Explanipedia

Implementation Outcomes Assessment of a Digital Clinical Support Tool for Intrapartum Care in Rural Kenya: Observational Analysis Open

Nhi Dinh, Smisha Agarwal, Lisa Avery, Priya Ponnappan, Judith Chelangat , et al. · 2022

Background iDeliver, a digital clinical support system for maternal and neonatal care, was developed to support quality of care improvements in Kenya. Objective Taking an implementation research approach, we evaluated the adoption and fide…

Validation of community health worker identification of maternal puerperal sepsis using a clinical diagnostic algorithm in Bangladesh and Pakistan Open

Amnesty LeFevre, Fatima Mir, Dipak Kumar Mitra, Shabina Ariff, Diwakar Mohan , et al. · 2021

In all sites, CHWs with limited training were able to identify signs and symptoms and to classify cases of PP sepsis with high validity. Integrating postpartum infection screening into existing community-based platforms and post-natal visi…

Implementation Outcomes Assessment of a Digital Clinical Support Tool for Intrapartum Care in Rural Kenya: Observational Analysis (Preprint) Open

Nhi Dinh, Smisha Agarwal, Lisa Avery, Priya Ponnappan, Judith Chelangat , et al. · 2021

BACKGROUND iDeliver, a digital clinical support system for maternal and neonatal care, was developed to support quality of care improvements in Kenya. OBJECTIVE Taking an implementation research approach, we evaluated the adoption and f…

Insights into the design, development and implementation of a novel digital health tool for skilled birth attendants to support quality maternity care in Kenya Open

Linda Bartlett, Lisa Avery, Priya Ponnappan, Judith Chelangat, Jackline Cheruiyot , et al. · 2021

Facility-based births with skilled attendants increased significantly in the past decade, yet global maternal mortality rates did not decline as rapidly as anticipated. Achieving the sustainable development goals for maternal and newborn h…

Impact of local terminology on the design of a community-based diagnostic and management algorithm for postpartum sepsis: findings of formative research Open

Shabina Ariff, Fatima Mir, Wafa Aftab, Farrukh Raza, Shujaat Zaidi , et al. · 2021

Background Postpartum sepsis is one of the leading causes of maternal mortality and morbidity in developing countries. This formative research elicits local terms used for postpartum illnesses and symptoms of postpartum sepsis with the aim…

Female Genital Tuberculosis in Pakistan – a Retrospective Review of 10-Year Laboratory Data and Analysis of 32 Cases Open

Tazeen Fatima, Rumina Hasan, Faisal Riaz Malik, Imran Ahmed, Linda Bartlett , et al. · 2021

Background: Female genital tuberculosis (FGTB) is an underobserved clinical entity owing to diagnostic challenges stemming from difficulty of obtaining diagnostic specimens and paucibacillary nature of the disease. Yet, FGTB is a cause of …

Health care seeking behaviors in Puerperal sepsis in rural Sindh, Pakistan: a qualitative study Open

Shabina Ariff, Ubaidullah Khan, Ali Turab, Sumra Kureishy, Farrukh Raza , et al. · 2020

Background Puerperal sepsis (PS) is one of the major causes of maternal death, contributing to 26 000 deaths per year in developing countries. Early recognition and treatment are essential to managing PS, but numerous social, cultural and …

Determinants of Health Care Seeking Behaviors in Puerperal Sepsis in Rural Sindh, Pakistan: A Qualitative Study Open

Shabina Ariff, Fatima Mir, Farhana Tabassum, Farrukh Raza, Atif Habib , et al. · 2020

Background: Puerperal sepsis (PS) is one of the major causes of maternal death, contributing to 26,000 deaths per year in developing countries. Early recognition and treatment are essential to managing PS, but numerous social, cultural and…

Postpartum endometritis and infection following incomplete or complete abortion: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data Open

Caroline E. Rouse, Linda O. Eckert, Flor M. Muñoz, Jeffrey S. A. Stringer, Sonali Kochhar , et al. · 2019

