an innovative perspective for deciphering regulatory mechanisms by assembling a vast repository of single-cell chromatin accessibilit…
View article: SCRIPT: predicting single-cell long-range <i>cis</i> -regulation based on pretrained graph attention networks
SCRIPT: predicting single-cell long-range <i>cis</i> -regulation based on pretrained graph attention networks Open
Single-cell cis -regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease-associated non-coding variants. Existing computational methods struggle to acc…
View article: Longitudinal Wrist PPG Analysis for Reliable Hypertension Risk Screening Using Deep Learning
Longitudinal Wrist PPG Analysis for Reliable Hypertension Risk Screening Using Deep Learning Open
Hypertension is a leading risk factor for cardiovascular diseases. Traditional blood pressure monitoring methods are cumbersome and inadequate for continuous tracking, prompting the development of PPG-based cuffless blood pressure monitori…
View article: Correction: Deep Shotgun metagenomic and 16S rRNA analysis revealed the microbial diversity of lactic acid bacteria in traditional fermented foods of eastern Hainan, China
Correction: Deep Shotgun metagenomic and 16S rRNA analysis revealed the microbial diversity of lactic acid bacteria in traditional fermented foods of eastern Hainan, China Open
Correction for ‘Deep Shotgun metagenomic and 16S rRNA analysis revealed the microbial diversity of lactic acid bacteria in traditional fermented foods of eastern Hainan, China’ by Yuqing Wu et al. , Food Funct. , 2022, 13 , 12938–12952, ht…
View article: Bibliometric analysis of research on Alzheimer’s disease and non-coding RNAs: Opportunities and challenges
Bibliometric analysis of research on Alzheimer’s disease and non-coding RNAs: Opportunities and challenges Open
Background Non-coding RNAs (ncRNA) are a kind of RNA that does not encode protein, which play an important role in Alzheimer’s disease (AD). However, there is a lack of bibliometric analysis and visualization analysis of the research relat…
View article: A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment
A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment Open
Background The rumen microbiota provides essential services to its host and, through its role in ruminant production, contributes to human nutrition and food security. A thorough knowledge of the genetic potential of rumen microbes will pr…
View article: Synthesis and Cell Division Cycle 25B Phosphatase and Protein Ty-rosine Phosphatase 1B Inhibitory Activity Evaluation of Novel 3,6-Disubstituted Triazolothiadiazole Derivatives
Synthesis and Cell Division Cycle 25B Phosphatase and Protein Ty-rosine Phosphatase 1B Inhibitory Activity Evaluation of Novel 3,6-Disubstituted Triazolothiadiazole Derivatives Open
张 楠 a 王思远 a 李 佳 * ,b ( a 辽宁师范大学化学化工学院 大连 116029) ( b 中国科学院上海药物研究所 国家新药筛选中心 药物研究国家重点实验室 上海 201203) ( c 大连理工大学精细化工国家重点实验室 大连 116012) 摘要 以邻苯二胺和一氯乙酸为初始原料, 经多步反应, 合成了一系列新型含苯并咪唑环和芳磺酰基的 3,6-二取代三 唑并噻二唑衍生物 7a～7y.利用 1 H NMR、IR 和元素分析对新的中间体化合物 3、4、6 及…
View article: Chlorogenic acid prevents isoproterenol-induced DNA damage in vascular smooth muscle cells
Chlorogenic acid prevents isoproterenol-induced DNA damage in vascular smooth muscle cells Open
Numerous clinical therapeutic agents have been identified as DNA damaging. The present study revealed that isoproterenol (Iso) resulted in DNA damage in vascular smooth muscle cells (VSMCs) and increased the levels of intracellular oxygen …