Lina Hamabe
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View article: Pericardial Sarcoma of Uncertain Origin in a Young Cat: A Case Report Highlighting Diagnostic Challenges and Thoracic Drainage in Palliative Management
Pericardial Sarcoma of Uncertain Origin in a Young Cat: A Case Report Highlighting Diagnostic Challenges and Thoracic Drainage in Palliative Management Open
Undifferentiated sarcoma is a malignant tumor characterized by the absence of a distinct cellular origin, as determined by morphological and immunohistochemical analyses, and is known for its highly invasive and proliferative behavior [...]
Evaluation of Changes in Heart Rate Variability Associated with Puppy Growth Using Phase-Rectified Signal Averaging (PRSA) and Non-Gaussianity Index Open
Heart rate variability (HRV) reflects autonomic nervous system (ANS) activity through nonlinear mechanisms, including complex beat-to-beat fluctuations and chaos-like dynamics of healthy cardiac rhythms. However, conventional HRV indices o…
Concomitant changes in regional myocardial deformation and intraventricular pressure gradients in normal and sedated goats: advanced multimodal echocardiographic study Open
This study utilizes two novel imaging techniques to assess changes observed in cardiac function in goats after sedation. Xylazine, an α2-agonist, induces loading alterations that disproportionately affect wall mechanics, reducing circumfer…
View article: The Role of Phase Angle in Non-Invasive Fluid Assessment in Dogs with Patent Ductus Arteriosus: A Novel Method in Veterinary Cardiology
The Role of Phase Angle in Non-Invasive Fluid Assessment in Dogs with Patent Ductus Arteriosus: A Novel Method in Veterinary Cardiology Open
Background: Patent ductus arteriosus (PDA) in dogs causes persistent left-to-right shunting, leading to pulmonary overcirculation, left heart volume overload, and potential congestive heart failure. Accurate assessment of fluid imbalance i…
View article: Phase Angle as a Non-Invasive Biomarker of Fluid Overload in Canine Right Heart Failure: A Bioelectrical Impedance Approach
Phase Angle as a Non-Invasive Biomarker of Fluid Overload in Canine Right Heart Failure: A Bioelectrical Impedance Approach Open
Background: Right heart failure (RHF) in dogs is marked by pathological fluid redistribution and extracellular fluid (ECF) accumulation, which intensifies cardiac work-load and disrupts systemic homeostasis. This study aimed to validate th…
Unroofed Coronary Sinus in a Dog: Diagnostic Utility of ECG-Gated Computed Tomography Open
A Labrador Retriever (4-year-old, castrated male) with signs of fatigue was diagnosed with an atrial septal defect at his primary veterinary clinic. Due to the uncertainty of this diagnosis, he was referred to the Tokyo University of Agric…
Thromboelastographic Assessment of Coagulation Profiles in Dogs with Cardiac Tumors and Their Relationship to Cardiac Function Open
Cardiac tumors are rare and linked to high mortality rates in both human and veterinary medicine. Despite their clinical significance, the effects of these tumors on coagulation and cardiac function remain poorly understood. This retrospec…
Remote Vital Sensing in Clinical Veterinary Medicine: A Comprehensive Review of Recent Advances, Accomplishments, Challenges, and Future Perspectives Open
Remote vital sensing in veterinary medicine is a relatively new area of practice, which involves the acquisition of data without invasion of the body cavities of live animals. This paper aims to review several technologies in remote vital …
View article: A Massive Adenoma of the Uterine Tube in a Young Intact Female Dog: Surgical Intervention and Outcome
A Massive Adenoma of the Uterine Tube in a Young Intact Female Dog: Surgical Intervention and Outcome Open
Tumors originating from the uterine tube are exceedingly rare in dogs, with limited clinical and therapeutic data available. This report illustrates a case of a uterine tube adenoma in a one-year-and-two-month-old intact female Pomeranian …
A Comprehensive Overview of Respiratory Compliance in Dogs Under General Anesthesia: Clinical Factors and Future Perspectives Open
Respiratory compliance reflects the ability of the lungs and chest wall to expand in response to increases in pressure. In this review, relevant studies were selected through a comprehensive literature search with the aim of summarizing an…
Effects of trans-mitral flow patterns and heart rate on intraventricular pressure gradients and E/E’ in the early stage of a rat model of hypertensive cardiomyopathy Open
Background The mitral inflow spectral is expressed as two separate waves: early diastolic trans-mitral flow velocity (E) and late diastolic trans-mitral flow velocity (A) waves. When the heart rate (HR) increases and the diastolic time dim…
View article: Advanced Imaging for Congenital Left Ventricular Diverticulum in a Dog: The Role of Electrocardiosynchronous CT
Advanced Imaging for Congenital Left Ventricular Diverticulum in a Dog: The Role of Electrocardiosynchronous CT Open
A 2-month-old Shiba Inu was presented to an emergency veterinary clinic with decreased activity and was diagnosed with pulmonary hypertension secondary to a ventricular septal defect. The dog was referred to the TUAT Veterinary Medical Cen…
Choledochoduodenostomy in a cat with extrahepatic biliary obstruction: simple side-to-side anastomosis technique Open
Case summary An 8-year-old castrated male mixed-breed cat was presented with recurrent vomiting, weight loss and abdominal distension. Blood work revealed hyperbilirubinaemia and elevated liver enzyme activities. Abdominal ultrasound and C…
Unilateral pyelonephritis with encapsulated structure in a dog Open
A young female Golden Retriever with a portosystemic shunt presented with hypoalbuminemia, hyperammonemia, and severe ascites, ultimately succumbing to the illness. Necropsy revealed renal papillary necrosis in the right renal pelvis. Hist…
