Liming Dong
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View article: Role and research progress of hip arthroscopy in the treatment of pre-collapse osteonecrosis of the femoral head
Role and research progress of hip arthroscopy in the treatment of pre-collapse osteonecrosis of the femoral head Open
Background This study is to provide a detailed overview of the application value of hip arthroscopy in the treatment of pre-collapse ischemic necrosis of the femoral head (ONFH) and summarizes the latest research progress. Methods Using th…
View article: Multi‑omics reveal neutrophil heterogeneity in sepsis (Review)
Multi‑omics reveal neutrophil heterogeneity in sepsis (Review) Open
Sepsis is a life‑threatening disease characterized by a dysregulated immune response, and neutrophils serve an important role in pathogen clearance, multiple organ failure and immune regulation. With the discovery of multiple phenotypical …
View article: Integrating Machine Learning and Multi-Omics to Explore Neutrophil Heterogeneity
Integrating Machine Learning and Multi-Omics to Explore Neutrophil Heterogeneity Open
Traditionally considered as homogeneous innate immune cells, neutrophils are now found to exhibit phenotypic and functional heterogeneity. How to determine whether the functional changes of neutrophils are caused by activation or the resul…
View article: An Ignored killer: the burden of Cyclist road injuries in China from the Global Burden of Disease Study 2021
An Ignored killer: the burden of Cyclist road injuries in China from the Global Burden of Disease Study 2021 Open
Objective To quantify the burden, trends, and gender-specific disparities of cyclist road injuries in China following the micro-mobility revolution and identify systemic drivers of rising mortality among reproductive-aged women. Methods Us…
View article: The Emerging Roles and Therapeutic Potential of Unconventional T Cells in Sepsis
The Emerging Roles and Therapeutic Potential of Unconventional T Cells in Sepsis Open
Sepsis represents a dynamic, dysregulated host immune response to infection in which unconventional T cells-γδ T cells, mucosal-associated invariant T (MAIT) cells, natural killer T (NKT) cells, and double-negative T cells-actively shape t…
View article: Knowledge, attitude, practice, and influencing factors among patients with osteonecrosis of the femoral head
Knowledge, attitude, practice, and influencing factors among patients with osteonecrosis of the femoral head Open
Osteonecrosis of the femoral head affects young adults, often requiring THA due to compromised blood supply and hip pain. To assess the knowledge, attitudes, and practices (KAP) regarding avascular necrosis in patients. A cross-sectional s…
View article: Software Security Mapping Framework: Operationalization of Security Requirements
Software Security Mapping Framework: Operationalization of Security Requirements Open
The escalating complexity of modern software development environments has heightened concerns around supply chain security. However, existing frameworks often fall short in translating abstract security principles into concrete, actionable…
View article: Adaptation of Natural Killer Cells to Hypoxia: A Review of the Transcriptional, Translational, and Metabolic Processes
Adaptation of Natural Killer Cells to Hypoxia: A Review of the Transcriptional, Translational, and Metabolic Processes Open
As important innate immune cells, natural killer (NK) cells play an essential role in resisting pathogen invasion and eliminating transformed cells. However, the hypoxic microenvironment caused by disease conditions is an important physico…
View article: Is polytrauma really just a simple accident? Recurrent characteristic of polytrauma
Is polytrauma really just a simple accident? Recurrent characteristic of polytrauma Open
Polytrauma recidivism is associated with a high recurrence rate, poorer clinical outcomes, and elevated healthcare costs. Key predictive markers for recidivism include being male, aged 45-54 years, experiencing sleep deprivation, employmen…
View article: EXPLORING THE MOTHER-DAUGHTER RELATIONSHIP FROM BIOGRAPHICAL AND PSYCHOLOGICAL PERSPECTIVES
EXPLORING THE MOTHER-DAUGHTER RELATIONSHIP FROM BIOGRAPHICAL AND PSYCHOLOGICAL PERSPECTIVES Open
Amy Tan’s novels serve as an in-depth study of mother-daughter relationships, intergenerational conflicts, and the thirst for identity amidst cultural and familial dynamics. Through her extraordinary narratives, Tan delves into the complex…
View article: From trauma to chronicity: Understanding the incidence and early immune changes of chronic complications in polytrauma patients
From trauma to chronicity: Understanding the incidence and early immune changes of chronic complications in polytrauma patients Open
Objective Polytrauma is a complex condition associated with poor outcomes and high mortality rates resulting from severe damage and complicated complications. This study sought to ascertain the incidence of chronic complications in polytra…
View article: SDACS: Blockchain-Based Secure and Dynamic Access Control Scheme for Internet of Things
SDACS: Blockchain-Based Secure and Dynamic Access Control Scheme for Internet of Things Open
With the rapid growth of the Internet of Things (IoT), massive terminal devices are connected to the network, generating a large amount of IoT data. The reliable sharing of IoT data is crucial for fields such as smart home and healthcare, …
View article: Acute Gastrointestinal Injury in Polytrauma: Special Attention to Elderly Patients
Acute Gastrointestinal Injury in Polytrauma: Special Attention to Elderly Patients Open
Background: Acute gastrointestinal injury (AGI) has been documented in critically ill patients, yet there remains a dearth of knowledge regarding its occurrence, predisposing factors, and outcomes in elderly polytrauma patients, a signific…
View article: CCDC 2240817: Experimental Crystal Structure Determination
CCDC 2240817: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2150876: Experimental Crystal Structure Determination
CCDC 2150876: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2257777: Experimental Crystal Structure Determination
CCDC 2257777: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2257778: Experimental Crystal Structure Determination
CCDC 2257778: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Advances in attractive therapeutic approach for macrophage activation syndrome in COVID-19
Advances in attractive therapeutic approach for macrophage activation syndrome in COVID-19 Open
Nowadays, people have relaxed their vigilance against COVID-19 due to its declining infection numbers and attenuated virulence. However, COVID-19 still needs to be concern due to its emerging variants, the relaxation of restrictions as wel…
View article: Discovery of Cycloalkyl[<i>c</i>]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2α Inhibitors
Discovery of Cycloalkyl[<i>c</i>]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2α Inhibitors Open
Hypoxia-inducible factors (HIFs) are heterodimeric transcription factors induced in diverse pathophysiological settings. Inhibition of HIF-2α has become a strategy for cancer treatment since the discovery that small molecules, upon binding…
View article: Venous Thrombus Embolism in Polytrauma: Special Attention to Patients with Traumatic Brain Injury
Venous Thrombus Embolism in Polytrauma: Special Attention to Patients with Traumatic Brain Injury Open
Venous thrombus embolism (VTE) is common after polytrauma, both of which are considered significant contributors to poor outcomes and mortality. Traumatic brain injury (TBI) is recognized as an independent risk factor for VTE and one of th…
View article: Metrics for Software Process Simulation Modeling
Metrics for Software Process Simulation Modeling Open
Background: Software Process Simulation (SPS) has become an effective tool for software process management and improvement. However, its adoption in industry is less than what the research community expected due to the burden of measuremen…