Lindsay Brown
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View article: Plant-Based Functional Foods from Borneo
Plant-Based Functional Foods from Borneo Open
Borneo, the third-largest island in the world, is shared between Malaysia (Sabah and Sarawak), Indonesia (Kalimantan) and Brunei. As a biodiversity hotspot, it is home to about 15,000 flowering plants and 3000 tree species, of which many a…
View article: Improving Undernutrition with Microalgae
Improving Undernutrition with Microalgae Open
Undernutrition is an important global health problem, especially in children and older adults. Both reversal of maternal and child undernutrition and heathy ageing have become United Nations-supported global initiatives, leading to increas…
View article: Bioactive compounds of spent coffee grounds and their potential use as functional food
Bioactive compounds of spent coffee grounds and their potential use as functional food Open
Hot brewed coffee is the most popular hot beverage in the world, and its health properties have been published in the literature (1) . Conversely, over the past decade, cold-brewed coffee has gained popularity, but its eventual nutritional…
View article: The Effectiveness of Orthoses as a Conservative Treatment in Treating Carpometacarpal Joint Osteoarthritis: A Systematic Review
The Effectiveness of Orthoses as a Conservative Treatment in Treating Carpometacarpal Joint Osteoarthritis: A Systematic Review Open
Objectives: The purpose of this research is to review the evidence regarding the impact and effectiveness of orthoses on pain, pinch, and grip strength for individuals diagnosed with carpometacarpal joint osteoarthritis. Methods: A systema…
View article: Review: Ageing, Health and Macroalgae
Review: Ageing, Health and Macroalgae Open
Maintaining health during ageing has become a major public health initiative as the proportion of the world’s population aged over 65 years has increased markedly. Macroalgae have been incorporated in the diet for generations, especially i…
View article: Review of: "How to enjoy your healthy life after 70—suggestions from the science of longevity"
Review of: "How to enjoy your healthy life after 70—suggestions from the science of longevity" Open
Potential competing interests: No potential competing interests to declare.This topic is very important but this manuscript does not provide clear suggestions as suggested by the title.Rather, it provides broad statements without data or r…
View article: A National Survey of Hereditary Angioedema and Acquired C1 Inhibitor Deficiency in the United Kingdom
A National Survey of Hereditary Angioedema and Acquired C1 Inhibitor Deficiency in the United Kingdom Open
View article: The Potential of Spent Coffee Grounds in Functional Food Development
The Potential of Spent Coffee Grounds in Functional Food Development Open
Coffee is a popular and widely consumed beverage worldwide, with epidemiological studies showing reduced risk of cardiovascular disease, cancers and non-alcoholic fatty liver disease. However, few studies have investigated the health effec…
View article: Testing the impact of a skill-targeted social and emotional learning curriculum and its variation by pre- and postmigration conflict experiences: A cluster randomized trial with Syrian refugee children in Lebanon.
Testing the impact of a skill-targeted social and emotional learning curriculum and its variation by pre- and postmigration conflict experiences: A cluster randomized trial with Syrian refugee children in Lebanon. Open
View article: Potential Benefits of Anthocyanins in Chronic Disorders of the Central Nervous System
Potential Benefits of Anthocyanins in Chronic Disorders of the Central Nervous System Open
Anthocyanins have been shown to be effective in chronic diseases because of their antioxidant and anti-inflammatory effects together with changes in the gut microbiota and modulation of neuropeptides such as insulin-like growth factor-1. T…
View article: Freshwater Macroalgae, Oedogonium, Grown in Wastewater Reduce Diet-Induced Metabolic Syndrome in Rats
Freshwater Macroalgae, Oedogonium, Grown in Wastewater Reduce Diet-Induced Metabolic Syndrome in Rats Open
Macroalgae produce compounds with industrial, pharmaceutical and nutritional applications. In this study, biomass from the freshwater macroalgal genus Oedogonium was grown in either treated municipal wastewater (M) or ash dam water from a …
View article: Anthocyanins in Chronic Diseases: The Power of Purple
Anthocyanins in Chronic Diseases: The Power of Purple Open
Anthocyanins are mainly purple-coloured phenolic compounds of plant origin that as secondary metabolites are important in plant survival. Understanding their health benefits in humans requires sourcing these unstable compounds in sufficien…
View article: Tropical fruits from Australia as potential treatments for metabolic syndrome
Tropical fruits from Australia as potential treatments for metabolic syndrome Open
View article: Two Opposing Functions of Angiotensin-Converting Enzyme (ACE) That Links Hypertension, Dementia, and Aging
Two Opposing Functions of Angiotensin-Converting Enzyme (ACE) That Links Hypertension, Dementia, and Aging Open
A 2018 report from the American Heart Association shows that over 103 million American adults have hypertension. The angiotensin-converting enzyme (ACE) (EC 3.4.15.1) is a dipeptidyl carboxylase that, when inhibited, can reduce blood press…
View article: BSACI 2021 guideline for the management of egg allergy
BSACI 2021 guideline for the management of egg allergy Open
We are writing in response to the British Society of Allergy and Clinical Immunology (BSACI) egg allergy guideline, published earlier this year in your Journal [1]. The guideline includes a section on the home introduction of egg. This mak…
View article: Addressing the Insufficient Availability of EPA and DHA to Meet Current and Future Nutritional Demands
Addressing the Insufficient Availability of EPA and DHA to Meet Current and Future Nutritional Demands Open
Tocher and colleagues [...]