Histological analysis of cheetah testes focused on the germ cells and Sertoli cells Open
Understanding of relationship between physiological condition and testicular function in captive cheetahs would be beneficial for their successful breeding and conservation. This study investigated the states of germ cells and Sertoli cell…
Assessment of myocardial function in Retrievers with dilated cardiomyopathy using 2D speckle tracking echocardiography: a pilot study Open
Early diagnosis of canine dilated cardiomyopathy (DCM) is complicated by the presence of a prolonged asymptomatic phase, for which a comprehensive evaluation of myocardial function is essential. This pilot study was conducted to evaluate t…
Remote Vital Sensing in Clinical Veterinary Medicine: A Comprehensive Review of Recent Advances, Accomplishments, Challenges and Future Perspectives Open
Remote vital sensing in veterinary medicine is a relatively new area of practice, which involves the acquisition of data without invasion of the body cavities of live animals. This paper aims to review several technologies in remote vital …
Evaluation of coagulation by thromboelastography and a velocity curve in dogs with parvoviral enteritis Open
Canine parvoviral enteritis (CPE) has a high mortality rate in untreated dogs due to systemic inflammation and multi-organ dysfunction. The inflammatory process can lead to coagulation abnormalities. This study aimed to evaluate the coagul…
Exploring sleep heart rate variability: linear, nonlinear, and circadian rhythm perspectives Open
Background Heart rate variability (HRV) is believed to possess the potential for disease detection. However, early identification of heart disease remains challenging, as HRV analysis in dogs primarily reflects the advanced stages of the d…
Evaluation of Alacepril Administration in Canine Patent Ductus Arteriosus According to Plasma Chymase Activity Open
Chymase in the renin–angiotensin system (RAS) actively contributes to cardiac disease progression. Chymase is activated to produce angiotensin II during tissue injury and is involved in hemodynamics. A recent study demonstrated that plasma…
Non-Invasive Assessment of the Intraventricular Pressure Using Novel Color M-Mode Echocardiography in Animal Studies: Current Status and Future Perspectives in Veterinary Medicine Open
The assessment of diastolic function has received great interest in order to comprehend its crucial role in the pathophysiology of heart failure and for the early identification of cardiac events. Silent changes in the intraventricular flo…
Secondary right atrial thrombosis in three dogs: Antithrombotics therapy and echocardiographic follow‐up Open
Three dogs were diagnosed with right atrial thrombosis, thought to be secondary to systemic diseases. Specifically, two cases had hyperadrenocorticism and one case was diagnosed with pancreatitis with acute renal injury. In all cases, the …
View article: Vascular ring anomaly with a right patent ductus arteriosus and a left aortic arch in a juvenile cat
Vascular ring anomaly with a right patent ductus arteriosus and a left aortic arch in a juvenile cat Open
This paper reports the clinical findings and surgical treatment of feline right patent ductus arteriosus (RPDA) with a left aortic arch. A two-month-old female Maine Coon was referred for an investigation of regurgitation after weaning. RP…
View article: Plasma Chymase Activity Reflects the Change in Hemodynamics Observed after the Surgical Treatment of Patent Ductus Arteriosus in Dogs
Plasma Chymase Activity Reflects the Change in Hemodynamics Observed after the Surgical Treatment of Patent Ductus Arteriosus in Dogs Open
Chymase is a protease stored in mast cell granules that produces angiotensin II (ANG II) from angiotensin I (ANG I) and is associated with tissue injury, inflammation, and remodeling, especially involving the cardiovascular system. As card…
Novel protocol to establish the myocardial infarction model in rats using a combination of medetomidine-midazolam-butorphanol (MMB) and atipamezole Open
Background Myocardial infarction (MI) is one of the most common cardiac problems causing deaths in humans. Previously validated anesthetic agents used in MI model establishment are currently controversial with severe restrictions because o…
Preliminary report of spinal cord injuries resulting from inappropriate microchip implantation in two puppies Open
Since the revised Animal Welfare and Management Law in Japan became effective on June 1st, 2022, it became mandatory for pet dogs and cats to have microchips implanted and registered prior to be sold. Two cases of spinal cord injury as the…
Novel color M-mode echocardiography for non-invasive assessment of the intraventricular pressure in goats: Feasibility, repeatability, and the effect of sedation Open
Background The intraventricular pressure difference (IVPD) and intraventricular pressure gradients (IVPG), estimated from color M-mode echocardiography (CMME) of the transmitral flow, have been introduced as novel indices for the evaluatio…
Evaluation of Left Ventricular Function in Healthy Retrievers Using Standard and 2D Speckle-Tracking Echocardiography Open
Standard echocardiography is vital for the assessment of cardiac performance in healthy and diseased animals. Similarly, two-dimensional speckle-tracking echocardiography (2D-STE) is an advanced echocardiographic technique that is becoming…
Intraventricular pressure gradient: A novel tool to assess the post-infarction chronic congestive heart failure Open
Congestive heart failure (CHF), the leading cause of death, is deemed a grave sequel of myocardial infarction (MI). The employment of left ventricular end-diastolic pressure (LVEDP), as a primary indication of CHF, becomes restricted owing…