Lindsey A. Morgan
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View article: Use of Continuous EEG Monitoring and Short-term Outcomes in Critically Ill Children
Use of Continuous EEG Monitoring and Short-term Outcomes in Critically Ill Children Open
View article: Telehealth usage patterns among pediatric neurology patients during and after the COVID-19 pandemic in Washington state
Telehealth usage patterns among pediatric neurology patients during and after the COVID-19 pandemic in Washington state Open
Background The COVID-19 pandemic accelerated the adoption of telehealth across the United States. While telehealth usage during the pandemic has been described, evaluating utilization across different policy periods is necessary to underst…
View article: Time to treatment in pediatric patients with repeated episodes of status epilepticus
Time to treatment in pediatric patients with repeated episodes of status epilepticus Open
View article: Treating seizures faster: The Quality Improvement in Time to Treat Status Epilepticus (QuITT-SE) multicenter randomized stepped wedge clinical trial protocol
Treating seizures faster: The Quality Improvement in Time to Treat Status Epilepticus (QuITT-SE) multicenter randomized stepped wedge clinical trial protocol Open
View article: Time Is Brain
Time Is Brain Open
View article: Time to Treatment in Pediatric Patients with Repeated Episodes of Status Epilepticus
Time to Treatment in Pediatric Patients with Repeated Episodes of Status Epilepticus Open
Objective To compare pediatric patients who presented with repeated status epilepticus episodes to patients with a single episode of status epilepticus and identify distinguishing clinical factors. Methods Retrospective analysis of a multi…
View article: Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children
Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children Open
This study provides Class II evidence that patient and clinical factors may predict RSE in children with convulsive seizures.
View article: A Multidisciplinary Pediatric Neurology Clinic for Systematic Follow-up of Children with Neurologic Sequelae of COVID-19
A Multidisciplinary Pediatric Neurology Clinic for Systematic Follow-up of Children with Neurologic Sequelae of COVID-19 Open
Clinical guidance on outpatient follow-up of children hospitalized with acute neurologic complications of SARS-CoV2 infection is needed. We describe the clinical infrastructure of our pediatric neurology post-Covid clinic, including our cl…
View article: Imaging Findings in Children Presenting with CNS Nelarabine Toxicity
Imaging Findings in Children Presenting with CNS Nelarabine Toxicity Open
Nelarabine is a nucleoside analog critical for the treatment of patients with T-cell acute lymphoblastic leukemia/lymphoma. However, clinical peripheral and central neurologic adverse events associated with nelarabine administration have b…
View article: Epilepsy and proxy‐reported health‐related quality of life in children and young people with non‐ambulatory cerebral palsy
Epilepsy and proxy‐reported health‐related quality of life in children and young people with non‐ambulatory cerebral palsy Open
Aim To assess the association between epilepsy characteristics and proxy‐reported health‐related quality of life (HRQoL) in children and young people with non‐ambulatory cerebral palsy (CP) and seizures. Method This was a cross‐sectional s…
View article: Retrospective Evaluation of First-line Levetiracetam use for Neonatal Seizures after Congenital Heart Defect repair with or without Extracorporeal Membrane Oxygenation
Retrospective Evaluation of First-line Levetiracetam use for Neonatal Seizures after Congenital Heart Defect repair with or without Extracorporeal Membrane Oxygenation Open
OBJECTIVE Levetiracetam (LEV) efficacy for neonatal seizures is debated. We evaluated LEV as a first line anti-seizure medicine (ASM) in neonates following neonatal congenital heart defect (CHD) repair who did not require extracorporeal me…
View article: Benzodiazepine administration patterns before escalation to second‐line medications in pediatric refractory convulsive status epilepticus
Benzodiazepine administration patterns before escalation to second‐line medications in pediatric refractory convulsive status epilepticus Open
Objective This study was undertaken to evaluate benzodiazepine (BZD) administration patterns before transitioning to non‐BZD antiseizure medication (ASM) in pediatric patients with refractory convulsive status epilepticus (rSE). Methods Th…
View article: Factors associated with long‐term outcomes in pediatric refractory status epilepticus
Factors associated with long‐term outcomes in pediatric refractory status epilepticus Open
Objective This study was undertaken to describe long‐term clinical and developmental outcomes in pediatric refractory status epilepticus (RSE) and identify factors associated with new neurological deficits after RSE. Methods We performed r…
View article: Design and implementation of electronic health record common data elements for pediatric epilepsy: Foundations for a learning health care system
Design and implementation of electronic health record common data elements for pediatric epilepsy: Foundations for a learning health care system Open
Objective Common data elements (CDEs) are standardized questions and answer choices that allow aggregation, analysis, and comparison of observations from multiple sources. Clinical CDEs are foundational for learning health care systems, a …
View article: First-line medication dosing in pediatric refractory status epilepticus
First-line medication dosing in pediatric refractory status epilepticus Open
This study provides Class III evidence that patients with RSE who present with male sex, older age, no prior diagnosis of epilepsy, and delayed BZD treatment are more likely to receive low total BZD doses. This study provides Class III evi…
View article: Association of guideline publication and delays to treatment in pediatric status epilepticus
Association of guideline publication and delays to treatment in pediatric status epilepticus Open
Publication of evidence on delays in time to treatment was not associated with improvements in time to treatment of rSE, although it was associated with an increase in the proportion of patients who received at least 1 BZD before hospital …
View article: Factors associated with treatment delays in pediatric refractory convulsive status epilepticus
Factors associated with treatment delays in pediatric refractory convulsive status epilepticus Open
Intermittent rSE and out-of-hospital rSE onset are independently associated with longer delays to administration of the first BZD and the first non-BZD AED in pediatric rSE. These factors identify potential targets for intervention to redu…
View article: Neuropsychological Effects of Anticonvulsants
Neuropsychological Effects of Anticonvulsants Open
Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnos…
View article: Spectrum of SCN8A-Related Epilepsy
Spectrum of SCN8A-Related Epilepsy Open
Investigators from the EuroEPINOMICS European research consortium studied 17 patients with epileptic encephalopathy due to SCN8A mutations and reported the specific genetic and phenotypic features.