Measuring the quality of maternal and care processes at the time of delivery in sub-Saharan Africa: development and validation of a short index Open

Vandana Tripathi, Catherine Stanton, Donna M. Strobino, Linda Bartlett · 2019

Risk of Early-Onset Neonatal Group B Streptococcal Disease With Maternal Colonization Worldwide: Systematic Review and Meta-analyses Open

Neal Russell, Anna C. Seale, Catherine O’Sullivan, Kirsty Le Doaré, Paul T. Heath , et al. · 2017

The risk of EOGBS among GBS-colonized pregnant women, from this first systematic review, is consistent with previous estimates from single studies (1%-2%). Increasing IAP coverage was linearly associated with decreased risk of EOGBS diseas…

Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses Open

Neal Russell, Anna C. Seale, Megan O’Driscoll, Catherine O’Sullivan, Fiorella Bianchi-Jassir , et al. · 2017

Incidence data on maternal GBS disease in developing regions are lacking. In developed regions the incidence is low, as are the sequelae for the mother, but the risk to the fetus and newborn is substantial. The timing of GBS disease sugges…

Intrapartum Antibiotic Chemoprophylaxis Policies for the Prevention of Group B Streptococcal Disease Worldwide: Systematic Review Open

Kirsty Le Doaré, Megan O’Driscoll, Kim Turner, Farah Seedat, Neal Russell , et al. · 2017

There is considerable heterogeneity in IAP screening policies and coverage worldwide. Alternative global strategies, such as maternal vaccination, are needed to enhance the scope of global prevention of GBS disease.

Neonatal Encephalopathy With Group B Streptococcal Disease Worldwide: Systematic Review, Investigator Group Datasets, and Meta-analysis Open

Cally J Tann, Kathryn A. Martinello, Samantha Sadoo, Joy E Lawn, Anna C. Seale , et al. · 2017

The consistent increased proportion of GBS disease in NE and significant increased risk of mortality provides evidence that GBS infection contributes to NE. Increased information regarding this and other organisms is important to inform in…

Group B Streptococcal Disease Worldwide for Pregnant Women, Stillbirths, and Children: Why, What, and How to Undertake Estimates? Open

Joy E Lawn, Fiorella Bianchi-Jassir, Neal Russell, Maya Kohli-Lynch, Cally J Tann , et al. · 2017

Improving maternal, newborn, and child health is central to Sustainable Development Goal targets for 2030, requiring acceleration especially to prevent 5.6 million deaths around the time of birth. Infections contribute to this burden, but …

Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses Open

Maya Kohli-Lynch, Neal Russell, Anna C. Seale, Ziyaad Dangor, Cally J Tann , et al. · 2017

BACKGROUND: Survivors of infant group B streptococcal (GBS) disease are at risk of neurodevelopmental impairment (NDI), a burden not previously systematically quantified. This is the 10th of 11 articles estimating the burden of GBS disease…

Estimates of the Burden of Group B Streptococcal Disease Worldwide for Pregnant Women, Stillbirths, and Children Open

Anna C. Seale, Fiorella Bianchi-Jassir, Neal Russell, Maya Kohli-Lynch, Cally J Tann , et al. · 2017

Our conservative estimates suggest that GBS is a leading contributor to adverse maternal and newborn outcomes, with at least 409000 (UR, 144000-573000) maternal/fetal/infant cases and 147000 (UR, 47000-273000) stillbirths and infant deaths…

Stillbirth With Group B Streptococcus Disease Worldwide: Systematic Review and Meta-analyses Open

Anna C. Seale, Hannah Blencowe, Fiorella Bianchi-Jassir, Nicholas D. Embleton, Quique Bassat , et al. · 2017

GBS is likely an important cause of stillbirth, especially in Africa. However, data are limited in terms of geographic spread, with no data from Asia, and cases worldwide are probably underestimated due to incomplete case ascertainment. Mo…

