Lin Ma
YOU?
Author Swipe
View article: Study on Gene Mutations of Hereditary Heart Diseases in Cases of Yunnan Sudden Unexplained Death
Study on Gene Mutations of Hereditary Heart Diseases in Cases of Yunnan Sudden Unexplained Death Open
Background Yunnan sudden unexplained death (YNSUD) is a regional public health issue with unclear etiology, characterized by temporal, geographical, and familial clustering. This study aimed to identify pathogenic genetic mutations in here…
View article: Characterization of transmitted drug resistance among recently infected HIV-1 men who have sex with men in Hebei Province, China
Characterization of transmitted drug resistance among recently infected HIV-1 men who have sex with men in Hebei Province, China Open
Despite transmitted drug resistance (TDR) surveillance is the critical role in HIV-1 prevention strategies, epidemiological data remain scarce for newly infected men who have sex with men (MSM) in Hebei Province, China. To address this dat…
View article: Photodynamic Therapy for Facial Port-Wine Stain in a 2-Year-Old Boy
Photodynamic Therapy for Facial Port-Wine Stain in a 2-Year-Old Boy Open
View article: Retrospective study of hemoporfin photodynamic therapy for the GNA-Related Capillary Malformation spectrum
Retrospective study of hemoporfin photodynamic therapy for the GNA-Related Capillary Malformation spectrum Open
View article: Pediatric Mycoplasma pneumoniae-induced rash and mucositis in China: clinical spectrum, co-infections and risk factors for recurrence—a retrospective cohort study
Pediatric Mycoplasma pneumoniae-induced rash and mucositis in China: clinical spectrum, co-infections and risk factors for recurrence—a retrospective cohort study Open
Background Mycoplasma pneumoniae –induced rash and mucositis (MIRM) is a unique entity distinct from both erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis. There are limited data on pediatric cases of MIRM in Chi…
View article: Artemisia annua Extract Ameliorates Atopic Dermatitis: Evidence from 3D Epidermal Model and Complementary in vitro Assays
Artemisia annua Extract Ameliorates Atopic Dermatitis: Evidence from 3D Epidermal Model and Complementary in vitro Assays Open
1% AAE inhibits inflammation and promotes skin barrier function in an AD-like 3D epidermal equivalent model. AAE which mainly includes Arteannuin B, Chlorogenic Acid, Chrysoplenol D, Scopolin, and Vitexicarpin is identified as the putative…
View article: Efficacy and safety of benvitimod 1% cream for atopic dermatitis in patients aged 2 years and older: A phase III randomized clinical trial
Efficacy and safety of benvitimod 1% cream for atopic dermatitis in patients aged 2 years and older: A phase III randomized clinical trial Open
Background: Benvitimod (tapinarof), an aryl hydrocarbon receptor (AhR) agonist approved for treating plaque psoriasis, is being investigated as a potential treatment for atopic dermatitis (AD). The aim of this study was to evaluate the eff…
View article: Traumatic Pneumopericardium in A 14-Year-Old Adolescent: A Report of a Rare Case
Traumatic Pneumopericardium in A 14-Year-Old Adolescent: A Report of a Rare Case Open
Pneumopericardium is a rare condition defined by the presence of air within the pericardial cavity. We report the clinical case of a 14-year-old adolescent girl admitted to the emergency department following a fall from the third floor (a …
View article: The interaction between the skin microbiome and antimicrobial peptides within the epidermal immune microenvironment: Bridging insights into atopic dermatitis
The interaction between the skin microbiome and antimicrobial peptides within the epidermal immune microenvironment: Bridging insights into atopic dermatitis Open
The epidermal immune microenvironment is a multifaceted system in which the interplay between the skin microbiome and antimicrobial peptides plays a pivotal role in sustaining skin homeostasis and preventing dysbiosis. Disruption of these …
View article: Disease burden and changing trend of tracheal, bronchus, and lung cancer attributable to tobacco, globally and in China, the USA, the Russian Federation, and India, 1990–2021
Disease burden and changing trend of tracheal, bronchus, and lung cancer attributable to tobacco, globally and in China, the USA, the Russian Federation, and India, 1990–2021 Open
Over the past three decades, tobacco-attributable TBL disease burden has declined globally and in the USA, the Russian Federation, and India, but continues rising in China, where male and elderly populations (60+ years) bear disproportiona…
View article: Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China
Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China Open
Multi-omics profiling of the infant gut at 42 days identified microbial and metabolic features associated with later AD development. These findings support the gut-skin axis and suggest potential early-life biomarkers for predicting AD ris…
View article: Epidemiology and future trend predictions of ischemic stroke based on the global burden of disease study 1990–2021
Epidemiology and future trend predictions of ischemic stroke based on the global burden of disease study 1990–2021 Open
View article: Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies
Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies Open
Depression is the most common psychiatric comorbidity of epilepsy. While antiseizure medications (ASMs) can exacerbate depressive symptoms, depression itself may increase both the frequency and duration of epileptic seizures. The pathophys…
View article: Population Pharmacokinetics and Exposure‐Response Relationship of Hemoporfin in Pediatric Patients With Port‐Wine Stain
Population Pharmacokinetics and Exposure‐Response Relationship of Hemoporfin in Pediatric Patients With Port‐Wine Stain Open
Hemoporfin, a porphyrin derivative photosensitizer, has been approved for the treatment of port‐wine stain (PWS) in adults. However, its optimal dose for the pediatric population remains unclear. This study aimed to explore appropriate dos…
View article: Significance of gene therapy in neurodegenerative diseases
Significance of gene therapy in neurodegenerative diseases Open
Gene therapy is an approach that employs vectors to deliver genetic material to target cells, aiming to correct genes with pathogenic mutations and modulate one or more genes responsible for disease progression. It holds significant value …
View article: Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants?
Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? Open
Colloidal oat emollients are effective, well-tolerated, and cost-efficient for pediatric AD management. Their barrier-restorative and anti-inflammatory properties may reduce AD and allergy risk. Future research should focus on head-to-head…
View article: Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study
Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study Open
Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understandi…
View article: A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areas
A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areas Open
This study provides robust real-world evidence that PIM 1% cream is effective for the treatment of mild-to-moderate AD in Chinese patients, particularly in sensitive skin areas and paediatric population. PIM also offers a TCS-sparing appro…
View article: 花岗伟晶岩与花岗岩的关系
花岗伟晶岩与花岗岩的关系 Open
View article: Epidemic trend, genetic characteristics, and transmission networks of HIV-1 among treatment-naive men who have sex with men in Hebei province, China
Epidemic trend, genetic characteristics, and transmission networks of HIV-1 among treatment-naive men who have sex with men in Hebei province, China Open
Introduction Homosexual transmission has contributed greatly to the current HIV-1 epidemic in Hebei province, China. Dolutegravir (DTG) will be conditionally used as a component of free antiretroviral therapy (ART) according to manual for …
View article: A decavalent composite mRNA vaccine against both influenza and COVID-19
A decavalent composite mRNA vaccine against both influenza and COVID-19 Open
The COVID-19 pandemic caused by SARS-CoV-2 has had a persistent and significant impact on global public health for 4 years. Recently, there has been a resurgence of seasonal influenza transmission worldwide. The co-circulation of SARS-CoV-…
View article: No genetic causal link between chronic spontaneous urticaria and Hashimoto thyroiditis in Asians: A bidirectional Mendelian randomization study
No genetic causal link between chronic spontaneous urticaria and Hashimoto thyroiditis in Asians: A bidirectional Mendelian randomization study Open
View article: An Exploration of the Antioxidative and Anti-Inflammatory Role of Lactiplantibacillus plantarum 106 via Improving Mitochondrial Function
An Exploration of the Antioxidative and Anti-Inflammatory Role of Lactiplantibacillus plantarum 106 via Improving Mitochondrial Function Open
In this present study, bioinformatics analysis and the experimental validation method were used to systematically explore the antioxidant activity and anti-inflammatory effect of Lactiplantibacillus plantarum A106, which was isolated from …
View article: Case Report: Scalp pityriasis versicolor may be a neglected problem
Case Report: Scalp pityriasis versicolor may be a neglected problem Open
Pityriasis versicolor, a common skin fungal infection, is typically observed on trunk and limb skin. Here, we highlight an unusual presentation: scalp involvement, often overlooked due to its asymptomatic, mildly scaly patches. We report f…
View article: Protective effects of a sunscreen lotion containing Calendula extracts on children′s skin after sun exposure: a single-center, randomized, parallel controlled clinical study
Protective effects of a sunscreen lotion containing Calendula extracts on children′s skin after sun exposure: a single-center, randomized, parallel controlled clinical study Open
摘要: 【摘要】 目的 研究含有金盏花提取物的温和倍护防晒乳对儿童皮肤日晒的防护效果、安全性及耐受性。方法 2022年7 - 8月以首都医科大学附属北京儿童医院为中心招募健康儿童,采用单中心、随机、平行对照临床研究方法,入组3 ~ 18岁健康儿童200例,按照1∶1的比例随机分为A组(左侧涂抹试验品、右侧涂抹对照品)或B组(右侧涂抹试验品、左侧涂抹对照品),涂抹后进行阳光暴露活动,在阳光暴露前后对颞部、上臂伸侧和前臂伸侧部位进行皮肤测试评估。试验品为含有金盏花提取物的温和倍…
View article: Efficacy and Safety of Crisaborole Ointment 2% in Chinese Patients Aged ≥ 2 Years with Mild to Moderate Atopic Dermatitis
Efficacy and Safety of Crisaborole Ointment 2% in Chinese Patients Aged ≥ 2 Years with Mild to Moderate Atopic Dermatitis Open
ClinicalTrials.gov, NCT04360187.
View article: An important issue of burnout among pre-hospital emergency medical personnel in Chengdu: a cross-sectional study
An important issue of burnout among pre-hospital emergency medical personnel in Chengdu: a cross-sectional study Open
Objective This survey aims to comprehensively understand occupational burnout among pre-hospital emergency medical personnel and explore associated risk factors. Methods A cross-sectional online survey using a census method was conducted b…
View article: Somatic <i>GNA11/GNAQ</i> variants in a cohort of Chinese children with phakomatosis pigmentovascularis
Somatic <i>GNA11/GNAQ</i> variants in a cohort of Chinese children with phakomatosis pigmentovascularis Open
Importance Postzygotic mutations in the GNAQ/GNA11 genes, which encode the G‐protein nucleotide binding protein alpha subunits, have been identified in patients with phakomatosis pigmentovascularis (PPV). However, little is known about the…
View article: Lymphatic Markers in Kaposiform Hemangioendothelioma: Implications for Tumor Invasiveness and β-blockers efficacy
Lymphatic Markers in Kaposiform Hemangioendothelioma: Implications for Tumor Invasiveness and β-blockers efficacy Open
Background: Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that usually expresses lymphatic markers. PROX1 can increase the local invasiveness of KHE in mice. Objectives: To evaluate whether the expression of lymphatic mark…
View article: Case Report: Itraconazole Oral Solution Continuous Therapy for Infantile Tinea Capitis
Case Report: Itraconazole Oral Solution Continuous Therapy for Infantile Tinea Capitis Open
Tinea capitis is a common fungal infection caused by dermatophytes in children, but it is rare in infants. Although oral itraconazole has been widely used to treat tinea capitis, its use in infants is limited due to its low prevalence in t…