Mei‐Chun Lin
YOU?
Author Swipe
View article: Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer
Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer Open
Early-onset breast cancer (EOBC) increases annually with unclear mechanisms and shows poor therapeutic responses and survival rates. We identify environmental exposure to the common plasticizer di-2-ethylhexyl phthalate (DEHP) as a contrib…
View article: Older adults’ Internet use behavior and its association with accelerometer-derived physical activity
Older adults’ Internet use behavior and its association with accelerometer-derived physical activity Open
Objective The aging population is thriving worldwide, and it is critical to improve the health of older adults through physical activity (PA). Although the Internet can promote PA in older adults, limited studies have used objective tools …
View article: <scp>C1GALT1</scp> expression predicts poor survival in osteosarcoma and is crucial for <scp>ABCC1</scp> transporter‐mediated doxorubicin resistance
<span>C1GALT1</span> expression predicts poor survival in osteosarcoma and is crucial for <span>ABCC1</span> transporter‐mediated doxorubicin resistance Open
Osteosarcoma is an aggressive bone malignancy with a high propensity for drug resistance and metastasis, leading to poor clinical outcomes. This study investigates the role of core 1 β1,3‐galactosyltransferase 1 (C1GALT1) in osteosarcoma, …
View article: The Prognostic Importance of Radiologic Extranodal Extension in Hypopharyngeal Carcinoma
The Prognostic Importance of Radiologic Extranodal Extension in Hypopharyngeal Carcinoma Open
Background Extranodal extension (ENE) had been included in the latest cancer staging system in hypopharyngeal squamous cell carcinoma (HypoSCC). However, the impact of ENE on HypoSCC survival and treatment outcomes are still unclear. Metho…
View article: The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC
The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC Open
Immunotherapy has revolutionized cancer treatment, but the lack of a reliable predictive biomarker for treatment response remains a challenge. Alpha-1,6-Mannosylglycoprotein 6-β-N-Acetylglucosaminyltransferase 5 (MGAT5) is a key regulator …
View article: Supplementary Figure 3 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 3 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
Effects of CD44 O-glycans on tumor sphere formation in breast cancer cells.
View article: Supplementary Figure 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
C1GALT1 knockdown in breast cancer cells did not cause significant changes in CD44 mRNA levels.
View article: Supplementary Figure 3 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 3 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
Effects of CD44 O-glycans on tumor sphere formation in breast cancer cells.
View article: Supplementary Figure 2 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 2 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
Construction of multiple mutations at O-glycosites in the stem region of CD44.
View article: Data from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Data from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
The glycoprotein CD44 is a key regulator of malignant behaviors in breast cancer cells. To date, hyaluronic acid (HA)-CD44 signaling pathway has been widely documented in the context of metastatic bone diseases. Core 1 β1,3-galactosyltrans…
View article: Supplementary Figure 2 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 2 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
Construction of multiple mutations at O-glycosites in the stem region of CD44.
View article: Supplementary Table 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Table 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
The abundance ratio of O-glycosylated proteins from mock and C1GALT1 knockdown breast cancer cells identified by mass spectrometry.
View article: Supplementary Table 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Table 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
The abundance ratio of O-glycosylated proteins from mock and C1GALT1 knockdown breast cancer cells identified by mass spectrometry.
View article: Supplementary Figure 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer
Supplementary Figure 1 from Truncation of GalNAc-type O-glycans suppresses CD44-mediated osteoclastogenesis and bone metastasis in breast cancer Open
C1GALT1 knockdown in breast cancer cells did not cause significant changes in CD44 mRNA levels.
View article: Enhanced ozone gas detection with Sb doped ZnO nanorods synthesized on MEMS microheater
Enhanced ozone gas detection with Sb doped ZnO nanorods synthesized on MEMS microheater Open
Metal oxide semiconductors infused with noble metals or metalloids are studied and employed in semiconductor sensors applications to a greater extent. In this study, antimony (Sb) is doped with ZnO in 4 different concentrations to compare …
View article: Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy
Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy Open
At present, PD-L1 scoring is the gold standard in evaluating a cancer patient's suitability for receiving PD-1/PD-L1 checkpoint inhibitor immunotherapy (CIT). Either tumor proportion score (TPS) or combined positive score (CPS) can be used…
View article: An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma
An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma Open
Changes in the oral microbiome are associated with oral squamous cell carcinoma (OSCC). Oral microbe-derived signatures have been utilized as markers of OSCC. However, the structure of the oral microbiome during OSCC recurrence and biomark…
View article: Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐<scp>PD</scp>‐1 immunotherapy in head and neck cancer
Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐<span>PD</span>‐1 immunotherapy in head and neck cancer Open
Cells in the tumor microenvironment (TME) communicate via membrane‐bound and secreted proteins, which are mostly glycosylated. Altered glycomes of malignant tumors influence behaviors of stromal cells. In this study, we showed that the los…
View article: In vitro assay identifying cisplatin resistance of head and neck squamous cell carcinoma
In vitro assay identifying cisplatin resistance of head and neck squamous cell carcinoma Open
• Demonstrate patient tumor slice organoid (PTSO) as an in vitro rapid platform in identifying cisplatin-resistant patients. • Water soluble tetrazolium salt (WST-8) assay was used a viability test for determining cisplatin-resistance. • C…
View article: Supplementary Figure 2 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Figure 2 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
Construction of multiple mutations at O-glycosites in the stem region of CD44.
View article: Supplementary Figure 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Figure 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
C1GALT1 knockdown in breast cancer cells did not cause significant changes in CD44 mRNA levels.
View article: Supplementary Figure 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Figure 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
C1GALT1 knockdown in breast cancer cells did not cause significant changes in CD44 mRNA levels.
View article: Supplementary Figure 3 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Figure 3 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
Effects of CD44 O-glycans on tumor sphere formation in breast cancer cells.
View article: Data from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Data from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
The glycoprotein CD44 is a key regulator of malignant behaviors in breast cancer cells. To date, hyaluronic acid (HA)-CD44 signaling pathway has been widely documented in the context of metastatic bone diseases. Core 1 β1,3-galactosyltrans…
View article: Supplementary Table 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Table 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
The abundance ratio of O-glycosylated proteins from mock and C1GALT1 knockdown breast cancer cells identified by mass spectrometry.
View article: Data from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Data from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
The glycoprotein CD44 is a key regulator of malignant behaviors in breast cancer cells. To date, hyaluronic acid (HA)-CD44 signaling pathway has been widely documented in the context of metastatic bone diseases. Core 1 β1,3-galactosyltrans…
View article: Supplementary Table 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Supplementary Table 1 from Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer Open
The abundance ratio of O-glycosylated proteins from mock and C1GALT1 knockdown breast cancer cells identified by mass spectrometry.