View article: Brown Seaweed Sargassum siliquosum as an Intervention for Diet-Induced Obesity in Male Wistar Rats
Brown Seaweed Sargassum siliquosum as an Intervention for Diet-Induced Obesity in Male Wistar Rats Open
The therapeutic potential of Sargassum siliquosum grown in Australian tropical waters was tested in a rat model of metabolic syndrome. Forty-eight male Wistar rats were divided into four groups of 12 rats and each group was fed a different…
View article: Rind from Purple Mangosteen (Garcinia mangostana) Attenuates Diet-Induced Physiological and Metabolic Changes in Obese Rats
Rind from Purple Mangosteen (Garcinia mangostana) Attenuates Diet-Induced Physiological and Metabolic Changes in Obese Rats Open
The pulp of the purple mangosteen, Garcinia mangostana, is a popular tropical fruit but the rind containing xanthones such as α-mangostin together with procyanidins and anthocyanidins is usually discarded as waste. However, this rind has b…
View article: Effectiveness of the medical response teams to the 2014 Ebola outbreak: African immigrants perceptions
Effectiveness of the medical response teams to the 2014 Ebola outbreak: African immigrants perceptions Open
During the 2014 Ebola virus outbreak, international medical response teams were sent to help contain the virus. The purpose of this study was to explore the effectiveness of the medical response teams from African immigrants’ perspectives.…
View article: Caulerpa lentillifera (Sea Grapes) Improves Cardiovascular and Metabolic Health of Rats with Diet-Induced Metabolic Syndrome
Caulerpa lentillifera (Sea Grapes) Improves Cardiovascular and Metabolic Health of Rats with Diet-Induced Metabolic Syndrome Open
Caulerpa lentillifera (sea grapes) is widely consumed in South-East Asia as a low-energy food with high contents of vitamins and minerals. This study investigated dried sea grapes containing 16.6% insoluble fibre commercially produced in V…
View article: Tropical Seaweeds Improve Cardiovascular and Metabolic Health of Diet-Induced Obese and Hypertensive Rats
Tropical Seaweeds Improve Cardiovascular and Metabolic Health of Diet-Induced Obese and Hypertensive Rats Open
Seaweeds have been an important part of the diet of coastal populations in Asia possibly for millennia but only a few scattered coastal communities in Europe and the Americas have maintained these traditions. Our studies have investigated …
View article: DNA Methylation in Adipose Tissue and Metabolic Syndrome
DNA Methylation in Adipose Tissue and Metabolic Syndrome Open
Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence with the processes including DNA methylation, histone modifications and RNA-associated silencing [...]
View article: Tropical foods as functional foods for metabolicsyndrome
Tropical foods as functional foods for metabolicsyndrome Open
Tropical foods are an integral part of the traditional diet and form part of traditional medicine in many countries. This review examines the potential of tropical foods to treat signs of metabolic syndrome, defined as a chronic low-grade …
View article: Design and synthesis of novel proline based factor XIa selective inhibitors as leads for potential new anticoagulants
Design and synthesis of novel proline based factor XIa selective inhibitors as leads for potential new anticoagulants Open
View article: Oral nutritional supplements for preventing surgical site infections: protocol for a systematic review and meta-analysis
Oral nutritional supplements for preventing surgical site infections: protocol for a systematic review and meta-analysis Open
View article: Pelargonidin 3-glucoside-enriched strawberry attenuates symptoms of DSS-induced inflammatory bowel disease and diet-induced metabolic syndrome in rats
Pelargonidin 3-glucoside-enriched strawberry attenuates symptoms of DSS-induced inflammatory bowel disease and diet-induced metabolic syndrome in rats Open
View article: Cholesterol versus Inflammation as Cause of Chronic Diseases
Cholesterol versus Inflammation as Cause of Chronic Diseases Open
Tsoupras and colleagues have postulated, in a recent review in Nutrients, that the key to reducing the incidence of cardiovascular disease is to control the activities of inflammatory mediators such as platelet-activating factor (PAF) by d…
View article: Linseed Components Are More Effective Than Whole Linseed in Reversing Diet-Induced Metabolic Syndrome in Rats
Linseed Components Are More Effective Than Whole Linseed in Reversing Diet-Induced Metabolic Syndrome in Rats Open
Linseed is a dietary source of plant-based ω–3 fatty acids along with fiber as well as lignans including secoisolariciresinol diglucoside (SDG). We investigated the reversal of signs of metabolic syndrome following addition of whole linsee…
View article: Low-Dose Curcumin Nanoparticles Normalise Blood Pressure in Male Wistar Rats with Diet-Induced Metabolic Syndrome
Low-Dose Curcumin Nanoparticles Normalise Blood Pressure in Male Wistar Rats with Diet-Induced Metabolic Syndrome Open
Nanoparticle formulations improve bioavailability and so may allow low-dose formulations of food-derived compounds such as curcumin to attenuate chronic systemic disease despite intrinsically low oral bioavailability. The current study ind…
View article: Green coffee ameliorates components of diet-induced metabolic syndrome in rats
Green coffee ameliorates components of diet-induced metabolic syndrome in rats Open