Maternal Disease With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses Open

Jennifer Hall, Nadine Hack Adams, Linda Bartlett, Anna C. Seale, Theresa Lamagni , et al. · 2017

BACKGROUND: Infections such as group B Streptococcus (GBS) are an important cause of maternal sepsis, yet limited data on epidemiology exist. This article, the third of 11, estimates the incidence of maternal GBS disease worldwide. METHODS…

Infant Group B Streptococcal Disease Incidence and Serotypes Worldwide: Systematic Review and Meta-analyses Open

Lola Madrid, Anna C. Seale, Maya Kohli-Lynch, Karen Edmond, Joy E Lawn , et al. · 2017

The incidence of infant GBS disease remains high in some regions, particularly Africa. We likely underestimated incidence in some contexts, due to limitations in case ascertainment and specimen collection and processing. Burden in Asia req…

Preterm Birth Associated With Group B Streptococcus Maternal Colonization Worldwide: Systematic Review and Meta-analyses Open

Fiorella Bianchi-Jassir, Anna C. Seale, Maya Kohli-Lynch, Joy E Lawn, Carol J. Baker , et al. · 2017

From this review, there is evidence to suggest that preterm birth is associated with maternal GBS colonization, especially where there is evidence of ascending infection (bacteriuria). Several biases reduce the chance of detecting an effec…

Progress and inequities in maternal mortality in Afghanistan (RAMOS-II): a retrospective observational study Open

Linda Bartlett, Amnesty LeFevre, Linnea Zimmerman, Sayed Ataullah Saeedzai, Sabera Turkmani , et al. · 2017

The development and evaluation of a community-based clinical diagnosis tool and treatment regimen for postpartum sepsis in Bangladesh and Pakistan Open

Linda Bartlett, Amnesty LeFevre, Fatima Mir, Sajid Soofi, Syeda Muntaha Arif , et al. · 2016

Diagnostic methods to determine microbiology of postpartum endometritis in South Asia: laboratory methods protocol used in the Postpartum Sepsis Study: a prospective cohort study Open

Sadia Shakoor, Megan E. Reller, Amnesty LeFevre, Aneeta Hotwani, Shahida Qureshi , et al. · 2016

The results emanating from this study will provide microbiologic evidence of the etiology and susceptibility pattern of agents recovered from patients with postpartum fever in South Asia, data critical for the development of evidence-based…

Direct observation of respectful maternity care in five countries: a cross-sectional study of health facilities in East and Southern Africa Open

Heather Rosen, P Lynam, Catherine Carr, Veronica Reis, Jim Ricca , et al. · 2015

Facility-based active management of the third stage of labour: assessment of quality in six countries in sub-Saharan Africa Open

Linda Bartlett, David Cantor, P Lynam, Gurpreet Kaur, Barbara Rawlins , et al. · 2015

In the study countries, quality and coverage of the active management of the third stage of labour were high. However, to improve active management, there needs to be more research on optimizing the timing of uterotonic administration. Tra…

Development and Validation of an Index to Measure the Quality of Facility-Based Labor and Delivery Care Processes in Sub-Saharan Africa Open

Vandana Tripathi, Catherine Stanton, Donna M. Strobino, Linda Bartlett · 2015

As facility deliveries increase and the global community pays greater attention to the role of care quality in achieving further maternal and newborn mortality reduction, the QoPIIPC index may be a valuable measure. This index complements …

Use of clinical guidelines: perspectives from clinicians in paediatric and maternity hospitals in Kabul, Afghanistan Open

Hamish Graham, Mariam Tokhi, Anbrasi Edward, Ahmad Shah Salehi, Sabera Turkmani , et al. · 2015

This study explored the perceived value, role and reported use of clinical guidelines by clinicians in urban paediatric and maternity hospital settings, and the effect of current implementation strategies on clinician attitudes, knowledge …

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