Linda E. Scheffers
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View article: The effect of first intervention on cardiac parameters in patients with acromegaly: a systematic review
The effect of first intervention on cardiac parameters in patients with acromegaly: a systematic review Open
Objective Cardiovascular disease in acromegaly patients remains a major cause of morbidity and all-cause mortality. This systematic review investigates the effect of the first growth hormone-lowering intervention on cardiac parameters. Des…
View article: Health-Related Quality of Life and Fatigue in Children with Pompe Disease
Health-Related Quality of Life and Fatigue in Children with Pompe Disease Open
View article: A 12-week lifestyle intervention: effects on fatigue, fear, and nutritional status in children with a Fontan circulation
A 12-week lifestyle intervention: effects on fatigue, fear, and nutritional status in children with a Fontan circulation Open
Introduction Children and adolescents with a Fontan circulation are less physically active compared to healthy peers. In the current study, effects of a 12-week lifestyle intervention on fatigue, fears regarding exercise, caloric intake, r…
View article: Leg-focused high-weight resistance training improves ventricular stroke volume, exercise capacity and strength in young patients with a Fontan circulation
Leg-focused high-weight resistance training improves ventricular stroke volume, exercise capacity and strength in young patients with a Fontan circulation Open
Aims Effective therapy to improve exercise capacity in Fontan patients is lacking. Leg-focused high-weight resistance training might augment the peripheral muscle pump and thereby improve exercise capacity. Methods and results This randomi…
View article: Body composition in patients with Fontan physiology: a systematic review
Body composition in patients with Fontan physiology: a systematic review Open
Fontan circulation is a highly abnormal circulatory state that may affect various organ systems. The effect on body composition is an important factor to assess the condition of the patient. This systematic review assesses body composition…
View article: Stress imaging in patients with a Fontan circulation: A systematic review
Stress imaging in patients with a Fontan circulation: A systematic review Open
View article: Challenges in body composition assessment using air-displacement plethysmography by BOD POD in pediatric and young adult patients
Challenges in body composition assessment using air-displacement plethysmography by BOD POD in pediatric and young adult patients Open
We conclude that ADP by BOD POD in children and young adults is non-invasive and user-friendly. However, in specific pediatric populations, BOD POD has several limitations and high (technical) failure-rates, especially in young children wi…
View article: Physical Training and Healthy Diet Improved Bowel Symptoms, Quality of Life, and Fatigue in Children With Inflammatory Bowel Disease
Physical Training and Healthy Diet Improved Bowel Symptoms, Quality of Life, and Fatigue in Children With Inflammatory Bowel Disease Open
Objectives: Physical activity programs have been suggested as adjunctive therapy in adult inflammatory bowel disease (IBD) patients. We assessed the effects of a 12‐week lifestyle intervention in children with IBD. Methods: This study was …
View article: Physical training and high‐protein diet improved muscle strength, parent‐reported fatigue, and physical quality of life in children with Pompe disease
Physical training and high‐protein diet improved muscle strength, parent‐reported fatigue, and physical quality of life in children with Pompe disease Open
Exercise has proven to be an effective adjuvant treatment to enzyme replacement therapy (ERT) in mildly affected adult Pompe patients. The aim of this study was to investigate the effects of a 12‐week tailored lifestyle intervention, consi…
View article: Effects of enzyme replacement therapy on cardiac function in classic infantile Pompe disease
Effects of enzyme replacement therapy on cardiac function in classic infantile Pompe disease Open
View article: Study Protocol of the Exercise Study: Unraveling Limitations for Physical Activity in Children With Chronic Diseases in Order to Target Them With Tailored Interventions—A Randomized Cross Over Trial
Study Protocol of the Exercise Study: Unraveling Limitations for Physical Activity in Children With Chronic Diseases in Order to Target Them With Tailored Interventions—A Randomized Cross Over Trial Open
Introduction: Physical activity is associated with many physiological and psychological health benefits across the lifespan. Children with a chronic disease often have lower levels of daily physical activity, and a decreased exercise capac…
View article: P515 A 12-week tailored physical training program including dietary advice in children with Inflammatory Bowel Disease: a randomized crossover trial
P515 A 12-week tailored physical training program including dietary advice in children with Inflammatory Bowel Disease: a randomized crossover trial Open
Background Inflammatory Bowel Disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. Recently, physical activity has been suggested to improve the quality of life and course of disease in adult IBD patients. The aim…
View article: Physical exercise training in patients with a Fontan circulation: A systematic review
Physical exercise training in patients with a Fontan circulation: A systematic review Open
Background Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training. This …